|
mitoxantrone hydrochloride
mitoxantrone hydrochloride
information and resources from the National Cancer Institute
NCI Thesaurus | mitoxantrone hydrochloride
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin. NCI Thesaurus | mitoxantrone hydrochloride
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
|
|
|
|
|
|
mitoxantrone hydrochloride
-->
|
