zidovudine

zidovudine information and resources from the National Cancer Institute

zidovudine

A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. zidovudine

A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.

news articles



FDA Approves Generic Capsule Form of HIV/AIDS Drug 01 Apr 2006
HealthCentral.com The same drug, zidovudine, already had approval in tablet and oral dosage forms. The approval of the capsule form of the drug, made ...

Lifetime closing high for Sensex, Nifty 01 Apr 2006
Equity Bulls, ...of $ 20-50 million each. It also got final approval from the USFDA for its Zidovudine capsules USP 100 mg. Bata India surged 11% to ...

MNP+, INP+ oppose patent for ARV drug 01 Apr 2006
KanglaOnline, ...office by GlaxoSmithKline (GSK) for Combivir, an anti-retroviral drug that is a fixed-dose combination of two essential AIDS drugs zidovudine/lamivudine (AZT ...

Aurobindo Pharma receives USFDA nod for Zidovudine capsules Mar 29, 2006
NewKerala.com, Mumbai: Hyderabad-based Aurobindo Pharma Limited has received USFDA approval to market Zidovudine capsules, intended to use for the treatment of HIV-1 infection ...

FDA Announces Tentative Approval for Generic Zidovudine, 100 mg ... Mar 29, 2006
PharmaLive.com (press release), ROCKVILLE, Md., March 29, 2006--The Food and Drug Administration, on March 27, 2006, granted tentative approval for zidovudine 100 mg capsules manufactured by ...

Aurobindo Pharma gets USFDA nod for Zidovudine caps Mar 29, 2006
India Infoline.com, Aurobindo Pharma Ltd on Wednesday announced that the Company has received final approval for Zidovudine capsules USP 100 mg from US FDA. ...

Aurobindo gets FDA nod for anti-AIDS drug Mar 29, 2006
Sify, Mumbai: Aurobindo Pharma Ltd., said on Wednesday it had received US Food and Drug Administration approval for Zidovudine capsules, which prevents reproduction ...

Techs lift Indian shares Mar 30, 2006
Gulf Daily News, Pharma firmed 1.6pc to 674.75 rupees after it said on Wednesday it had received US Food and Drug Administration approval for Zidovudine capsules, which ...

Initial Antiretroviral Treatment of HIV Infection Mar 10, 2006
eMaxHealth.com, ...levels of the virus, with fewer problems of anemia, fatigue and nausea than another widely used combination of antiretrovirals, zidovudine and lamivudine (AZT ...

NGO opposes GSK’s bid for AIDS drug Mar 30, 2006
Economic Times, ...patent application of multinational pharma major GlaxoSmithKline for Combivir, a fixed dose combination of two essential AIDS drugs--Zidovudine and Lamivudine. ...

Market Mood: This Morning Mar 29, 2006
Sify, Aurobindo Pharma may firm up following an announcement from the company that it has received final approval for Zidovudine capsules USP 100 mg from US FDA. ...

New Antiretroviral Strategies for First-Line and "Switch" Patients ... Mar 22, 2006
Medscape (subscription) 8] is a double-blinded, placebo-controlled trial that compares the safety and efficacy of abacavir or nevirapine with fixed dose zidovudine/lamivudine in ...

Aurobindo receives first NDA approval for HIV-1 drug from US FDA Mar 16, 2006
domain-B, Aurobindo Pharma Ltd has announced having received the first new drug approval (NDA) from US FDA for Lamivudine 150mg / Zidovudine 300mg for fixed-dose ...

Aurobindo gets 1st NDA approval for ARV product Mar 16, 2006
India Infoline.com, Aurobindo Pharma Ltd on Thursday announced that the Company has received the first New Drug Approval (NDA) from US FDA for Lamivudine 150 mg/Zidovudine 300 mg ...

CROI: early vs delayed Trizivir in TB/HIV coinfected - no ... Mar 2, 2006
Aidsmap, Starting antiretroviral treatment with Trizivir (abacavir, zidovudine and lamivudine fixed dose combination) almost immediately after beginning TB treatment ...

Aurobindo gets NDA approval from USFDA Mar 15, 2006
Hindustan Times, Aurobindo Pharma Ltd said on Thursday that it has received the first New Drug Approval (NDA) from USFDA for Lamivudine 150 mg, Zidovudine 300 mg fixed-dose ...

ADVENTRX Announces Upcoming Scientific Conference Presentations Mar 28, 2006
Yahoo! News (press release) ADVENTRX will present "Synergistic antiviral activity and additive cytotoxicity of Thiovir combined with zidovudine" at the HIV Pathogenesis Meeting, in ...

Aurobindo gets NDA approval from USFDA Mar 15, 2006
Hindu, Mumbai, March 16. (PTI) Aurobindo Pharma Ltd today said it has received the first New Drug Approval (NDA) from USFDA for Lamivudine 150 mg, Zidovudine 300 mg ...

ADVENTRX Announces Upcoming Scientific Conference Presentations Mar 28, 2006
PR Newswire (press release), ...at upcoming scientific conferences: ADVENTRX will present "Synergistic antiviral activity and additive cytotoxicity of Thiovir combined with zidovudine" at the ...

Co-packaged AZT/3TC/efavirenz regimen approved for use in PEPFAR ... Mar 9, 2006
Aidsmap, US Food and Drug Administration this week granted tentative approval for a copackaged antiretroviral drug regimen, consisting of lamivudine/zidovudine (AZT/3TC ...

FDA List Serve - Tentative approval of copackaged antiviral regim ... Mar 9, 2006
PharmaLive.com (press release), Administration (FDA) on March 6, 2006, granted tentative approval for a copackaged antiretroviral drug regimen, consisting of lamivudine/zidovudine fixed dose ...

Aurobindo to sell BMS' anti-AIDS drugs Mar 17, 2006
Reuters India, Food and Drug Administration had given a tentative approval to its version of an anti-AIDS combination drug consisting of Lamivudine, Zidovudine and Efavirenz.

Study finds no link between brain-penetrating antiretroviral drugs ... Mar 21, 2006
Aidsmap, Previous studies have shown that these are AZT (zidovudine, Retrovir), d4T (stavudine, Zerit), 3TC (lamivudine, Epivir), abacavir (Ziagen), nevirapine (Viramune ...

Aurobindo gets nod for FDC anti-AIDS drug Mar 9, 2006
Economic Times, ...tentative approval from the US Food and Drugs Administration for fixed dose combination (FDC) of anti-HIV/AIDS drugs lamivudine, zidovudine and efavirenz. ...

HAART failure rate halves in seven years Mar 24, 2006
Aidsmap, 46% in 2002). The most common nucleoside backbone remained AZT (zidovudine, Retrovir) and lamivudine (3TC, Epivir) throughout the study period. ...

US FDA Grants Traditional Approval for Gilead's Once-Daily HIV ... Mar 8, 2006
DG News Study 934, a phase 3 open-label trial comparing a once-daily regimen of Viread, Emtriva and efavirenz to twice-daily Combivir® (lamivudine/zidovudine) and once ...

Company Develops Better Tasting AIDS Solution to Help Treat Young ... Mar 7, 2006
Newsinferno.com, Zidovudine (Retrovir), an antiretroviral medication manufactured by both GSK (GlaxoSmithKline) and Cipla Pharmaceuticals, was the first drug approved to treat ...

FDA Grants Aurobindo Approval for Antiretroviral Therapy Mar 16, 2006
Kaiser network.org, The approval is for lamivudine 150 mg and zidovudine 300 mg fixed dose tablets packaged with efavirenz 600 mg tablets ( Dow Jones , 3/16). ...

US FDA Grants Traditional Approval for Gilead's Once-Daily HIV ... Mar 8, 2006
International News Service, 934, a Phase III open-label trial comparing a once-daily regimen of Viread, Emtriva and efavirenz to twice-daily Combivir(R) (lamivudine/zidovudine) and once ...

Traditional Approval of Viread and Truvada Mar 13, 2006
PharmaLive.com (press release), ...studies and the recently submitted Study 934, which compared the antiviral activity of tenofovir DF, emtricitabine, and efavirenz to zidovudine, lamivudine and ...

Aurobindo's another drug gets place in WHO's pre-qualification ... Dec 20, 2005
India Infoline.com, The other products included are Zidovudine tablets mg, Lamivudine tablets-150 mg & Lamivudine tablets-300 mg. This is one more milestone for the Company. ...

ICAAC: No added benefit from adding AZT to nevirapine to prevent ... Dec 18, 2005
Aidsmap, Adding a short course of AZT (zidovudine, Retrovir) to nevirapine (Viramune) therapy does not reduce the rate of mother-to-child transmission of HIV, according ...

Aurobindo’s Nevirapine included in WHO list Dec 12, 2005
Andhra Cafe, This is the company's fourth product to be included in the list along with others tablets Zidovudine tablets - 300 mg, Lamivudine tablets - 150 mg and ...

Number of Pills Affects Adherence to HIV Treatment Regimens Nov 30, 2005
PR Newswire (press release), HIV positive patients taking COMBIVIR achieved a >/= 95 percent adherence rate more than twice as often as patients taking lamivudine and zidovudine separately ...

Limb gat gains lower when switching from AZT to abacavir or ... Dec 15, 2005
Aidsmap, People switching from AZT- (zidovudine, Retrovir) containing anti-HIV regimens to either tenofovir- (Viread) or abacavir- (Ziagen) containing regimens are ...

Premature to say atazanavir not linked to fat loss, says ... Dec 12, 2005
Aidsmap, ...fat seen during HIV therapy is chiefly attributable to treatment with the nucleoside analogues d4T (stavudine, Zerit) and AZT (zidovudine, Retrovir), protease ...

Psychiatric Manifestations of HIV Infection and AIDS Dec 5, 2005
Psychiatric Times, The nucleoside reverse transcriptase inhibitor (NRTI) zidovudine (AZT, ZDV, Retrovir) was the earliest antiretroviral drug to be used in the management of HIV. ...

Number of Pills Affects Adherence to HIV Treatment Regimens Nov 30, 2005
PharmaLive.com (press release), Patients taking a fixed-dose combination of lamivudine (3TC) 150 mg and zidovudine (ZDV) 300 mg (COMBIVIR(R)) achieved >/= 95 percent adherence more than twice ...

Committee for Medicinal Products for Human Use Summary of Opinion ... Nov 18, 2005
PharmaLive.com (press release), 2005 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive scientific opinion for the medicinal product Lamivudine/zidovudine GSK film ...

Cheaper drugs brighten AIDS scene Nov 30, 2005
Daily News & Analysis, The cost of a common three-drug Antiretroviral Therapy (ART) regimen (Zidovudine, Lamivudine, Nevirapine) is about Rs 1300-1500 per month. ...

Pfizer releases further details of liver toxicity in maraviroc ... Dec 5, 2005
Aidsmap, ...study screening period, the patient first began receiving study drugs that included maraviroc 300 mg once daily (blinded study drug) and zidovudine/lamivudine. ...

Aurobindo’s Nevirapine included in WHO list Dec 11, 2005
Sify, The other products included are Zidovudine tablets - 300 mg, Lamivudine tablets - 150 mg and Lamivudine tablets - 300 mg, it said. ...

Aurobindo Pharma`s product included in WHO pre-qualification list Dec 12, 2005
Myiris.com, ...list. The other products included are Zidovudine tablets - 300 mg, Lamivudine tablets - 150 mg & Lamivudine tablets - 300 mg. Nevirapine ...

European Medicines Agency gives first positive opinions on ... Nov 20, 2005
Medical News Today (press release), The first products undergoing the new procedure are Lamivudine GSK 150 mg film-coated tablets and Lamivudine/Zidovudine GSK film-coated tablets, from Glaxo ...

Neurological side-effects of efavirenz mild and transient, study ... Dec 12, 2005
Aidsmap, ...efavirenz plus abacavir. All three arms also took AZT (zidovudine, Retrovir) and 3TC (lamivudine, Epivir). “Transient, subjective ...

Aurobindo Pharma's anti-AIDS drug selected by WHO Dec 12, 2005
domain-B, The others are 300mg-Zidovudine tablets, and the 150mg- and 300mg-Lamivudine tablets. Nevirapine is a key anti-retroviral (ARV), in the treatment of AIDS. ...

Ranbaxy Launches Two New Anti-Hiv Products In India On World Aids ... Dec 6, 2005
Medical News Today (press release), Virocomb-E is also a compliance pack and contains two fixed dose combination tablets of Lamivudine 150mg & Zidovudine 300mg and one tablet of Efavirenz 600mg. ...

HIV Virus Emerging Drug Resistant In UK, Prompting Fear Of A ... Nov 18, 2005
MedIndia, The currently available drugs are Zidovudine, Stavudine, Lamivudine, Abacavir, Indinavir, Efavirenz, Nevirapine and Didanosine. ...

The overuse of Tamiflu in treating avian flu Dec 2, 2005
Jakarta Post, Three or four antiretrovirals (ao zidovudine, didanosine, nefirapine, and indinavir) have been contributing modestly to the treatment of HIV-positive patients. ...

Ranbaxy to launch HIV drug combo in India Nov 30, 2005
United Press International ...of Efavirenz. Virocomb-E consists of two combination tablets of Lamivudine and Zidovudine and one tablet of Efavirenz. The packages ...

Switching from twice-daily Combivir to once-daily Truvada in ... Nov 23, 2005
Xagena.it, Data suggest that in HIV-infected treatment-experienced patients who switched from twice-daily Combivir ( Lamivudine 150 mg/Zidovudine 300 mg ) to once-daily ...

Ranbaxy announces new co-packaged triple ART combinations Dec 2, 2005
Aidsmap, Virocomb-E is also a compliance pack and contains two fixed dose combination tablets of lamivudine (3TC) 150mg and zidovudine (AZT) 300mg and one tablet of ...

Are safety labeling and safety warnings enough? Nov 23, 2005
Naples Sun Times, Asians. Scholars have spotlighted Zidovudine or AZT, used to treat AIDS, and not only because of its severe side effects. Prof. ...

AIDS awareness needs a boost Nov 30, 2005
Journal, He got on the AZT cocktail (the drug zidovudine used in combination with other antiviral drugs to help slow the progression of HIV), moved closer to home to be ...

*vwd/BUSINESS WIRE: 24-Wochen-Daten zur Wirkung von HIV-Patienten ... Nov 17, 2005
Vereinigte Wirtschaftsdienste, Data suggest that in HIV-infected treatment-experienced patients who switched from twice-daily Combivir(R) (lamivudine 150 mg/zidovudine 300 mg) to once-daily ...


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