recombinant tissue plasminogen activator

recombinant tissue plasminogen activator information and resources from the National Cancer Institute

NCI Thesaurus | recombinant tissue plasminogen activator

A recombinant therapeutic agent which is chemically identical to or similar to endogenous tissue plasminogen activator (tPA). tPA is a serine protease which converts plasminogen to plasmin, a fibrinolytic enzyme. Upon administration, recombinant tPA increases plasmin enzymatic activity, resulting in hyperfibrinolysis and potential dissolution of a thrombus or embolism. NCI Thesaurus | recombinant tissue plasminogen activator

A recombinant therapeutic agent which is chemically identical to or similar to endogenous tissue plasminogen activator (tPA). tPA is a serine protease which converts plasminogen to plasmin, a fibrinolytic enzyme. Upon administration, recombinant tPA increases plasmin enzymatic activity, resulting in hyperfibrinolysis and potential dissolution of a thrombus or embolism.



news articles



Axaron Bioscience AG Receives Frost & Sullivan's 2005 Technology ... Nov 10, 2005
Yahoo! News (press release) In comparison to recombinant tissue plasminogen activator (rt-PA), G-CSF's value in the treatment of acute ischemic stroke lies in its multiple mechanisms-of ...

Location, Location, Location: Angiography Discerns Early MR ... Oct 25, 2005
Am J Neuroradiology (subscription) ...date has taken thrombus composition as being reflected by GRE (and FLAIR) images and its role for rtPA [recombinant tissue plasminogen activator] response into ...

2005 ASNR Gold Medal Award Winner Oct 21, 2005
Am J Neuroradiology (subscription) Dr. Wolpert was the lead neuroradiological investigator in one of the first studies on the value of intravenous recombinant tissue plasminogen activator in the ...


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