paclitaxel

paclitaxel information and resources from the National Cancer Institute

NCI Thesaurus | paclitaxel

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). NCI Thesaurus | paclitaxel

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2).

Taxol

First line ovarian cancer with 3 hour infusion.

Bristol-Myers Squibb Jun 20 2000

Taxol

For first-line therapy for the treatment of advanced carcinoma of the ovary in combination with cisplatin.

Bristol-Myers Squibb Apr 09 1998

Taxol

For the adjuvant treatment of node-positive breast cancer administered sequentially to standard doxorubicin-containing combination therapy.

Bristol-Myers Squibb Oct 25 1999

Taxol

for use in combination with cisplatin, for the first-line treatment of non-small cell lung cancer in patients who are not candidates for potentially curative surgery and/or radiation therapy.

Bristol-Myers Squibb Jun 30 1998

Taxol

New dosing regimen for patients who have failed initial or subsequent chemotherapy for metastatic carcinoma of the ovary

Bristol-Myers Squibb Jun 22 1994

Taxol

second line therapy for AIDS related Kaposi's sarcoma.

Bristol-Myers Squibb Aug 04 1997

Paxene

treatment of advanced AIDS-related Kaposi's sarcoma after failure of first line or subsequent systemic chemotherapy

Baker Norton Pharmaceuticals, Inc Dec 24 1997

Taxol

Treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline unless clinically contraindicated.

Bristol-Myers Squibb Apr 13 1994

Taxol

Treatment of patients with metastatic carcinoma of the ovary after failure of first-line or subsequent chemotherapy.

Bristol-Myers Squibb Dec 29 1992



news articles



Subscribe to Opto Circuits FPO for 1-2 yrs: India Infoline 01 Apr 2006
Moneycontrol.com, FY08. EuroCOR recently received CE (European Conformity) mark approval for its TAXCOR Paclitaxel eluting coronary stent system. ...

Blue Membranes Approaches the US and Japan markets 01 Apr 2006
Yahoo! News (press release) This collaboration resulted in the development of a paclitaxel-eluting cobalt chromium coronary stent with a carbon-based nano-composite coating that is ...

Paclitaxel combined with bevacizumab prolongs progression free ... Mar 23, 2006
Innovations-Report, ...randomised clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin) in combination with paclitaxel (Taxol) survived ...

Paclitaxel-Releasing Stent More Effective Than Intra-Coronary ... Mar 17, 2006
DG News CHICAGO, IL -- MARCH 17, 2006 -- Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary ...

Paclitaxel-Bevacizumab Combination Prolongs Progression-Free ... Mar 23, 2006
DG News ...with advanced breast cancer have a significantly longer progression-free survival when bevacizumab (Avastin) is added to their paclitaxel (Taxol), according to ...

ACC Data Show Numerical Trend Favoring TAXUS(R) Coronary Stent ... Mar 29, 2006
PR Newswire (press release), ...clinical trials and registries offered data that indicated a positive numerical trend in the performance of the TAXUS(R) Express2(TM) paclitaxel-eluting stent ...

Paclitaxel Combined With Bevacizumab Prolongs Progression Free ... Mar 25, 2006
Medical News Today (press release), ...clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin®) in combination with paclitaxel (Taxol®) survived without ...

Stents that release the drug paclitaxel to treat stenosis more ... Mar 13, 2006
News-Medical.net, Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent ...

Paclitaxel-Eluting Stents Top Angioplasty for Preventing ... Mar 13, 2006
DG News ATLANTA, GA -- March 13, 2006 -- The treatment of bare-metal in-stent restenotic lesions with paclitaxel-eluting stents instead of angioplasty followed by ...

CORRECTING and REPLACING Sonus Pharmaceuticals Highlights 2005 ... Mar 16, 2006
International News Service, The discussion will include an overview of the progress to date and future plans for TOCOSOL Paclitaxel, the Company's lead anti-cancer product candidate. ...

Boston Scientific Reveals TAXUS Receives Favorable ACC Data With ... Mar 29, 2006
Trading Markets, ...offered data that indicated a positive numerical trend in the performance of the TAXUS® Express2(TM | charts | news | Powerrating) paclitaxel-eluting stent ...

Gemzar®/Paraplatin® Followed by Taxol®/Paraplatin® as Initial ... Mar 28, 2006
Cancer Consultants (press release), Oncology, the chemotherapy regimen consisting of Gemzar® (gemcitabine) plus Paraplatin® (carboplatin) followed by Taxol® (paclitaxel) plus Paraplatin ...

Shareholders approve acquisition of Guidant Mar 31, 2006
Pioneer Press, ...tissue in the stent. Boston Scientific's Taxus stent uses a different drug, paclitaxel, to achieve the same goal. Abbott would own ...

Gemzar®/Platinol® Superior to VePesid®/Platinol® in Non-Small ... Mar 29, 2006
Cancer Consultants (press release), Paclitaxel plus carboplatin is one of the most commonly used chemotherapy regimens in the treatment of NSCLC in the US and Europe. ...

CytImmune Sciences Receives Phase I SBIR Grant for Next-Generation ... Mar 30, 2006
PharmaLive.com (press release), The first of these new combination drugs, termed CYT-21001, will consist of TNF and a thiolated paclitaxel analog bound to the surface of 27 nm pegylated ...

Sonus Pharmaceuticals to Present at WBBA Invest Northwest(TM) ... Mar 16, 2006
International News Service, The Company's lead oncology product candidate is TOCOSOL(R) Paclitaxel, a new formulation of the widely prescribed anti-cancer drug paclitaxel. ...

Angiotech Pharma Says Trials Reveal Positive Numerical Trend Of ... Mar 29, 2006
Trading Markets, ...several clinical trials and registries offered data that indicated a positive numerical trend in the performance of the TAXUS Express2 paclitaxel-eluting stent ...

SD Pharmaceuticals Inc. Reports Positive Efficacy Data on Its Non ... Mar 24, 2006
Genetic Engineering News, SD Pharmaceuticals Inc. (SDP) today announced that it has completed a battery of pre-clinical studies on its novel nano-emulsion formulation of paclitaxel. ...

Sonus Pharmaceuticals to Release Fourth Quarter and Full Year 2005 ... Mar 2, 2006
Genetic Engineering News, 4:30 PM EST, management will host a conference call to provide a company update, including a review of the progress with TOCOSOL(R) Paclitaxel, the Company's ...

Addition of Ellence® to Standard Chemotherapy Does Not Improve ... Mar 2, 2006
Cancer Consultants (press release), ...addition of the chemotherapy agent Ellence® (epirubicin) to the standard chemotherapy regimen of Paraplatin® (carboplatin) and Taxol® (paclitaxel) does not ...

Angiotech Pharmaceuticals, Inc. announces results for the quarter ... Mar 2, 2006
CNW Telbec (Communiqués de presse), ...fully taxable in 2005, an increase in certain litigation expenditures and a decrease in royalty revenue derived from the sale of paclitaxel-eluting coronary ...

Sonus Pharma hits new 52-week high Mar 17, 2006
BusinessWeek Sonus booked revenue of $8.3 million for the fourth quarter and the year, solely from development revenue for cancer drug Tocosol Paclitaxel from marketing ...

Sonus Pharmaceuticals Narrows Loss in the Fourth Quarter Mar 16, 2006
Canadian Business, The company's revenue stems from its agreement with drug maker Schering AG regarding Sonus' development and testing of Tocosol Paclitaxel, a treatment for ...

Sonus Pharma Q4 Net Loss Narrows On Research Funding - Update Mar 16, 2006
Trading Markets, ...in the fourth quarter, $7.1 million was related to research and development funding for work completed on the Phase 3 trial for TOCOSOL Paclitaxel and related ...

Bayer receives Swiss approval for advanced kidney cancer drug ... Mar 29, 2006
Forbes Bayer recently initiated phase III trials of the drug to treat non-small cell lung cancer in combination with chemotherapeutic agents carboplatin and paclitaxel ...

Pro-Pharmaceuticals Completes Patient Enrollment in Stage 1 of ... Mar 30, 2006
Genetic Engineering News, ...studies with its lead product candidate, DAVANAT(R), in combination with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ...

Boston Scientific: TAXUS Stent Shows Positive Results In Complex ... Mar 29, 2006
Trading Markets, The STENT Registry showed nine-month results from 5,566 patients who received either a TAXUS Express2 paclitaxel-eluting coronary stent system or a Cypher ...

ArQule to Present Phase 1 Monotherapy Data with ARQ 501 at AACR ... Mar 30, 2006
Genetic Engineering News, ...trials in leiomyosarcoma and head and neck cancer, as well as combination therapy trials with gemcitabine in pancreatic cancer and with paclitaxel in ovarian ...

Opponents help one another after accident Mar 28, 2006
Central Michigan Life, ...news-medical.net. Taxol is known as “paclitaxelâ€? and is a top-selling drug used to fight ovarian and breast cancers. It can ...

Yale Researchers Find Phenoxodiol Restores Sensitivity to ... Mar 29, 2006
DG News ...to overcome this chemical resistance within tumor cells, thereby allowing standard anti-cancer drugs such as cisplatin, carboplatin and paclitaxel to continue ...

Angiotech Pharma Says Data Indicate Numerical Trend Favoring TAXUS ... Mar 29, 2006
Trading Markets, ...said Wednesday that results from studies showed a positive numerical trend in the performance of Boston Scientific's TAXUS Express2 paclitaxel-eluting stent ...

Medtronic Sues Guidant in Ireland Mar 29, 2006
ag-IP-news Agency, Medtronic filed suit in the US District Court for the Eastern District of Texas against Boston Scientific, alleging that the TAXUS Paclitaxel-eluting coronary ...

New Drugs Added to Breast Cancer Guidelines: Presented at NCCN Mar 13, 2006
DG News ...by the National Comprehensive Cancer Network include numerous changes, including the addition of two new drugs -- bevacizumab and albumin-bound paclitaxel. ...

OXiGENE Completes Patient Enrollment in a Phase II Clinical Trial ... Mar 23, 2006
Business Wire (press release), ...triple combination of Combretastatin A4P (CA4P)--OXiGENE's lead therapeutic candidate--together with widely-used chemotherapy agents, carboplatin and paclitaxel ...

Stent Registry Safety Data Favors Taxus® Over Cypher® In The ... Mar 18, 2006
Medical News Today (press release), ...study included follow-up on 5,566 patients at eight coronary centers in the United States who received either a TAXUS® Express2â„¢ paclitaxel-eluting coronary ...

Sonus Pharmaceuticals to Present at Cowen & Co. 26th Annual Health ... Mar 2, 2006
PharmaLive.com (press release), The Company's lead oncology product candidate is TOCOSOL(R) Paclitaxel, a new formulation of the widely prescribed anti-cancer drug paclitaxel. ...

Researchers find environmentally friendly ways to produce more ... Mar 29, 2006
Checkbiotech.org (press release), ...potent versions of Taxol.". Taxol - generically known as paclitaxel - is a top-selling cancer-fighting drug. It's most commonly used ...

Diatos Announces Expansion of Medarex Cancer Product Licensing ... Mar 28, 2006
PR Newswire (press release), The company's therapeutic candidates DTS-301, a novel paclitaxel formulation and DTS-201, a doxorubicin prodrug, respectively entered Phase II and Phase I ...

Sonus to begin testing its second cancer drug Mar 17, 2006
The Herald, Tocosol paclitaxel, a chemotherapy drug, is being tested on about 800 breast cancer patients around the globe in a trial that should be finished this year. ...

Study Finds Shifts In Treatment Trends Prior To Publication Of ... Mar 17, 2006
Medical News Today (press release), Results from the Cancer and Leukemia Group B (CALGB) Study 9344 suggested that adjuvant treatment with the taxane drug paclitaxel is associated with improved ...

Comparison of Drug-Releasing Coronary Stents Show Similar ... Mar 2, 2006
DG News CHICAGO, IL -- March 2, 2006 -- Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary ...

Taxus Stents Superior to Brachytherapy in the Treatment if in ... Mar 15, 2006
DG News ...the American Medical Association (JAMA) on the Taxus V ISR (in-stent restenosis) clinical trial that found the Taxus(R) Express2(TM) paclitaxel-eluting stent ...

Angiotech And Boson Say JAMA Article States TAXUS Stents Superior ... Mar 15, 2006
Trading Markets, ...the Journal of the American Medical Association on the TAXUS V ISR clinical trial that demonstrated the efficacy of the TAXUS Express2 paclitaxel-eluting stent ...

JAMA article says TAXUS(R) stents superior to brachytherapy in the ... Mar 15, 2006
Yahoo! News (press release) ...of the American Medical Association (JAMA) on the TAXUS V ISR (in-stent restenosis) clinical trial that found the TAXUS® Express2(TM) paclitaxel-eluting stent ...

Brachytherapy for In-Stent Restenosis A Distant Second Choice to ... Mar 12, 2006
Journal of American Medical Association (subscription), In this issue of JAMA, Stone et al 17 and Holmes et al 18 report randomized comparisons of vascular brachytherapy vs a paclitaxel-eluting stent and a sirolimus ...

Drug-eluting stents best treatment for managing coronary ... Mar 13, 2006
News-Medical.net, About half of the patients received paclitaxel-eluting stents, while the other half received vascular brachytherapy, which delivers radiation to the inside of ...

Drug that opens a new front in the battle against breast cancer Mar 22, 2006
Times Online, The chemotherapy treatment, paclitaxel, attacks the tumour while Avastin interferes with the formation of blood vessels that starve it of nutrients. ...

STENT registry safety data favors TAXUS(R) over Cypher(R) in the ... Mar 12, 2006
MoneySense.ca (press release), ...included follow-up on 5,566 patients at eight coronary centers in the United States who received either a TAXUS(R) Express2(TM) paclitaxel-eluting coronary ...

Neoadjuvant Aromatase Inhibitors May Be as Effective as ... Mar 27, 2006
DG News In the chemotherapy group, 118 patients received 60 mg/m 2 of doxorubicin and 200 mg/m 2 of paclitaxel every 3 weeks for 4 cycles. ...

Abraxis Oncology Names Joseph Hogan Vice President of US Sales and ... Mar 20, 2006
Finanzen.net, Hogan will be responsible forleading the US sales and marketing teams for ABRAXANE(R) forInjectable Suspension (paclitaxel protein-bound particles ...

NYCOMED ASA Mar 27, 2006
Norway.org, ...of Health. Paclitaxel: A chemo-therapeutic agent, this is effective against certain types of breast and ovarian cancers. TachoComb ...

Boston Scientific to Release Broad Range of Clinical Study Results ... Mar 7, 2006
Finanzen.net, ..."The data we will present at ACC from our TAXUS clinical studies demonstrates the performance of the TAXUS Express2 paclitaxel-eluting stent system as an ...

International Approvals: Ionsys, CoStar, AutoXpress Mar 7, 2006
Medscape (subscription) ...approved a fentanyl HCl iontophoretic transdermal system for the management of acute postoperative pain in hospitalized adults, and a paclitaxel-eluting cobalt ...

Updated Guidelines for Treatment of Ovarian Cancer Mar 27, 2006
Cancer Consultants (press release), ...the following chemotherapy regimens were added as treatment options: Gemzar® (gemcitabine)/Paraplatin® (carboplatin) and Paraplatin/Taxol® (paclitaxel). ...

Merck stands aside as Bayer scoops up Schering Mar 27, 2006
Pharma Times (subscription), Schering has an improved formulation of the widely-used cancer drug paclitaxel in late-stage clinical testing, as well as oral VEGF inhibitor PTK/ZK, also in ...

Abraxis Oncology Names Joseph Hogan Vice President of US Sales and ... Mar 20, 2006
Business Wire (press release), Hogan will be responsible for leading the US sales and marketing teams for ABRAXANE(R) for Injectable Suspension (paclitaxel protein-bound particles for ...

Study puts drug-eluting stents to test in heart attack patients Mar 13, 2006
EurekAlert (press release), The Randomized Comparison of Paclitaxel Eluting Stent Versus Conventional Stent in ST-segment Elevation Myocardial Infarction (PASSION) study has taken the ...

Excellent in-stent restenosis clinical trial results reported for ... Mar 12, 2006
Canada NewsWire (press release), ...restenosis) clinical trial(1). The results demonstrated that patients treated for in-stent restenosis with the TAXUS(R) Express2(TM) paclitaxel-eluting stent ...

Angiotech partner to release broad range of clinical study results ... Mar 7, 2006
PR Newswire (press release), BSC will release nine-month results from the TAXUS V In-Stent Restenosis (ISR) clinical trial, which evaluates the TAXUS Express2 paclitaxel-eluting coronary ...

Cell Therapeutics, Inc. CEO Talks About Lung Cancer Treatments for ... Mar 9, 2006
PharmaLive.com (press release), XYOTAX (paclitaxel poliglumex) is a biologically-enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable ...

Concurrent Radiation Therapy and Chemotherapy for Small Cell Lung ... Mar 16, 2006
Cancer Consultants (press release), ...to an article recently published in the British Journal of Cancer, chemotherapy including Paraplatin® (carboplatin), Taxol® (paclitaxel), and Vepesid ...

Medtronic Sues Guidant In Ireland For Stent Patent Infringement ... Mar 28, 2006
Trading Markets, Medtronic alleged that the TAXUS® Paclitaxel-eluting coronary stent system infringes Medtronic's Fitzmaurice and Anderson patents. ...

JAMA Article Says TAXUS Stents Superior To Brachytherapy In ... Mar 15, 2006
Trading Markets, In the TAXUS Vs ISR (in-stent restenosis) clinical trial, it was found that TAXUS Express2 paclitaxel-eluting stent system was superior to radiation-based ...

Studies compare stents and cardiac procedures for long-term ... Mar 14, 2006
EurekAlert (press release), Richmond, used the pooled results of 15 independent head-to-head trials to compare the efficacy of sirolimus-eluting stents (SES) to paclitaxel-eluting stents ...

Examining stenting options in diabetics Mar 13, 2006
RxPG NEWS, Dr. Simonton and the STENT Group of eight coronary intervention centers have examined how the sirolimus-eluting (SES) and paclitaxel-eluting stents (PES ...

Boston Scientific files FDA application for new stent Mar 8, 2006
Reuters The medical device maker said it completed its premarket application for its Taxus Liberte paclitaxel-eluting coronary stent. The ...

Earnings: Microvision narrows loss in 4th quarter Mar 16, 2006
Seattle Post Intelligencer 81 cents per share, in 2004. Sonus said it is positioning its Tocosol Paclitaxel anti-cancer drug for approval and introduction.

Drug-Coated Stents Beat Radiation at Reopening Arteries Mar 12, 2006
Forbes ...companies that market coated stents -- Johnson & Johnson, whose stents are coated with sirolimus; and Boston Scientific, whose stents are coated with paclitaxel ...

UPDATE 1-Boston Scientific files FDA application for new stent Mar 8, 2006
Reuters The Natick, Massachusetts-based medical device maker said it completed a premarket application for its Taxus Liberte paclitaxel-eluting coronary stent. ...

Drug-coated stents work where older stents failed Mar 13, 2006
Reuters.uk, Two clinical studies indicate that inserting a stent covered with the drug paclitaxel or sirolimus inside the old clogged stent reduces the risk of the vessel ...

Boston Scientific Reports Excellent In-Stent Restenosis Clinical ... Mar 12, 2006
Trading Markets, ...from its TAXUS V ISR (in-stent restenosis) clinical trial showed that patients treated for in-stent restenosis with the TAXUS Express2 paclitaxel-eluting stent ...

Boston Scientific Submits PMA Application Final Module To FDA For ... Mar 8, 2006
Trading Markets, ...has submitted the final module of the Pre-Market Approval application to the US Food and Drug Administration for its TAXUS Liberte paclitaxel-eluting coronary ...

OXiGENE Completes Patient Enrollment In Clinical Trial Evaluating ... Mar 23, 2006
Trading Markets, ...of the triple combination of Combretastatin A4P (CA4P | charts | news | Powerrating) together with widely-used chemotherapy agents, carboplatin and paclitaxel. ...

Abdominal Chemo Boosts Survival In Ovarian Cancer Patients Mar 10, 2006
eMaxHealth.com, The benefits were overshadowed by the promise of new chemotherapy drugs such as paclitaxel, one of the chemo drugs used in Armstrong's study. ...

Pro-Pharmaceuticals' Abstract Accepted for Publication in ASCO ... Mar 17, 2006
International News Service, The Company has been conducting clinical and pre-clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ...

Antisoma's Completes Enrollment in Ovarian Cancer Trial Mar 20, 2006
International News Service, The standard chemotherapy regime for these ovarian cancer patients is carboplatin and paclitaxel, the same as in the ongoing lung cancer study. ...

Drug-Releasing Stents More Effective Than Radiation Mar 13, 2006
Ivanhoe, The first study finds stents that release the drug paclitaxel to treat the narrowing within an implanted bare-metal stent prevent the risk of re-narrowing ...

US Advisers Against New Indication for Gemzar Mar 15, 2006
Cancerpage.com, Reuters) - Advisers to the US Food and Drug Administration recommended on Monday against approving Eli Lilly & Co.'s Gemzar (gemcitabine/paclitaxel) to treat ...

Es gibt keinen Besseren Mar 15, 2006
Finanzen.net, ...the safety and efficacy of the XIENCE V Everolimus ElutingCoronary Stent System compared to the TAXUS(R) Express 2(TM)Paclitaxel-Eluting Coronary Stent System ...

Drug-eluting stent beat radiation in study Mar 13, 2006
United Press International The nine-month study showed that patients treated with the Taxus stents -- which are coated with the drug paclitaxel -- reduced the need for additional artery ...

Stent Repair: Coated replacements better than radiation Mar 17, 2006
Science News Only 9 percent and 11 percent of stents laced with the drugs sirolimus (Rapamycin) and paclitaxel (Taxol), respectively, needed to be reopened during the two 9 ...

Oncologists Jumped Gun on Taxanes After Oral Presentation Mar 17, 2006
MedPage Today, The CALGB 9344 results reported in 1988 showed that adjuvant Taxol (paclitaxel) significantly improved survival for women with lymph-node-positive breast cancer ...

Phase III Non-Small Cell Lung Cancer Trial Studying Nexavar ... Feb 26, 2006
Medical News Today (press release), III clinical trial studying Nexavar® (sorafenib) tablets administered in combination with the chemotherapeutic agents carboplatin and paclitaxel in patients ...

Meeting Presentations Can Influence Treatment Patterns Mar 15, 2006
Medscape (subscription) ...with breast cancer who were diagnosed soon after a scientific presentation and widespread media coverage of the results from a trial of paclitaxel for early ...

Guidant Completes Enrollment in Randomized US Portion of Drug ... Mar 15, 2006
Business Wire (press release), ...evaluating the safety and efficacy of the XIENCE V Everolimus Eluting Coronary Stent System compared to the TAXUS(R) Express 2(TM) Paclitaxel-Eluting Coronary ...

Concurrent Radiation Therapy and Chemotherapy for Small Cell Lung ... Mar 16, 2006
Cancer Consultants (press release), ...with limited small cell lung cancer (SCLC) following concurrent radiotherapy and chemotherapy with Paraplatin® (carboplatin), Taxol® (paclitaxel) and Vepesid ...

Taxotere®/Platinol®/Herceptin® Effective in Locally Advanced ... Mar 22, 2006
Cancer Consultants (press release), Herceptin is currently approved for the treatment of HER2-positive, metastatic breast cancer with the chemotherapy agent Taxol® (paclitaxel), or as a single ...

Angiotech partner submits final module for TAXUS(R) Liberte(TM) ... Mar 8, 2006
Yahoo! News (press release) US Food and Drug Administration (FDA) the final module of BSC's Pre-Market Approval (PMA) application for its TAXUS® Liberte(TM) paclitaxel-eluting coronary ...

SD Pharma wraps up pre-clinical studies Mar 24, 2006
San Diego Daily Transcript (subscription), ...(News) in Carlsbad announced Friday that it has completed a battery of pre-clinical studies on its novel nano-emulsion formulation of paclitaxel, a formulation ...

Taxol® and Paraplatin® Superior to Novantrone® for Hormone ... Mar 10, 2006
Cancer Consultants (press release), According to an article recently published in the journal Urology, treatment consisting of Taxol® (paclitaxel) and Paraplatin® (carboplatin) provides ...

Conor Medsystems Licenses Compound from Novartis for Development ... Mar 16, 2006
PharmaLive.com (press release), One stent will be loaded with pimecrolimus, and the other stent will be a dual-drug stent loaded with both pimecrolimus and paclitaxel. ...

At the Crossroads of Medicine and Money Feb 26, 2006
Los Angeles Times, It wraps one of the best-known cancer fighters — paclitaxel, a compound derived from the Pacific yew — inside particles of a blood protein thousands of ...

Angiotech shares up on Taxus registry data Mar 14, 2006
BusinessWeek Boston Scientific, based in Natick, Mass., bought worldwide exclusive rights from Vancouver, British Columbia-based Angiotech to use paclitaxel to coat its ...

Angiotech Shares Up on Taxus Registry Data Mar 14, 2006
Houston Chronicle, Boston Scientific, based in Natick, Mass., bought worldwide exclusive rights from Angiotech to use paclitaxel to coat its coronary stent products and has co ...

Early, Unproven Findings Changing Doctors' Practice Mar 14, 2006
Forbes In the JNCI study, Giordano's group tracked changes in breast-cancer treatment after researchers announced preliminary findings on Taxol (paclitaxel) at the ...

Taxus holds market share Mar 14, 2006
Pioneer Press, ...force, Kucheman said. Barracuda stents will be coated initially with the same drug as the Taxus, paclitaxel. Eventually, the product ...

STENT Registry Safety Data Favors TAXUS Over Cypher In The Most ... Mar 12, 2006
Trading Markets, The study included follow-up on 5,566 patients at eight coronary centers in the United States who received either a TAXUS Express2 paclitaxel-eluting coronary ...

ACC: Taxus Stent Beats Radiation for Treating InStent Restenosis Mar 12, 2006
MedPage Today, ATLANTA, March 12 - Putting the Taxus Taxol (paclitaxel)-eluting stent within a failed bare-metal stent beats vascular brachytherapy at preventing restenosis ...

Boston Scientific Submits Final Module Of Its Pre-Market Approval ... Mar 8, 2006
Trading Markets, ...it has submitted the final module of its Pre-Market Approval (PMA | charts | news | Powerrating) application for its TAXUS Liberte paclitaxel-eluting coronary ...

Dose-Dense Chemotherapy Safe and Effective; Particularly for ... 21 Dec 2005
Cancer Consultants (press release), Patients received the study drugs Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide), either concurrently, or sequentially in ...

Integrated BioPharma Announces the Appointment of General Hill as ... 21 Dec 2005
PR Newswire (press release), Its pharmaceutical business operates a cGMP facility for the production and sale of Paclitaxel and related drugs and provides technical services through its ...

American Bioscience Inc. Names Barry Flannelly, Pharm.D, MBA, as ... 21 Dec 2005
PR Newswire (press release), ...entirely to developing and promoting innovative, next-generation cancer therapies such as ABRAXANE(R) for Injectable Suspension (paclitaxel protein-bound ...

GPC Biotech Submits CMC Section Of Satraplatin NDA 21 Dec 2005
BioWorld Online (subscription), ...satraplatin include a Phase II monotherapy trial among metastatic breast cancer patients, a Phase II combination trial with Taxol (paclitaxel) for inoperable ...

Herceptin, new breast cancer medication 21 Dec 2005
Auburn Citizen, The FDA has approved Herceptin as a first line use with paclitaxel, a class of chemotherapy drugs that prevent cancer cell division and promote cancer cell ...

Little Difference between Docetaxel and Paclitaxel in Treating ... Dec 14, 2005
DG News ...is virtually no difference in disease-free survival when a regimen comprising doxorubicin and cyclophosphamide is followed by either docetaxel or paclitaxel. ...

Paclitaxel, docetaxel show similar breast cancer benefit Dec 9, 2005
myDNA.com, Results from a clinical trial comparing the effectiveness of the drugs paclitaxel and docetaxel, delivered over two different dosing schedules, showed that ...

Bioxel Wins Paclitaxel Purchase Agreement With A New European ... Dec 9, 2005
CCNMatthews (Communiqués de presse), Bioxel's client is already marketing its generic paclitaxel formulation in several EU countries and intends to obtain approvals throughout Europe in 2006. ...

Sonus Pharmaceuticals to Present TOCOSOL(R) Paclitaxel Clinical ... Dec 2, 2005
Business Wire (press release), 2, 2005--Sonus Pharmaceuticals, Inc. (NASDAQ:SNUS) today announced the scheduled presentation of a poster on TOCOSOL(R) Paclitaxel at the upcoming San Antonio ...

Some stents may cause allergic reactions Dec 19, 2005
Science Daily (press release) Study: Paclitaxel stents more effective (September 13, 2005) -- Researchers say stents that release the medication paclitaxel reduce the risk of an artery re ...

Sonus Pharmaceuticals Presents Encouraging Phase 2 Efficacy and ... Dec 8, 2005
PharmaLive.com (press release), ...(Nasdaq: SNUS) today presented encouraging safety and efficacy data from the Phase 2 clinical program for TOCOSOL(R) Paclitaxel at the San Antonio Breast ...

Sonus Pharmaceuticals to Present TOCOSOL Paclitaxel Clinical Data ... Dec 2, 2005
PharmaLive.com (press release), ...(NASDAQ:SNUS) today announced the scheduled presentation of a poster on TOCOSOL(R) Paclitaxel at the upcoming San Antonio Breast Cancer Symposium, to be held ...

Pilot Study Shows Abraxane Safe and Effective in Sequence with ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- A novel form of paclitaxel, encapsulated in albumin, could represent the first drug designed to treat breast cancer ...

Two Types of Breast Cancer Treatments Show Similar Benefit Dec 9, 2005
PharmaLive.com (press release), WASHINGTON, December 8, 2005-Results from a clinical trial comparing the effectiveness of the drugs paclitaxel and docetaxel, delivered over two different ...

*vwd/BUSINESS WIRE: SMT steigt in die erste Liga der Hersteller ... Dec 15, 2005
Vereinigte Wirtschaftsdienste, SMT hat für einen ihrer führenden mit Medikamenten beschichteten Stents, das "Infinnium(TM) Paclitaxel System", die Zulassung vom Medicine Evaluation Board ...

SMT joins Big League of Drug Eluting Stent Manufacturers Dec 15, 2005
Business Wire (press release), ...the European Community's Medicine Evaluation Board (MEB) in the Netherlands -- for one of their lead drug eluting stents, the "Infinnium(TM) Paclitaxel System ...

Symptoms and signs of an acute myocardial ischemia caused by ... Dec 16, 2005
HeartZine, Introduction: Paclitaxel (Taxol) is an anticancer agent used for the treatment of breast and ovarian cancer. The major side effects ...

Xechem Settles Antitrust Lawsuit Against Bristol-Meyers Squibb for ... Dec 20, 2005
Genetic Engineering News, ...that Bristol-Meyers had engaged in anticompetitive practices relating to Xechem's efforts to manufacture and bring to market the drug paclitaxel, a generic ...

Pivotal Trial to Evaluate Comparative Effectiveness of XYOTAX to ... Dec 6, 2005
PharmaLive.com (press release), ...(CTI) today announced plans to initiate a clinical trial in women of XYOTAX (paclitaxel poliglumex) versus paclitaxel chemotherapy for the treatment of PS2 ...

Pivotal Trial to Evaluate Comparative Effectiveness of XYOTAX(TM) ... Dec 6, 2005
PR Newswire (press release), ...(CTI) (Nasdaq and MTAX: CTIC) today announced plans to initiate a clinical trial in women of XYOTAX (paclitaxel poliglumex) versus paclitaxel chemotherapy for ...

Bioxel Pharma Announces Results for the Third Quarter of 2005 Nov 23, 2005
CCNMatthews (Communiqués de presse), European generic market, we have significantly reduced our production costs and we have broadened our taxanes product line to paclitaxel and docetaxel ...

Mayo Clinic Reports Tamoxifen Benefit For Breast-cancer Patients ... Dec 19, 2005
Science Daily (press release) ...metastatic breast cancer. The researchers tested a combination of two drugs -- paclitaxel and ... > full story. Raloxifene After ...

Mayo Clinic Discovers Two Key Players In Cancer Prevention And How ... Dec 19, 2005
Science Daily (press release) ...metastatic breast cancer. The researchers tested a combination of two drugs -- paclitaxel and ... > full story. Mayo Clinic Cancer ...

C-myc Gene Influences Response to Herceptin® Dec 14, 2005
Cancer Consultants (press release), The researchers evaluated patients in the NSABP B-31 clinical trial, which compared treatment with AC-T (doxorubicin,cyclophosphamide,paclitaxel) to treatment ...

Dose-Dense Chemotherapy Found More Effective than Standard ... Dec 13, 2005
DG News ...one arm of the study patients received doxorubicin 60 mg/m 2 every 2 weeks over a 22-week period, cyclophosphamide over a 14 week period, and paclitaxel (Taxol ...

(PRN) Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast ... Dec 9, 2005
Houston Chronicle, However, the toxicities associated with solvent-based paclitaxel formulations limited the chemotherapy dose that can be given," said Patrick Soon-Shiong, MD ...

Angiotech completes acquisition of Lifespan(R) vascular graft ... Dec 1, 2005
PR Newswire (press release), ...existing Lifespan product line for a period of up to five years, and will be the exclusive distributor of Angiotech's Vascular Wrap(TM) paclitaxel-eluting mesh ...

Breast Cancer Treatment Dec 16, 2005
Food Consumer, 153. Henderson IC, Berry DA, Demetri GD, et al.: Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant ...

Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast Cancer ... Dec 9, 2005
PR Newswire (press release), Setting in Breast Cancer * Data are Timely in Light of North American Breast Cancer Intergroup Adjuvant Trial Results Solidifying the Role of Paclitaxel in the ...

Curcumin halts spread of breast cancer in mice Dec 6, 2005
Xagena.it, ...the nontoxic natural substance not only repelled progression of the disease to the lungs, but also appeared to reverse the effects of Paclitaxel ( Taxol ), a ...

Combination chemotherapies slow small cell lung cancer and cancer ... Nov 30, 2005
PharmaLive.com (press release), The combination of paclitaxel/carboplatin/etoposide as a first line treatment produces significant improvement in stopping progression of extensive stage small ...

GPC Biotech Announces Start of Phase 2 Trial Evaluating ... Dec 9, 2005
Market Wire (press release) NASDAQ: GPCB) today announced that a Phase 2 study evaluating the Company's lead drug candidate, satraplatin, in combination with Taxol® (paclitaxel) as a ...

Kosan Reports KOS-862 Interim Phase II Results in Patients With ... Dec 8, 2005
Yahoo! News (press release) ...metastatic breast cancer. KOS-862 is a polyketide that inhibits cancer cells by the same mechanism as paclitaxel. Interim results ...

Updated Results from Phase III Trial Evaluating Addition of ... Dec 9, 2005
Cancer Consultants (press release), Group (ECOG) recently reported updated results from the E2100 Trial in which the addition of Avastin (bevacizumab) to Taxol® (paclitaxel) was evaluated in the ...

TAXUS(TM) Stent Demonstrates Excellent Efficacy and Safety in ... Nov 29, 2005
Finanzen.net, ...multicentre STENT registry that further demonstrate the efficacy and safety of Boston Scientific's TAXUS(TM) Express2(TM) paclitaxel-eluting coronary stent ...

Conor Medsystems Purchases Assets of Phytogen Life Sciences Nov 22, 2005
PR Newswire (press release), ...that it has purchased substantially all of the assets of Phytogen Life Sciences Inc., including its inventory of finished paclitaxel, for approximately $3.8 ...

Conor Medsystems Acquires Assets of Bankrupt Phytogen Life ... Nov 28, 2005
TechFinance, ...announced the acquisition of substantially all of the assets of Phytogen Life Sciences Inc., including its inventory of finished paclitaxel, for approximately ...

Rival bidder has roots in Indiana Dec 6, 2005
Indianapolis Star, Three years ago, Boston Scientific used its legal muscle to stop Guidant from getting access to the paclitaxel drug coating on heart stents. ...

Kosan said cancer study encouraging Dec 8, 2005
BusinessWeek Kosan said KOS-862 works similarly to the paclitaxel chemotherapy, but preclinical studies have shown it effective against paclitaxel-resistant tumors. ...

The power of one Dec 11, 2005
Indianapolis Star, ...design. • Drug-coated stent for artery in the thigh (drug prevents scar tissue growth) -- 2006 or 2007; uses paclitaxel coating. ...

Human Genome Sciences Reports Interim Results of Phase 1b Clinical ... Nov 17, 2005
PR Newswire (press release), A poster entitled "A Phase 1 and Pharmacological Study of HGS-ETR1, an Antibody Targeting TRAIL-R1, in Combination with Paclitaxel and Carboplatin in Patients ...

Dose-Dense Chemotherapy Safe and Effective—Particularly for ... Dec 13, 2005
Cancer Consultants (press release), Patients were first randomly assigned to receive concurrent Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide) or concurrent ...

Taxotere® Vs. Taxol® in Adjuvant Treatment of Breast Cancer Dec 14, 2005
Cancer Consultants (press release), Taxotere® (docetaxel) and Taxol® (paclitaxel) produce similar outcomes when given after Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide) in the ...

Bristol-Myers Squibb: $1 billion cost savings by 2008 Dec 14, 2005
Pharmaceutical Business Review ...because of a shift in its product mix - from selling a high proportion of blockbuster drugs, such as Glucophage (metformin) and Taxol (paclitaxel), to lower ...

cMyc Amplification Confers Increased Activity with the Addition of ... Dec 13, 2005
Cancer Consultants (press release), The researchers evaluated patients enrolled in the NSABP B-13 trial in which AC-T (doxorubicin, cyclophosphamide, paclitaxel) was compared with AC-TH ...

NCCN Announces Two New Breast Cancer Resources Dec 6, 2005
Business Wire (press release), For metastatic disease, new regimens including paclitaxel (Taxol) plus bevacizumab (Avastin) and albumin-bound paclitaxel (Abraxane) were added to the existing ...

Trastuzumab Used as First Line Therapy in Women Whose Cancer Has ... Dec 12, 2005
DG News ...the same time to progression and overall survival as what has been seen in other studies using trastuzumab in combination with either docetaxel or paclitaxel. ...

Spectrum Pharmaceuticals Announces Start of Phase 2 Trial ... Dec 9, 2005
Yahoo! News (press release) ...announced the opening of accrual of a Phase 2 study evaluating the Company's lead drug candidate, satraplatin, in combination with Taxol® (paclitaxel) as a ...

Guidant Enrolls First Patient in Japan Arm of Drug Eluting Stent ... Dec 13, 2005
Finanzen.net, ...randomized portion in the United Statesis a prospective, single-blind trial comparing XIENCE V versus theTAXUS(R) Express 2(TM) paclitaxel eluting coronary ...

Taxotere® and Taxol® Produce Same Results Following AC in ... Dec 15, 2005
Cancer Consultants (press release), G (CALGB) and the North Central Cancer Treatment Group (NCCTG) recently reported results that both Taxotere (docetaxel) and Taxol (paclitaxel) following AC ...

SABCS: Shorter Chemotherapy Regimen Plus Taxol Reduces Breast ... Dec 12, 2005
MedPage Today, SAN ANTONIO, Dec 12 - A shorter standard adjuvant chemotherapy regimen, augmented by weekly doses of Taxol (paclitaxel), led to a 37% reduction in the relative ...

Taxol reduces breast cancer recurrence Dec 15, 2005
myDNA.com, New research finds that the cancer drug Taxol (paclitaxel), in conjunction with more concise chemotherapy periods, offers an increased chance of breast cancer ...

Professor Peter van Brummelen and Dr. Annick Schwebig Join the ... Dec 14, 2005
PR Newswire UK (press release), The company's therapeutic candidates DTS-301, a novel paclitaxel formulation and DTS-201, a doxorubicin prodrug, respectively entered Phase II and Phase I ...

SD Pharmaceuticals Completes Studies on the Feasibility of a Novel ... Dec 14, 2005
Genetic Engineering News, ...shock, vein irritation and phlebitis associated with the currently marketed formulations; these include Vinorelbine, Paclitaxel, Clarithromycin and Vancomycin. ...

Hana Biosciences Announces Changes to Strengthen Management Team Dec 16, 2005
Business Wire (press release), ...marketing at Bristol-Myers Squibb, responsible for pipeline development, licensing and life cycle management for cancer products including Taxol (paclitaxel). ...

Rolling NDA Submission Begun for Lead Drug Satraplatin in Hormone ... Dec 15, 2005
PharmaLive.com (press release), Phase 3 registrational trial, announced the opening of accrual of a Phase 2 study evaluating satraplatin in combination with Taxol(R) (paclitaxel) and reported ...

Sonus drug effective in patient tests Dec 9, 2005
Bothell Herald, ...breast cancer. The test data on Tocosol paclitaxel were presented Thursday at the San Antonio Breast Cancer Symposium in Texas. Among ...

Bioxel Pharma Secures Financing for Anticancer Drug Development ... Dec 16, 2005
CCNMatthews (Communiqués de presse), The Corporation sells cGMP paclitaxel and develops a portfolio of other generic taxane APIs and taxane-based proprietary products for improved cancer therapy. ...

UPDATE 1-Eli Lilly says Canada OKs Gemzar combination Nov 28, 2005
Reuters 28 (Reuters) - Eli Lilly Canada said on Monday Canadian health regulators had approved its chemotheraphy drug, Gemzar, in combination with paclitaxel, to treat ...

New Clinical Study of Phenoxodiol as Chemo-sensitizer for ... Nov 28, 2005
Yahoo! News (press release) ...is commonly used in patients with recurrent or persistent ovarian cancer that have failed other therapies, including the first-generation taxane, paclitaxel. ...

Conor Medsystems buys Phytogen assets, ends royalties Nov 22, 2005
San Francisco Business Times, The deal lets Conor (NASDAQ:CONR) stop paying royalties to Phytogen for sales of a Conor stent that used paclitaxel, a Phytogen drug made from the Chinese yew ...

Spectrum Pharmaceuticals Presents Data at the AACR-NCI-EORTC ... Nov 18, 2005
PR Newswire (press release), ...peer-reviewed journal, Breast Cancer Research and Treatment * SPI-1620 transiently increases blood flow to tumors * Selectively enhances paclitaxel delivery to ...

Spectrum Pharmaceuticals Presents Data at the AACR-NCI-EORTC ... Nov 18, 2005
PR Newswire (press release), Data published in the abstract clearly shows that SPI-1620 significantly enhances the efficacy of paclitaxel. Animals treated with ...

Kereos Appoints Allen Nickols, Ph.D., as Vice President of Biology Dec 13, 2005
Biotech Intelligence (press release), ..."His addition enables us to more effectively advance our integrin-targeted MRI and paclitaxel agents and, perhaps most importantly, successfully position them ...

Major Ovarian Cancer Clinical Study Announced At Yale Using ... Nov 28, 2005
Science Daily (press release) ...commonly used in patients with recurrent or persistent ovarian cancer that has failed other therapies, including the first generation taxane paclitaxel. ...

Bioxel Pharma Broadens its Taxane Product Line Nov 18, 2005
CCNMatthews (press release), ...ingredients (APIs) and developer of targeted oncology drugs, today announced the filing of a new patent covering the manufacturing of paclitaxel and docetaxel ...

PRESS RELEASE:Boston Scientific Sues Singapore Biosensors Dec 13, 2005
Yahoo! News The European Patent encompasses, among other things, claims describing a stent that uses a composition of Paclitaxel and a polymeric coating as a drug carrier. ...

(PRN) US Oncology Research Network Presenting Numerous Studies at ... Dec 11, 2005
Houston Chronicle, Results of a Phase II Trial of Combination Therapy with Oral Capecitabine and Weekly Paclitaxel for Metastatic Breast Cancer: Preliminary Results in Taxane Pre ...

Chemo after surgery extends life in endometrial cancer Dec 9, 2005
Reuters.uk, They are currently conducting a study to see if two other chemotherapy drugs -- carboplatin and paclitaxel -- will be as effective, but with fewer side effects ...

Hot Stocks: KR SNDK EVCI BA LMT NOC DV SSD DDS TP FRSH -2 Dec 6, 2005
Yahoo! News CELL THERAPEUTICS INC (CTIC) Said it plans to initiate a clinical trial in women of Xyotax versus paclitaxel chemotherapy for the treatment of poor performance ...

American Pharmaceutical Partners to Merge with Parent Company ... Nov 28, 2005
PR Newswire (press release), ...disease. Coroxane(TM), nab(TM) paclitaxel, is in mid-stage clinical trials for both coronary and peripheral artery restenosis. Applications ...

SABCS: Herceptin-Anthracycline Cardiotoxicity Called Real and ... Dec 8, 2005
MedPage Today, Norman Wolmark, MD, professor of oncology at Drexel College of Medicine in Philadelphia, said earlier studies, using Taxol (paclitaxel), had shown a similar ...

Highlights of rising and falling US stocks Dec 6, 2005
Investor's Business Daily (subscription) Cell Therapeutics (CTIC) said it plans to initiate a clinical trial of the use of its Xyotax paclitaxel chemotherapy for the treatment of poor performance ...

Chemotherapy after surgery extends survival for patients with ... Dec 5, 2005
EurekAlert (press release), Another GOG study is underway to see if the chemotherapy drugs carboplatin and paclitaxel will be as effective, but with fewer serious side effects. ...

Ritalin Conjugate Used to Treat "Chemo-Brain" in Breast Cancer ... Dec 13, 2005
DG News The most commonly used regimens were cyclophosphamide, doxorubicin, paclitaxel, 5-fluorouracil, methotrexate, docetaxel and carboplatin. ...

Pro-Pharmaceuticals Announces Two International Clinical Sites in ... Dec 13, 2005
Genetic Engineering News, The Company has been conducting pre-clinical and clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ...

Chemo After Surgery Extends Life in Advanced Endometrial Cancer Dec 9, 2005
Cancerpage.com, The research group is currently conducting a study to see if carboplatin and paclitaxel will be as effective, but with fewer side effects, in women with ...

SABCS: No Differences Found In Taxane Treatment Results Dec 9, 2005
MedPage Today, Details of the 4,988-woman Eastern Cooperative Oncology Group E1199 study comparing Taxotere (docetaxel) and Taxol (paclitaxel) were released early at the San ...

New Study of VEGF Signalling Inhibitor AZD2171 Used in the First ... Nov 23, 2005
PR Newswire UK (press release), ...overall survival and tumour response rate in patients with advanced NSCLC by comparing the efficacy of 'doublet' chemotherapy (paclitaxel and carboplatin) plus ...

Addition of Taxol® to Chemotherapy Combination Improves Survival ... Nov 29, 2005
Cancer Consultants (press release), According to a recent article published in the Journal of Clinical Oncology, the addition of the chemotherapy agent Taxol® (paclitaxel) to Platinol ...

CuraGen and TopoTarget Announce Presentation of PXD101 Phase I ... Dec 12, 2005
PharmaLive.com (press release), ...for solid tumors, including colorectal cancer, and a Phase Ib trial exploring the safety and potential activity of PXD101 in combination with paclitaxel and/or ...

OXiGENE Receives Regulatory Clearance to Commence Phase III ... Dec 12, 2005
Genetic Engineering News, ...the use of CA4P in both single-agent and combination therapies, including a Phase II trial evaluating CA4P in combination with carboplatin/paclitaxel for the ...

SABCS: Dose-Dense Chemotherapy Called Safe and Effective Dec 12, 2005
MedPage Today, ...to be answered. The study drugs were Adriamycin (doxorubicin), Taxol (paclitaxel), and Cytoxan (cyclophosphamide). In the sequential ...

Other News To Note Dec 9, 2005
TMCnet GPC Biotech AG, of Martinsried, Germany, said a Phase II study evaluating its lead drug candidate, satraplatin, in combination with Taxol (paclitaxel) as a ...

Oceans of medical potential Dec 9, 2005
Baltimore Sun, ...on compounds found in plants, soils and other terrestrial sources have been approved by the Food and Drug Administration, including paclitaxel, approved in ...

OXiGENE Receives Regulatory Clearance to Commence Phase III ... Dec 12, 2005
Finanzen.net, ...the use of CA4P in both single-agent and combinationtherapies, including a Phase II trial evaluating CA4P in combinationwith carboplatin/paclitaxel for the ...

Induction Chemotherapy and Concomitant Chemoradiotherapy Promising ... Dec 6, 2005
Cancer Consultants (press release), ...treated with induction Gemzar® (gemcitabine) and Platinol® (cisplatin) followed by concurrent radiation and chemotherapy with Gemzar and Taxol® (paclitaxel ...

CuraGen and TopoTarget Announce Updated PXD101 Phase I Results ... Nov 18, 2005
Yahoo! News (press release) Furthermore, PXD101 exhibited additive to synergistic activity when combined with other chemotherapeutic agents, including carboplatin and paclitaxel. ...

ABI In $4B Merger With APP To Create Abraxis BioScience Nov 28, 2005
BioWorld Online (subscription), Developed using ABI's NAB technology, Abraxane combines paclitaxel with albumin and is formulated into a nanoparticle, an administration that allows for higher ...

Conor Medsystems Receives FDA Approval for Full Expansion of ... Dec 1, 2005
PharmaLive.com (press release), Antiproliferative for Restenosis) is a randomized, single-blind, non-inferiority study comparing Conor's CoStar(TM) cobalt chromium paclitaxel-eluting stent ...

Conor to expand CoStar/Taxus stent study Dec 1, 2005
United Press International Conor said it is testing its CoStar stent in a randomized, single-blind, non-inferiority study comparing the cobalt chromium paclitaxel-eluting stent with ...

Indian stent gets European certification Dec 2, 2005
Webindia123, ..."The CE mark for our indigenously developed infinnium paclitaxel eluting coronary stent will help make stent therapy affordable for millions of patients ...

Human Genome Sciences Reports Results of Phase 1 Clinical Trials ... Nov 17, 2005
PR Newswire (press release), ...results demonstrated that the in vitro cytotoxicity of HGS-ETR2 was amplified through the addition of chemotherapeutic agents including paclitaxel and docetaxel ...

AstraZeneca starts lung cancer drug study Nov 23, 2005
Life Style Extra, ...and tumour response rate in patients with advanced non-small-cell lung cancer by comparing the efficacy of 'doublet' chemotherapy, paclitaxel and carboplatin ...

FDA gives permission for expansion of Conor stent trial Dec 2, 2005
Pharmaceutical Business Review The trial compares Conor's CoStar cobalt chromium paclitaxel-eluting stent with Boston Scientific's Taxus Express2 drug-eluting stent in the treatment of new ...

Angiotech Pharmaceuticals "hold," target price raised Nov 25, 2005
New Ratings ...published yesterday, the analysts mention that the company has reported positive results for the trial evaluating the safety of the paclitaxel-loaded vascular ...

New Study Published in PNAS Confirms Potential Utility of ... Nov 28, 2005
Market Wire (press release) Marillion is currently using its nanoparticles to carry the widely used chemotherapeutic drug paclitaxel into ovarian tumors, and it plans to initiate clinical ...


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