vincristine
information and resources from the National Cancer Institute
NCI Thesaurus | vincristine
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis. NCI Thesaurus | vincristine
A natural alkaloid isolated from the plant Vinca rosea Linn. Vincristine binds irreversibly to microtubules and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spindle, thereby arresting tumor cells in metaphase. This agent also depolymerizes microtubules and may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin-dependent Ca++ -transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
Oncovin Eli Lilly Jul 10 1963
|
|
|
|
news articles
ICE Plus CAV Intensification Promising for High Risk Ewing’s ... Mar 31, 2006
Cancer Consultants (press release), ...an induction regimen of ifosfamide, carboplatin and etoposide (ICE) followed by intensification with cyclophosphamide, doxorubicin, and vincristine results in ...
Hana Biosciences to License Three Targeted Cancer Drug Candidates ... Mar 17, 2006
Genetic Engineering News, ...-- Hana plans to initiate pivotal trials for Marqibo(TM) (sphingosomal vincristine) in hematological malignancies in 2006. -- Sphingosomal ...
Glaxo Drug Approved For Preventing Flu and CytoDyn Applies for ... Mar 30, 2006
Financial News USA (press release), ...alkaloids. These drugs, which come from the Madagascar periwinkle (Catharanthus roseus), include vinblastine and vincristine. Idenix ...
Hana Biosciences to license cancer drugs Mar 17, 2006
BusinessWeek ...in stock in milestone payments, for global development and commercialization rights to chemotherapy drugs sphingosomal vincristine, sphingosomal vinorelbine ...
(PZ) CytoDyn Applies for Cancer Drug Trademark: Formaxycin Mar 27, 2006
Houston Chronicle, ...alkaloids. These drugs, which come from the Madagascar periwinkle (Catharanthus roseus), include vinblastine and vincristine. Both ...
Hana will license three cancer drugs for $11.5M Mar 17, 2006
San Francisco Business Times, ...a letter of intent to license development and sales rights for the chemotherapy drug candidates Marquibo (sphingosomal vincristine), sphingosomal vinorelbine ...
Inex Pharmaceuticals Licenses Three Targeted Chemotherapy Products ... Mar 17, 2006
Canada NewsWire (press release), INEX has granted Hana a worldwide license to develop and commercialize Marqibo(TM) (sphingosomal vincristine), INX-0125 (sphingosomal vinorelbine) and INX-0076 ...
CytoDyn Applies for Cancer Drug Trademark and EU Approves Pfizer ... Mar 28, 2006
Financial News USA (press release), These drugs, which come from the Madagascar periwinkle (Catharanthus roseus), include vinblastine and vincristine. Symyx Technologies, Inc. ...
Pixantrone Combination Regimen Produces High Rates of Complete ... Mar 22, 2006
PR Newswire (press release), ...curative bone marrow transplants." About the CHOP Regimen The CHOP chemotherapy regimen (a combination of cyclophosphamide, vincristine, prednisone and ...
Hana Paying Up To $42M For Inex’s Cancer Drugs Mar 17, 2006
BioWorld Online (subscription), ...up 30 cents. The compound farthest along is Marqibo (sphingosomal vincristine) for hematological malignancies. "Our target [with ...
CytoDyn to Develop Nonsynthetic Cancer Drug Mar 28, 2006
PrimeZone (press release), ...from the Madagascar periwinkle (Catharanthus roseus). These drugs include vinblastine and vincristine. Both have been used for many ...
High Dose Gleevec® and Low-Dose Chemotherapy Effective for ... Mar 17, 2006
Cancer Consultants (press release), Researchers from France have reported that high-dose Gleevec (imatinib) combined with vincristine and dexamethasone produced complete remissions (CR) in 28 of ...
High-Dose Gleevec® and Low-Dose Chemotherapy Effective for ... Mar 17, 2006
Cancer Consultants (press release), ...from France recently conducted a clinical trial to evaluate high-doses of Gleevec combined with low doses of the chemotherapy agent vincristine (Oncovin®) and ...
Pixantrone Combination Regimen Produces High Rates of Complete ... Mar 22, 2006
DG News The CHOP chemotherapy regimen (a combination of cyclophosphamide, vincristine, prednisone and doxorubicin) is the standard-of-care treatment for newly ...
Cell Therapeutics shows pixantrone data Mar 22, 2006
BusinessWeek ...the CHOP regimen. The CHOP regimen uses the drugs cyclophosphamide, vincristine, prednisone and doxorubicin. Cell Therapeutics replaced ...
Dr. Joseph Burchenal, 93; Chemotherapy Pioneer Mar 19, 2006
Los Angeles Times, ...turned into chemotherapy agents after researchers discovered that they suppressed the lymph system — and vinca alkaloids, such as vincristine, which were ...
The truth behind herbal drugs Mar 23, 2006
Express Pharma, Over the decades, there have been several instances of drugs sourced from herbal medicines like reseroine, vincristine and vinblatine. ...
US Study Fails to Confirm Benefits of Autologous Stem Cell ... Mar 14, 2006
Cancer Consultants (press release), This study called for VAD (vincristine, Adriamycin and dexamethasone) induction and cyclophosphamide/Neupogen® mobilization of peripheral blood stem cells in ...
Matrix Metalloproteinase Inhibitor Effective for Kaposi’s ... Mar 22, 2006
Cancer Consultants (press release), ...s sarcoma are initially treated with Doxil (liposomal doxorubicin) or combination chemotherapy with doxorubicin, bleomycin and vincristine, and approximately ...
CHOP Plus HAART Safe and Effective for AIDS-Related Lymphomas Mar 13, 2006
Cancer Consultants (press release), 2001. Patients were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in addition to concomitant HAART. ...
Select AIDS, cancer drugs to become cheaper Mar 2, 2006
Sify, ...arabinoside, danazol, daunorubicin HCL, etoposide, flutamide, ondansetron, pacitaxel, tamoxifen citrate, vinblastine sulphate, and vincristine, said an ...
FDA Approves Rituxan (Rituximab), the First Targeted B-Cell ... Mar 1, 2006
DG News Rituxan received FDA approval in February 2006 for the treatment of DLBCL in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone ...
High-Dose Therapy Does Not Improve Multiple Myeloma Outcome Mar 9, 2006
Cancerpage.com, They received melphalan and total-body irradiation and allotransplantation or standard chemotherapy with vincristine, carmustine, cyclophosphamide, melphalan ...
International Approvals: Rotarix, Hycamtin, Pulmicort HFA Mar 6, 2006
Medscape (subscription) Results of the first study showed topotecan to be similarly effective to a 3-drug regimen (cyclophosphamide, doxorubicin, and vincristine [CAV]) with respect ...
Doxil® in the VAD Regimen for Myeloma Confirmed Less Toxic Than ... Feb 28, 2006
Cancer Consultants (press release), A US multicenter trial has reported that a regimen of Doxil (pegylated liposomal doxorubicin), vincristine and dexamethasone is associated with less toxicity ...
Cancer not stopping student Mar 9, 2006
Tiffin Advertiser Tribune, He's taken weekly doses of vincristine and dactinomycin, plus cyclophosphamide every third Friday when he stays overnight in Toledo. ...
Thalidomide Not Associated with Survival Improvement in Multiple ... Mar 13, 2006
Cancer Consultants (press release), Traditionally patients receive induction therapy with VAD (vincristine, Adriamycin and dexamethasone) followed by single or tandem transplants with high-dose ...
Combination therapy improves AIDS-related lymphoma outcome Feb 26, 2006
EurekAlert (press release), They are treated with chemotherapy, often consisting of a multi-drug regimen using cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP). ...
Combo Therapy Fights AIDS-Linked Lymphoma Feb 27, 2006
Forbes 72 HIV patients with AIDS-related lymphoma treated with a multi-drug chemotherapy called CHOP (cylcophosphamide, doxorubicin, vincristine, and prednisone) and ...
Patients with Unfavorable Risk Hodgkin’s Lymphoma May Not ... 21 Dec 2005
Cancer Consultants (press release), BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone) is a more intensive regimen that has also been ...
Six Cycles of Bi-Weekly R-CHOP Standard for Elderly with Diffuse ... Dec 19, 2005
Cancer Consultants (press release), ...s Lymphoma Study Group (DSHNHL) have reported that 6-cycles of Rituxan® (rituximab) and CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) given ...
Diagnostic Errors in Medical Treatments (I) Dec 12, 2005
This Day (subscription), In the second scenario, a doctor participating in a General Practice vocational training scheme was asked to give vincristine to a three-year-old child with ...
Zevalin Used in Abbreviated Chemotherapy Regimen Shows Efficacy ... Dec 16, 2005
DG News CHOP-R comprises a combination of rituximab (Mabthera(R)), cyclophosphamide, doxorubicin, (Adriamycin(R)), vincristine (Oncovin(R)) and prednisolone. ...
Rituximab maintenance therapy dramatically improves survival in ... Dec 13, 2005
RxPG NEWS, 465 patients with relapsed and refractory indolent NHL were randomised to receive either 3-weekly cyclophosphamide, doxorubicin, vincristine, and prednisone ...
VELCADE(R) (bortezomib) for Injection Continues to Show Impressive ... Dec 12, 2005
PR Newswire (press release), Rituximab (abstract #491) Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and prednisone ...
VELCADE (bortezomib) for Injection Continues to Show Impressive ... Dec 13, 2005
PharmaLive.com (press release), Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) plus rituximab for the ...
Maintenance therapy with RITUXAN(R) dramatically improves survival Dec 12, 2005
CNW Telbec (Communiqués de presse), ...patients with relapsed and refractory indolent NHL were randomised to receive either three- weekly cyclophosphamide, doxorubicin, vincristine, and prednisone ...
Phase II Clinical Results Indicate That MyVax(R) Personalized ... Dec 12, 2005
PR Newswire (press release), ...or circumstances after the date hereof. (1) Chemotherapy regimen containing cyclophosphamide, adriamycin, vincristine, prednisone.
Intensive Chemotherapy Regimen Shows Promise for Germ Cell Tumors Dec 5, 2005
Cancer Consultants (press release), This regimen consisted of cycles of cisplatin, vincristine, bleomycin, and carboplatin, followed by one cycle of vincristin and bleomycin and three cycles of ...
Hycamtin® receives positive opinion in Europe for treatment of ... Nov 28, 2005
Medical News Today (press release), The first Study (protocol 090) compared the safety and efficacy of HYCAMTIN to the triple combination cyclophosphomide, doxorubicin and vincristine (CAV) in ...
Rituxan® Plus CHOP Improves Outcomes of Patients with Follicular ... Nov 22, 2005
Cancer Consultants (press release), Researchers from Germany have reported that adding Rituxan (rituximab) to CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) improves outcomes of ...
R-CHOP Improves Outcomes as Initial Therapy in Follicular Lymphoma Nov 28, 2005
Cancer Consultants (press release), Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves outcome ...
Scientific Research Proves Xanthones Kill Cancer Cells and May ... Nov 25, 2005
PR Web (press release), ...over 40 Xanthones found in the Mangosteen fruit), was tested against six chemotherapy agents (5 Flouraicil, cisplatin, vincristine, methotrexate, mitoxantrone ...
Journal of the American Podiatric Medical Association Nov 29, 2005
Journal of the American Podiatric Medical Association 73% of cases. Agents such as vinblastine, vincristine, and bleomycin are prescribed because of their limited toxicity. 3. A 73-year ...
Science & Technology: BIOPROSPECTING IN THE REGION Dec 3, 2005
Island Business, For example, the chemicals vinblastin and vincristine, now used in anti-leukemia drugs, were discovered in the ornamental rosy periwinkle (Catharanthus roseus ...
Long-term remission after autologous peripheral blood stem cell ... Nov 24, 2005
Nature.com (subscription), She achieved a complete remission (CR) after five courses of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) therapy. ...
|
|
