trabectedin

trabectedin information and resources from the National Cancer Institute

NCI Thesaurus | trabectedin

A tetrahydroisoquinoline alkaloid isolated from the marine tunicate Ecteinascidia turbinate. Trabectedin, also known as ecteinascidin 743 (ET743), exhibits potent tumor cytotoxicity by prolonging the G2-M phase of the cell cycle. This agent interacts with the transcription-coupled nucleotide excision repair machinery to induce lethal DNA strand breaks. NCI Thesaurus | trabectedin

A tetrahydroisoquinoline alkaloid isolated from the marine tunicate Ecteinascidia turbinate. Trabectedin, also known as ecteinascidin 743 (ET743), exhibits potent tumor cytotoxicity by prolonging the G2-M phase of the cell cycle. This agent interacts with the transcription-coupled nucleotide excision repair machinery to induce lethal DNA strand breaks.

PharmaMar Confirms Intention to Submit MAA Dec 19, 2005
APA OTS (Pressemitteilung), ...relevant therapeutic area. About YONDELIS YONDELIS(R) (trabectedin), is PharmaMar's most advanced compound in development. It was ...

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