phenoxodiol
information and resources from the National Cancer Institute
NCI Thesaurus | phenoxodiol
A synthetic flavonoid derivative. Phenoxodiol activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), and disrupts FLICE inhibitory protein (FLIP) expression, resulting in tumor cell apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex, thereby preventing DNA replication and resulting in tumor cell death. NCI Thesaurus | phenoxodiol
A synthetic flavonoid derivative. Phenoxodiol activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), and disrupts FLICE inhibitory protein (FLIP) expression, resulting in tumor cell apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex, thereby preventing DNA replication and resulting in tumor cell death.
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news articles
Yale Researchers Find Phenoxodiol Restores Sensitivity to ... Mar 29, 2006
DG News WASHINGTON, DC, and SYDNEY, AUSTRALIA -- March 29, 2006 -- Phenoxodiol, an investigational anti-cancer drug that is being studied by leading researchers at Yale ...
Yale Researchers Find Phenoxodiol Restores Sensitivity to ... Mar 29, 2006
PR Newswire (press release), WASHINGTON and SYDNEY, Australia, March 29 /PRNewswire-FirstCall/ -- Phenoxodiol, an investigational anti-cancer drug that is being studied by leading ...
Positive trial for Marshall Edwards anticancer drug Mar 30, 2006
Pharmaceutical Business Review Marshall Edwards' investigational anticancer drug phenoxodiol has been found, in a phase II study, to be active and to restore platinum drug sensitivity to ...
Marshall Edwards, Inc. to Present at the CIBC World Markets Annual ... Mar 31, 2006
PR Newswire (press release), ...(Nasdaq: MSHL) has licensed rights from Novogen Limited (Nasdaq: NVGN) to bring phenoxodiol to market globally. Marshall Edwards, Inc. ...
Australian Stocks Advance, Led by BHP, Newcrest on Copper, Gold Mar 29, 2006
Bloomberg ...(MSHL US) received positive feedback from Yale researchers who found its drug Phenoxodiol restores sensitivity to chemotherapy in women suffering from ovarian ...
(PRN) - Understanding Adoption Rates of Wound Care products ... Mar 29, 2006
Bolsamania.com, ...[+]. (PRN) - Yale Researchers Find Phenoxodiol Restores Sensitivity to Chemotherapy in Some Women With Ovarian, Fallopian Tube or Primary Peritoneal Cancer, in ...
Data From Novogen Inflammatory Bowel Disease Drug Phase I Clinical ... Mar 2, 2006
Yahoo! News (press release) The Company is developing a range of therapeutics across the fields of oncology, cardiovascular disease and inflammatory diseases and phenoxodiol, its lead anti ...
New Clinical Study of Phenoxodiol as Chemo-sensitizer for ... Nov 28, 2005
PR Newswire (press release), ...announced today plans for a Phase Ib/IIa clinical study of the investigational anti-cancer drug, phenoxodiol in combination with docetaxel for women with ...
Phenoxodiol - docetaxel combination for women with recurrent ... Dec 5, 2005
News-Medical.net, A clinical study of ovarian cancer initiated by investigators at Yale School of Medicine will combine the anti-cancer drug phenoxodiol with docetaxel for women ...
Researchers Report That Phenoxodiol Produces Anti-Cancer Responses ... Nov 17, 2005
PR Newswire (press release), Masoud Azodi, Peter Schwartz, Michael Kelly, Thomas Rutherford and Gil Mor, indicates continuing confidence that the investigational drug phenoxodiol has the ...
Phenoxodiol Delays Tumor Progression in Late-Stage Hormone ... Nov 17, 2005
PR Newswire (press release), ...study presented today at the International Conference on Molecular Targets and Cancer Therapeutics in Philadelphia shows that phenoxodiol significantly delays ...
New Drug Fights Two Cancers Nov 21, 2005
Ivanhoe, ...(Ivanhoe Newswire) -- The experimental drug phenoxodiol shows promise in fighting cancers of the prostate and cervix, according to two new studies. ...
Novogen's subsidiary, Marshall Edwards, Inc., announces cervical ... Nov 18, 2005
Biotech Intelligence (press release), ...at a meeting of the American Association for Cancer Research in Philadelphia, indicates continuing confidence that the experimental drug phenoxodiol has the ...
Promising Results for Cervical Cancer Patients Nov 17, 2005
All Headline News The data indicates continuing confidence that the drug phenoxodiol has the potential to change management options for this highly aggressive gynecological ...
(PRN) - Engate Offers Reputation-Based Connection Management ... Nov 28, 2005
Bolsamania.com, ...(PRN) - New Clinical Study of Phenoxodiol as Chemo-sensitizer for Docetaxel in Ovarian Cancer Commences at Yale University School of Medicine ... [+. ...
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