trimethoprim-sulfamethoxazole
information and resources from the National Cancer Institute
trimethoprim-sulfamethoxazole
A synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as co-trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial dihydrofolate synthetase. trimethoprim-sulfamethoxazole
A synthetic combination of two antibacterial agents, trimethoprim and sulfamethoxazole. This synergistic combination, also known as co-trimoxazole, inhibits two sequential steps in the bacterial metabolism of folic acid. Trimethoprim is a pyrimidine inhibitor of dihydrofolate reductase; sulfamethoxazole is a sulfamide inhibitor of bacterial dihydrofolate synthetase.
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news articles
Highlights From MMWR: Outbreaks of MRSA Infection in Newborns and ... Mar 31, 2006
Medscape (subscription) Other potential agents such as tetracyclines or trimethoprim-sulfamethoxazole are contraindicated or not recommended in newborns. ...
Immtech Sets Trial for Pneumonia Drug Mar 6, 2006
MSN Money Immtech's drug is administered twice a day for 14 days, as opposed to the currently standard trimethoprim-sulfamethoxazole tablets, which are administered ...
Emergence of Community-Acquired Methicillin-Resistant ... Mar 6, 2006
Annals of Internal Medicine No MRSA USA 300 isolate was resistant to trimethoprim–sulfamethoxazole or vancomycin, while most were resistant to erythromycin in addition to ß-lactams. ...
What you should know about Salmonella Mar 9, 2006
Food Consumer, ...necessary unless the infection spreads from the intestines, then it can be treated with ampicillin, gentamicin, trimethoprim/sulfamethoxazole, or ciprofloxacin ...
Pneumocystis Pneumonia (PCP) In Patients With HIV/AIDS - Immtech ... Mar 6, 2006
Medical News Today (press release), ...tolerability of DB289, when administered as 100 mg tablets twice daily for 14 days versus the standard of care, which is trimethoprim-sulfamethoxazole (TMP-SMX ...
C-diff a growing menace Dec 1, 2005
Toronto Star, She had been treated about three months earlier with an antibiotic, trimethoprim-sulfamethoxazole. Ten others among had taken clindamycin. ...
Deadly Bacterial Illness May Be Spreading Dec 1, 2005
CBS News She had been treated about three months earlier for a urinary tract infection with an antibiotic, trimethoprim-sulfamethoxazole. ...
Deadly bacteria spreads beyond high-risk group Dec 1, 2005
Washington Times, But the pregnant woman who died had taken a common antibiotic known as trimethoprim sulfamethoxazole three months earlier to treat a urinary tract infection.
CDC: Deadly 'C-diff' bacteria is spreading Dec 1, 2005
Winston-Salem Journal, She had been treated about three months earlier for a urinary-tract infection with an antibiotic, trimethoprim-sulfamethoxazole.
CDC: Severe Clostridium difficile--associated disease increases Dec 1, 2005
Food Consumer, Her only antimicrobial exposure during the preceding year was trimethoprim-sulfamethoxazole (for a urinary tract infection) approximately 3 months before ...
FDA Approves New Indication for Avelox (moxifloxacin HCl) for ... Nov 30, 2005
DG News MIC greater than or equal to 2 mcg/mL), second generation cephalosporins, eg, cefuroxime, macrolides, tetracyclines and trimethoprim/sulfamethoxazole. ...
Pfizer releases further details of liver toxicity in maraviroc ... Dec 5, 2005
Aidsmap, Seven weeks prior to study drug initiation, isoniazid (INH) and cotrimoxazole (trimethoprim-sulfamethoxazole) were started for primary prophylaxis of HIV ...
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