ketoconazole

ketoconazole information and resources from the National Cancer Institute

ketoconazole

A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a-dimethylase, a microsomal cytochrome P450-dependent enzyme, thereby disrupting synthesis of ergosterol, an important component of the fungal cell wall. ketoconazole

A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a-dimethylase, a microsomal cytochrome P450-dependent enzyme, thereby disrupting synthesis of ergosterol, an important component of the fungal cell wall.

news articles



Barrier Therapeutics to Present at CIBC World Markets Annual ... Mar 29, 2006
Market Wire (press release) Barrier's Sebazoleā„¢ (2% ketoconazole) product candidate, for the treatment of seborrheic dermatitis, is currently under FDA review. ...

Topical and Oral Combination Therapy for Toenail Onychomycosis Mar 28, 2006
Journal of the American Podiatric Medical Association GUPTA AK, KOHLI Y: In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in ...

Data Analysis Showed VYTORIN(R) (Ezetimibe/Simvastatin) ... Mar 13, 2006
International News Service, The use of VYTORIN concomitantly with the potent CYP3A4 inhibitors itraconazole, ketoconazole, erythromycin, clarithromycin, telithromycin, HIV protease ...

Connetics Names Doris Boesch Director, Stability Programs; Reports ... Mar 24, 2006
Genetic Engineering News, VersaFoam-EF, 0.05%, a super high-potency topical steroid formulation to treat atopic dermatitis and plaque psoriasis; Extina(R) (ketoconazole) VersaFoam-HF, 2 ...

Study Shows Levitra Treats Erectile Dysfunction Effectively in Men ... Mar 22, 2006
DG News In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended, and ...

ASK THE DOCTOR: Selenium is the first course against dandruff Mar 21, 2006
The Patriot Ledger, ...shampoo Nizoral AD. Nizoral (ketoconazole) used to be available only as prescription but now is over-the-counter. If shampoo alone ...

David E. Cohen, MD, MPH Named to Connetics' Board of Directors ... 21 Dec 2005
Business Wire (press release), VersaFoam-EF, 0.05%, a super high-potency topical steroid formulation to treat atopic dermatitis and plaque psoriasis; and Extina(R) (ketoconazole) VersaFoam-HF ...

MethylGene Unveils HDAC Anti-Fungal Program Dec 16, 2005
Genetic Engineering News, ...two posters, available on MethylGene's web site, presented at ICAAC entitled, "Synergism of Histone Deacetylase (HDAC) Inhibitors with Ketoconazole in Candida ...

Barrier Therapeutics Announces FDA Acceptance of Its New Drug ... Dec 9, 2005
Market Wire (press release) ...announced that the US Food and Drug Administration (FDA) has accepted for filing the Company's New Drug Application (NDA) for Sebazoleā„¢ (ketoconazole USP 2 ...

Other News To Note Dec 9, 2005
TMCnet Barrier Therapeutics Inc., of Princeton, NJ, said the FDA accepted for filing the company's new drug application for Sebazole (ketoconazole) topical gel to ...

FDA accepts Barrier's dermatitis gel for review Dec 12, 2005
Pharmaceutical Business Review ...of seborrheic dermatitis, with less risk for irritation and a more convenient treatment regimen as compared to currently available ketoconazole cream products ...

FIFTH DISEASE: A COMMON CHILDHOOD AILMENT DEAR DR. DONOHUE: Dec 5, 2005
Charlotte Sun-Herald, Among them are nystatin mouthwashes, clotrimazole lozenges, and fluconazole, ketoconazole and itraconazole, all of which come in many forms. ...

Stop being so itchy! Nov 26, 2005
Malaysia Star, Aspirin, certain antibiotics (for example, penicillin, sulphonamides), antifungals (for example, ketoconazole) and narcotics (for example, morphine) are the ...

Dr. Gaff's Column Nov 28, 2005
KPCnews.com, Use of simvastatin (Zocor, Vytorin) with itraconazole (Sporanox), ketoconazole (Nizoral), erythromycin, clarithromycin (Biaxin), telithromycin (Ketek ...


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