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monoclonal antibody anti-alpha V beta 3 integrin
monoclonal antibody anti-alpha V beta 3 integrin
information and resources from the National Cancer Institute
NCI Thesaurus | monoclonal antibody anti-alpha V beta 3 integrin
A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Humanized monoclonal antibody LM609 blocks the binding of ligands, such as vitronectin, to alpha v beta 3 integrin, resulting in inhibition of angiogenesis and metastasis. Alpha v beta 3 integrin is a cell adhesion and signaling receptor that is expressed on the surface of tumor vessel endothelial cells, some tumor cells, and a number of other cell types. NCI Thesaurus | monoclonal antibody anti-alpha V beta 3 integrin
A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Humanized monoclonal antibody LM609 blocks the binding of ligands, such as vitronectin, to alpha v beta 3 integrin, resulting in inhibition of angiogenesis and metastasis. Alpha v beta 3 integrin is a cell adhesion and signaling receptor that is expressed on the surface of tumor vessel endothelial cells, some tumor cells, and a number of other cell types.
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monoclonal antibody anti-alpha V beta 3 integrin
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