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recombinant fowlpox GM-CSF vaccine
recombinant fowlpox GM-CSF vaccine
information and resources from the National Cancer Institute
NCI Thesaurus | recombinant fowlpox GM-CSF vaccine
A cancer vaccine consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of fowlpox-sargramostim may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.NCI Thesaurus | recombinant fowlpox GM-CSF vaccine
A cancer vaccine consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of fowlpox-sargramostim may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells.
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recombinant fowlpox GM-CSF vaccine
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