interleukin-12
information and resources from the National Cancer Institute
NCI Thesaurus | interleukin-12
A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis. NCI Thesaurus | interleukin-12
A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein-10 (IP-10) and so inhibits tumor angiogenesis.
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news articles
Type I Interferon Production by Tertiary Lymphoid Tissue ... Mar 28, 2006
Am J Pathology (subscription) ...lipogranulomas. Dendritic cells from TMPD lipogranulomas underwent activation/maturation with high CD86 and interleukin-12 expression. ...
Kikkoman Finds Soy Sauce Bacteria Effective Against Allergies Mar 9, 2006
Japan Corporate News (press release), ...that tetragenococcus halophilus Th221, a kind of plant-derived lactic acid bacteria found in soy sauce, can induce the generation of interleukin 12 (IL-12), a ...
Global Experts Convene to Address Emerging Research About ... Mar 22, 2006
Yahoo! News (press release) In addition to the clinical results, Bifidobacterium infantis induced normalization of the interleukin 10/interleukin 12 ratio, involved in inflammation. ...
Gene increases risk of tuberculosis 21 Dec 2005
Biology News Net (press release), But extremely high levels of MCP-1 can be dangerous, as they inhibit the production of another immune protein called interleukin-12. ...
Interleukin-12 can safely be administered with Interferon as an ... Dec 16, 2005
Xagena.it, A study has shown that the immune-stimulating hormone known as Interleukin-12 ( IL-12 ) can safely be administered with Interferon, another immune-system ...
Interleukin with interferon boosts immunity Dec 10, 2005
United Press International 10 (UPI) -- The immune-stimulating hormone known as interleukin-12 -- IL-12 -- can safely be administered with interferon, say Ohio State University researchers ...
Gene Boosts Risk of Tuberculosis Dec 12, 2005
Forbes However, exceedingly high levels of MCP-1 can inhibit production of another immune protein called interleukin-12, which is needed to activate immune cells that ...
Study Shows Combination of Immune Substances to Be Safe Dec 9, 2005
Newswise (press release) Newswise — New research has shown that the immune-stimulating hormone known as interleukin-12 (IL-12) can safely be administered with interferon, another ...
Innovative Research Set To Push Boundaries Of Cancer Care Nov 23, 2005
Science Daily (press release) ...immune system against cancer, researchers have tried a number of different strategies to deliver the powerful immune system stimulant interleukin 12 (IL-12) to ...
Enbrel, Humira to dominate TNF-alpha market Nov 28, 2005
World Peace Herald, Looking several years ahead, Mundy thinks novel cytokine inhibiting agents, such as interleukin-12 inhibitors, could also have an impact on this market. ...
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