pioglitazone hydrochloride
information and resources from the National Cancer Institute
NCI Thesaurus | pioglitazone hydrochloride
The hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. NCI Thesaurus | pioglitazone hydrochloride
The hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.
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news articles
Lilly Reports $.73 EPS and 10 Percent Sales Growth in the Third ... Oct 20, 2005
PR Newswire (press release), Actos(R) (pioglitazone hydrochloride, Takeda), Takeda Alimta(R) (pemetrexed, Lilly) Cialis(R) (tadalafil, ICOS), Lilly ICOS LLC Cymbalta(R) (duloxetine ...
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