omeprazole

omeprazole information and resources from the National Cancer Institute

NCI Thesaurus | omeprazole

A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic properties and does not antagonize histamine H2 receptors. NCI Thesaurus | omeprazole

A benzimidazole with selective and irreversible proton pump inhibition activity. Omeprazole forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic properties and does not antagonize histamine H2 receptors.



news articles



Santarus Announces US Launch of ZEGERID Capsules; First and Only ... Mar 28, 2006
Business Wire (press release), ...focused on therapies for gastrointestinal (GI) diseases and disorders, today announced the US commercial launch of ZEGERID(R) (omeprazole/sodium bicarbonate ...

Santarus Receives FDA Approval for ZEGERID with Magnesium ... Mar 27, 2006
Genetic Engineering News, Food and Drug Administration (FDA) has approved the company's New Drug Application (NDA) for ZEGERID(R) with Magnesium Hydroxide (omeprazole/sodium bicarbonate ...

Premio beats Ark Animal Mar 27, 2006
The Mindanao Daily Mirror, Premio Omeprazole defeated The Ark Animal 95-83 while Bayer Crop Science bested Unified Sales Team 87-85 in the ongoing Everball Basketball Tournament held ...

Santarus Announces US Launch of ZEGERID Capsules Mar 31, 2006
EndoNurse, ...company focused on therapies for gastrointestinal (GI) diseases and disorders, announced the US commercial launch of ZEGERID® (omeprazole/sodium bicarbonate ...

Santarus Receives FDA Approval for Zegerid With Magnesium ... Mar 27, 2006
DG News Food and Drug Administration (FDA) has approved the company's New Drug Application (NDA) for Zegerid(R) with Magnesium Hydroxide (omeprazole/sodium bicarbonate ...

Axcan submits FDA amendment to its new drug application for ... Mar 29, 2006
CNW Telbec (Communiqués de presse), ...of duodenal ulcer compared Axcan's HELIZIDE regimen (3 capsules given 4 times a day) given in combination with two daily doses of 20 mg of omeprazole, to the ...

Santarus' ZEGERID Gets FDA Approval; Not To Market In 2006 ... Mar 27, 2006
Trading Markets, Contrary to this, ZEGERID utilizes one or more antacids instead of an enteric coating to protect the omeprazole from gastric acid degradation. ...

DGAP-News: STADA: Final financial figures for 2005 confirm robust ... Mar 29, 2006
Financial.de, The best-selling active ingredients in the Group were thereby the stomach medicine Omeprazole (EUR 70.0 million, +29%) and the cholesterol lowerer Simvastatin ...

Drug Web site receives revamp Mar 29, 2006
Cibola County Beacon, ...single molecule.â€?. Another example Thompson described was a generic drug called omeprazole, which was a 20-mg dosage tablet. It ...

Govt redraws list of prescription drugs Mar 29, 2006
Financial Express, Commonly known drugs like Cetrizine, Omeprazole, etc find a mention in the new Schedule H. The drugs newly added to the list include Tramadol, Cisplastin ...

Debate continues over interaction between ritonavir-boosted ... Mar 22, 2006
Aidsmap, These drugs include proton pump inhibitors such as omeprazole (Losec) and histamine-2 blockers like ranitidine (Zantac). The results ...

Gastric Ulcers Mar 20, 2006
TheHorse.com, ...complete waste.". The third drug that can be administered--the one which shuts down acid secretion--is omeprazole (Prilosec). "Because ...

Santarus Announces Positive Results with ZEGERID in Nocturnal Acid ... Mar 8, 2006
Business Wire (press release), ...diseases and disorders, today announced positive results from a recently completed clinical study that evaluated ZEGERID(R) (omeprazole/sodium bicarbonate ...

Positive Results with ZEGERID in Nocturnal Acid Breakthrough ... Mar 8, 2006
EndoNurse, ...diseases and disorders, announced positive results from a recently completed clinical study that evaluated ZEGERID® (omeprazole/sodium bicarbonate) Powder for ...

Santarus Launches ZEGERID Capsules In The US - Update Mar 28, 2006
Trading Markets, Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long term with omeprazole, Santarus said.

Gastroesophageal Reflux Disease (GERD) Effective Health Care ... Mar 27, 2006
Community Dispatch (press release) ...surgery. PP-Is include AcipHex®, Nexium®, Prevacid®, Protonix®, and Prilosec OTCâ„¢, as well as the generic drug omeprazole. ...

Santarus Receives FDA Approval for ZEGERID Capsules; First and ... Feb 27, 2006
International News Service, ...announced that the US Food and Drug Administration (FDA) has approved the company's New Drug Application (NDA) for ZEGERID(R) (omeprazole/sodium bicarbonate ...

Santarus Receives FDA Approval for Zegerid Capsules; First and ... Feb 28, 2006
DG News ...announced that the US Food and Drug Administration (FDA) has approved the company's New Drug Application (NDA) for Zegerid(R) (omeprazole/sodium bicarbonate ...

Santarus Gets Approval for Zegerid Capsules Mar 1, 2006
International News Service, Unlike delayed-release PPIs, Zegerid utilizes sodium bicarbonate in lieu of an enteric coating to protect the omeprazole from gastric acid degradation. ...

Santarus Joins the Compass Healthcare Communications Client Roster Mar 23, 2006
PharmaLive.com (press release), Compass will support Zegerid® (omeprazole/sodium bicarbonate), the first and only immediate release oral proton pump inhibitor, providing rapid release of the ...

Chocolate can be healthful — just don't live on it Mar 19, 2006
Seattle Times, Your diabetes medicine metformin (found in ACTOplus Met, Avandamet, Glucophage, Glucovance) and your reflux drug omeprazole (Prilosec) could both contribute to ...

Biovail Reports Fourth Quarter, Year-End 2005 Financial Results Mar 23, 2006
Business Wire (press release), ...expense was $62.3 million, compared with $64.7 million, a decrease that also reflects the final amortization of Biovail's interest in generic omeprazole in the ...

Oscient Pharmaceuticals Reports Financial Results for Fourth ... Mar 6, 2006
Genetic Engineering News, No significant drug-drug interactions were seen with theophylline, digoxin, oral contraceptives, cimetidine, omeprazole, and warfarin, although patients ...

Santarus Reports Fourth Quarter and Full Year 2005 Financial ... Mar 6, 2006
Genetic Engineering News, ...life for patients. The company's products are immediate-release formulations of omeprazole, a widely prescribed PPI. The company ...

Drugs may cause B-12 deficiency Mar 12, 2006
Los Angeles Times, Your diabetes medicine metformin (found in Actoplus Met, Avandamet, Glucophage, Glucovance) and your reflux drug omeprazole (Prilosec) could both contribute to ...

Pharma cos fight pitched battle on patent turf Mar 7, 2006
Hindu Business Line, ...application on Tadalafil and Torrent is opposing Astra Aktiebolag's patent application on a pharmaceutical formulation of ulcer drug Omeprazole, a lawyer said. ...

Paying attention is a must Mar 13, 2006
Thoroughbred Times, ...veterinarians. Both UlcerGard and GastroGard contain omeprazole, considered the gold standard for prevention and treatment of ulcers. ...

Duodenal ulcer tops chart: Study Mar 9, 2006
Newindpress (subscription), ...use of anti-bacterial agents like metronidazole and clarithromycin with strong acid subsidising proton pump inhibitors (PPI) like Omeprazole, Pantoprazole and ...

Santarus to Present at Citigroup Small & Mid-Cap Conference Mar 7, 2006
Business Wire (press release), ...patients. The company's products are immediate-release formulations of omeprazole, a widely prescribed proton pump inhibitor. The ...

Some drugs may change hair color Mar 14, 2006
Asbury Park Press, Your diabetes medicine metformin and your reflux drug omeprazole (Prilosec) could both contribute to lower levels of vitamin B-12. ...

Treatments for acid reflux include higher doses, surgery Dec 20, 2005
Newsday, I'm referring in particular to proton pump inhibitors - esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix) or ...

Reflux Drugs Linked to Rise of Community-Acquired C. Difficile Dec 20, 2005
MedPage Today, Suppression of gastric acid with proton-pump inhibitors drugs like Prilosec (omeprazole) or Nexium (esomeprazole) is associated with a two- to threefold ...

The Investment Column: Yule Catto is still trying to find the ... Dec 14, 2005
Independent, ...no major new products up its sleeve until at least 2007 - which is especially disappointing after drugs including the ulcer-busting Omeprazole produced bumper ...

Bentley Pharmaceuticals' Newly Formed Irish Subsidiary Receives ... Nov 21, 2005
Business Wire (press release), ...capsules of generic omeprazole in Ireland. Omeprazole belongs to a class of proton-pump inhibitors used in the treatment of acid ...

Painkiller Study Aims to Answer Safety Questions Dec 14, 2005
MedPage Today, ...for taking the ethical high ground, said that all patients will be maintained on aspirin for cardiovascular protection and Prilosec (omeprazole) to reduce the ...

AHRQ Releases First Comparative Effectiveness Review; Certain ... Dec 14, 2005
U.S. Newswire (press release), Examples of PPIs include AcipHex(r), Nexium(r), Prevacid(r), Prilosec OTC, and Protonix(r). Generic omeprazole is also available. ...

AHRQ Releases First Comparative Effectiveness Review; Certain ... Dec 14, 2005
Hispanic PR Wire (press release), Examples of PPIs include AcipHex(R), Nexium(R), Prevacid(R), Prilosec OTC, and Protonix(R). Generic omeprazole is also available. ...

Certain Drugs Found as Effective as Surgery for Management of GERD Dec 15, 2005
Community Dispatch (press release) Examples of PPIs include AcipHex®, Nexium®, Prevacid®, Prilosec OTC, and Protonix®. Generic omeprazole is also available. PPIs ...

Drugs as Effective as Surgery for Management of Gerd Dec 16, 2005
Newswise (press release) ...unclear. Examples of PPIs include AcipHex, Nexium, Prevacid, Prilosec OTC, and Protonix. Generic omeprazole is also available. • PPIs ...

Wife battles for identity mix-up man to be freed Dec 16, 2005
Leeds Today, Dr Ellis suggested the risk of perforation would have reduced if Mr Winestein had been given a stomach-protecting drug, Omeprazole. ...

RHM fails to find the ingredients to suit investors' taste Dec 14, 2005
Times Online, The company added that sales at its Pharma and Fine Chemicals division — which makes active ingredients used in omeprazole, a generic version of Prilosec ...

Consilient Health Ltd. Concludes Licensing/Supply Agreement With ... Nov 22, 2005
Market Wire (press release) ...company announced today that it has entered into a non-exclusive agreement with Bentley Pharmaceuticals, Inc., to distribute and market omeprazole, the generic ...

Stomach Acid Rebounds When Ulcer Bug Is Cleared Dec 7, 2005
PakTribune.com, Helicobacter pylori (H. pylori), which in many cases can be eradicated with a combination of antibiotics and a gastric acid suppressor like Prilosec (omeprazole ...

Health Stocks in Motion Nov 21, 2005
TheStreet.com Pharmaceuticals Ireland Ltd, received approval from the Irish Medicines Board to market 10 milligram, 20 mg, and 40 mg capsules of generic omeprazole, a proton ...

Highlights of rising and falling US stocks Nov 21, 2005
Investor's Business Daily (subscription) By Michael Baron. Bentley Pharmaceuticals (BNT) said its newly formed Irish unit received approval to market generic versions of omeprazole in Ireland. ...

Highlights of rising and falling US stocks Nov 21, 2005
Investor's Business Daily (subscription) ...shares ended Monday with a 12.7% gain after the company said its newly formed Irish unit received approval to market generic versions of omeprazole in Ireland. ...

PHO impact seen in subsidised prescribing jump Dec 5, 2005
Scoop.co.nz (press release), ...lowering simvastatin (Lipex) was the second-most prescribed drug with 945,783 prescriptions, surpassing the anti-ulcer and heartburn drug omeprazole (Losec) on ...

New Data on FACTIVE(R) Tablets and Ramoplanin Presented at the ... Dec 9, 2005
Business Wire (press release), No significant drug-drug interactions were seen with theophylline, digoxin, oral contraceptives, cimetidine, omeprazole, and warfarin, although patients ...

NEW AMERICA Dec 7, 2005
Investor's Business Daily (subscription) ...in Spain. One was generic omeprazole, a heartburn drug sold by Procter & Gamble (PG) under the Prilosec brand name. Murphy figures ...

Zydus Cadila gets approval to market Sertraline in France Nov 21, 2005
Hindustan Times, ...last year. These include --- Simvastatin in the cardiovascular segment and Omeprazole in the gastrointestinal segment, it added.

Zydus Cadila gets approval to market Sertraline in France Nov 21, 2005
Hindu Business Line, ...year. These include - Simvastatin in the cardiovascular segment and Omeprazole in the gastrointestin al segment, it added. - PTI.

Why state Medicaid bill is so high Dec 4, 2005
Buffalo News, And Omeprazole for acid reflux costs $3.67 for a capsule in New York and $1.44 in California. Gov. George E. Pataki has tried to control drug costs. ...

Zydus Cadila receives approval for Sertraline from AFSSAPS, France Nov 22, 2005
domain-B, These include two blockbuster products, Simvastatin in the cardiovascular segment and Omeprazole in the gastrointestinal segment. ...

Drug controller gives details of sub-standard medicines Nov 25, 2005
GreaterKashmir.com (press release), 43014 Exp Feb 2006, MK Pharma private Ltd Triputi; Agarol Emulsion, Batch No 420-09212 M Exp dt 7.06 Mfg by Pfizer Ltd; Omeprazole Capsules, Batch No MC 1974 ...

Market Highlights Nov 21, 2005
Winston-Salem Journal, ...up $2.02 to close at $17.92. Bentley gained after it received clearance to sell its heartburn treatment omeprazole in Ireland. • SanDisk Corp. ...

Govt plans 15-35% cap on retail margins of unbranded drugs Nov 18, 2005
Economic Times, ...move is expected to substantially reduce prices of medicines like anti-inflammatory pill nimesulide, allergy medication cetrizine and anti-ulcer drug omeprazole ...


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