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recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
information and resources from the National Cancer Institute
NCI Thesaurus | recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and activate a cytotoxic T-cells response against CEA- and MUC-1-expressing tumor cells. NCI Thesaurus | recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and activate a cytotoxic T-cells response against CEA- and MUC-1-expressing tumor cells.
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recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
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