sulindac
information and resources from the National Cancer Institute
NCI Thesaurus | sulindac
A sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death. NCI Thesaurus | sulindac
A sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death.
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news articles
Preventing Breast Cancer Nov 23, 2005
KOLD-TV, ...cancer. the purpose of the study is to see if sulindac a drug used by arthritis patients can also be used to prevent breast cancer. ...
Government backs down on PBS cuts Nov 29, 2005
AustralianDoctor.com (subscription), The addition of diazepam, diclofenac, ibuprofen, indomethacin, naproxen, nitrazepam, oxazepam, sulindac and temazepam to the palliative care section of the ...
Columbia researchers find herbal extract aids in fight against ... Nov 27, 2005
Newstarget.com, COX inhibitors have also shown value for prostate cancer patients, but data from recent trials of selective COX-2 inhibitors such as sulindac (Clinoril®) and ...
Preventing Breast Cancer Nov 23, 2005
KOLD-TV, ...cancer. the purpose of the study is to see if sulindac a drug used by arthritis patients can also be used to prevent breast cancer. ...
Government backs down on PBS cuts Nov 29, 2005
AustralianDoctor.com (subscription), The addition of diazepam, diclofenac, ibuprofen, indomethacin, naproxen, nitrazepam, oxazepam, sulindac and temazepam to the palliative care section of the ...
Columbia researchers find herbal extract aids in fight against ... Nov 27, 2005
Newstarget.com, COX inhibitors have also shown value for prostate cancer patients, but data from recent trials of selective COX-2 inhibitors such as sulindac (Clinoril®) and ...
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