paclitaxel poliglumex
information and resources from the National Cancer Institute
NCI Thesaurus | paclitaxel poliglumex
The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization, thus interfering with normal mitosis. NCI Thesaurus | paclitaxel poliglumex
The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization, thus interfering with normal mitosis.
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news articles
Cell Therapeutics, Inc. CEO Talks About Lung Cancer Treatments for ... Mar 9, 2006
PharmaLive.com (press release), XYOTAX (paclitaxel poliglumex) is a biologically-enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable ...
Pivotal Trial to Evaluate Comparative Effectiveness of XYOTAX to ... Dec 6, 2005
PharmaLive.com (press release), ...(CTI) today announced plans to initiate a clinical trial in women of XYOTAX (paclitaxel poliglumex) versus paclitaxel chemotherapy for the treatment of PS2 ...
Pivotal Trial to Evaluate Comparative Effectiveness of XYOTAX(TM) ... Dec 6, 2005
PR Newswire (press release), ...(CTI) (Nasdaq and MTAX: CTIC) today announced plans to initiate a clinical trial in women of XYOTAX (paclitaxel poliglumex) versus paclitaxel chemotherapy for ...
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