rosiglitazone

rosiglitazone information and resources from the National Cancer Institute

NCI Thesaurus | rosiglitazone

An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Rosiglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. NCI Thesaurus | rosiglitazone

An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Rosiglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.



news articles



Ask us here and we'll Mar 28, 2006
Moneycontrol.com, In recent times, glitazones (rosiglitazone and pioglitazone) have been launched to treat increasing prevalence of insulin resistance in Type - II diabetes. ...

Improving Diabetes Control May Improve Memory Mar 8, 2006
Diabetes Self Management ...memory. Then they randomly assigned them to take, along with the metformin, either rosiglitazone (brand name Avandia) or a glyburide. ...

Joslin Researchers Reveal Mechanisms Behind Class of Oral Agents ... Mar 9, 2006
AScribe ...diabetes. Current US Food and Drug Administration-approved agents are known as Actos (pioglitazone) and Avandia (rosiglitazone). ...

Tips for Helping People With Diabetes Live a Healthy Life, From ... Mar 23, 2006
TMCnet Guide, diabetes treatments that work include the use of blood glucose lowering drugs such as metformin (Fortmet, Glucophage), rosiglitazone (Avandia), and ...

Latest diabetic medications more costly, but users have fewer ... Mar 22, 2006
News-Medical.net, TZDs (pioglitazone and rosiglitazone, brand names Actos and Avandia, respectively), were approved by the Food and Drug Administration in the late 1990s. ...

Are newer diabetic meds worth it? Mar 23, 2006
myDNA.com, TZDs (pioglitazone/brand name Actos and rosiglitazone/brand name Avandia) were approved by the US Food and Drug Administration in the late 1990s. ...

Data Analysis Showed VYTORIN(R) (Ezetimibe/Simvastatin) ... Mar 13, 2006
International News Service, In a multicenter, double-blind, 24-week trial, 214 patients with type 2 diabetes mellitus treated with thiazolidinediones (rosiglitazone or pioglitazone) for a ...

New Combination Pill Approved for Type 2 Dec 7, 2005
Diabetes Self Management Made by GlaxoSmithKline, Avandaryl is a combination of rosiglitazone (brand name Avandia) and glimepiride (Amaryl). It’s approved ...

Glitazone link to macular oedema explored Dec 15, 2005
Reuters ...comes after the EMEA received reports of cases of macular oedema in patients taking GlaxoSmithKline's Avandia/Avandamet (rosiglitazone) and Takeda and Lilly's ...

FDA Approvals: Avelox, Avandaryl, Trileptal Dec 1, 2005
Medscape (subscription) Dec. 1, 2005 — The US Food and Drug Administration (FDA) has approved rosiglitazone maleate plus glimepiride tablets for first- and second-line use in the ...

Sensex snaps 5-day rally; rupee climbs Dec 14, 2005
Gulf Times, The company won approval to sell 2-milligram, 4-milligram and 8-milligram tablets of rosiglitazone maleate in the US, the drug regulator said in an e-mailed ...

Diabetes drugs now covered Nov 23, 2005
Victoria News, Avandia (rosiglitazone) and Actos (pioglitazone) will benefit certain patients whose diabetes is not effectively managed by conventional oral treatments, the ...

Takeda's Actos(R) (pioglitazone) Helps to Prevent Further Heart ... Nov 18, 2005
PR Newswire UK (press release), ...were observed with metformin and gliclazide.(3),(4) In a large, double-blind clinical trial comparing pioglitazone to rosiglitazone, pioglitazone significantly ...

La Merie Business Intelligence PR: Competition is needed in the ... Nov 28, 2005
PharmaLive.com (press release), BARCELONA, Spain, November 28, 2005 - The two peroxisome proliferator-activated receptor (PPAR) gamma agonists pioglitazone and rosiglitazone approved for ...

New Diabetes Drug Approval Questioned Dec 1, 2005
Georgia Straight, Avandia, the trade name of rosiglitazone, is made by GlaxoSmithKline. Actos, the trade name of pioglitazone, is made by Eli Lilly. ...

KineMed Presents Body Water Test as a Potential New 'Gold Standard ... Nov 18, 2005
Yahoo! News (press release) ...resistance in animal models due to both genetic and dietary factors, and to quantify the insulin sensitizing response to drugs (rosiglitazone and metformin). ...


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