prednisolone
information and resources from the National Cancer Institute
prednisolone
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. prednisolone
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations.
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news articles
BioMarin Announces Closing of $295 Million Concurrent Public ... Mar 30, 2006
PR Newswire (press release), Additionally, BioMarin has rights to receive payments and royalties related to Orapred(R) (prednisolone sodium phosphate oral solution). ...
Targeting the inflamed synovium Mar 28, 2006
EurekAlert (press release), In one animal model experiment, liposome-encapsulated prednisolone was reported to achieve the effects equivalent to 10-fold higher doses of the free drug. ...
CT scans rarely cause allergic reactions Mar 21, 2006
Electric New Paper, An AH spokesman said: 'Patients with a history of drug allergies do not need prednisolone unless they are specifically allergic to the contrast and had ...
When a single pill can kill Mar 21, 2006
Electric New Paper, The doctor in Mr Dorai's ward felt he did not need to be given the medication - the drug prednisolone - but the radiologist refused to proceed without it. ...
BioMarin and Alliant Pharmaceuticals Announce North American ... Mar 15, 2006
PR Newswire (press release), ...they have entered into a licensing and acquisition agreement pertaining to exclusive North American rights to the Orapred(R) (prednisolone sodium phosphate ...
When arthritis strikes children Mar 27, 2006
Washington Times, Her first flare of uveitis was caught at age 4 during a monthly eye examination. Sarah uses prednisolone acetate, steroid eye drops, five time a day. ...
BioMarin and Alliant in licensing deal Mar 17, 2006
Pharmaceutical Business Review Orapred is the leading brand of liquid prednisolone sodium phosphate used to treat exacerbations of asthma and other inflammatory diseases and conditions in ...
BioMarin’s Shares Move On Phenoptin Phase III Success Mar 16, 2006
BioWorld Online (subscription), ...filings and a potential launch of Phenoptin, it made sense for BioMarin to license out North American rights to the Orapred (prednisolone sodium phosphate ...
Committee for Medicinal Products for Human Use Post-authorisation ... Mar 24, 2006
PharmaLive.com (press release), Taxotere (docetaxel) in combination with prednisone or prednisolone is indicated for the treatment of patients with hormone refractory metastatic prostate ...
BioMarin and Serono Announce Positive Results From Phase 3 ... Mar 15, 2006
PR Newswire (press release), ...wholly developed and commercialized by BioMarin, Aldurazyme(R) (laronidase) for mucopolysaccharidosis I (MPS I), and Orapred(R) (prednisolone sodium phosphate ...
AAEP task force recommends medication rules for sales Dec 14, 2005
Thoroughbred Times, ...s recommendations, sales companies would allow only one non-steroidal anti-inflamatory drug and one cortico-steroid (excluding methyl-prednisolone acetate) to ...
Zevalin Used in Abbreviated Chemotherapy Regimen Shows Efficacy ... Dec 16, 2005
DG News CHOP-R comprises a combination of rituximab (Mabthera(R)), cyclophosphamide, doxorubicin, (Adriamycin(R)), vincristine (Oncovin(R)) and prednisolone. ...
BioMarin to Host Research and Development Day on Tuesday, December ... Nov 22, 2005
PR Newswire (press release), ...wholly developed and commercialized by BioMarin, Aldurazyme(R) (laronidase) for mucopolysaccharidosis I (MPS I), and Orapred(R) (prednisolone sodium phosphate ...
Long-term remission after autologous peripheral blood stem cell ... Nov 24, 2005
Nature.com (subscription), She achieved a complete remission (CR) after five courses of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) therapy. ...
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