interferon gamma
information and resources from the National Cancer Institute
NCI Thesaurus | interferon gamma
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells. NCI Thesaurus | interferon gamma
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells.
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news articles
Anti-inflammatory Effect Of Beer, Blocks Interferon-gamma-induced ... Mar 2, 2006
Medical News Today (press release), Dietmar Fuchs and his team on peripheral mononuclear blood cells show that beer extracts block interferon-gamma-induced chemical processes. ...
Asthma Drug Duo Effective Against COPD Inflammation Mar 31, 2006
MedPage Today, ...significant reductions in CD45+ and CD4+ cells expressing genes for the pro-inflammatory cytokines tumor necrosis factor-alpha and interferon-gamma (P<.03 for ...
American Journal of Respiratory and Critical Care Medicine Vol 173 ... Mar 28, 2006
AJRCCM (subscription), Cho SH, Stanciu LA, Holgate ST, Johnston SL. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4 + and CD8 + T cells in atopic asthma. ...
Good Cell, Bad Cell Mar 23, 2006
Science Now, ...into Mr. Hydes. When good microglia go bad, it's usually because of a protein called interferon gamma (IFN-gamma). Produced by the ...
Beer fights heart disease: official Mar 6, 2006
Register, ...good news for those of you who like a swift pint or two: beer doesn't just fight cancer and make you clever but also blocks "interferon-gamma-induced chemical ...
Senesco's Technology Increases Pancreatic Islet Cell Survivability ... Mar 22, 2006
Genetic Engineering News, In a concurrent study, the investigators showed that death of islets resulting from exposure to IL-1beta and interferon-gamma was also significantly reduced ...
Advanced Biotherapy Signs Memorandum of Understanding with ... Mar 22, 2006
Genetic Engineering News, Its core technology is protected under US patents and patents pending for the use of a class of inhibitors to the cytokines known as interferon-gamma and tumor ...
InterMune to Present at the Bear Biotech West Coast Confab Mar 16, 2006
PR Newswire (press release), The pulmonology portfolio includes Actimmune(R) (interferon gamma-1b), which is being evaluated in the INSPIRE Trial, a Phase III study in patients with IPF ...
Oxford Immunotec Welcomes UK NICE Guideline On Tuberculosis As ... Mar 23, 2006
Medical News Today (press release), ...skin test in the first instance and, if the results are positive, conducting a further blood test (also known as an interferon-gamma immunological test) to ...
Herbal formula silences peanut allergy in mice Mar 8, 2006
Reuters FAHF-2 also appears to stimulate T cells to produce more interferon-gamma, a cytokine that is known to curb allergic responses. ...
Chemotherapy for Immune Disorder Suggested as Avian Flu Treatment Mar 3, 2006
CNN ...and colleagues noted. Both patients had high levels of cytokines, including interleukin-2 and interferon gamma. That finding has ...
Update on tuberculosis -- 2005 Mar 2, 2006
Innovations-Report, ...infection. For detection of possible TB infection, the US Food and Drug Administration has approved a new interferon-gamma blood test. ...
Clinical Data Evaluating CC-10004 As New Oral Therapy in Severe ... Mar 6, 2006
International News Service, ...that inhibits the production of multiple proinflammatory mediators including PDE-4, TNF-alpha, interleukin-2 (IL-2), interferon-gamma, leukotrienes, and nitric ...
CROI: Many patients still gaining CD4 cells after seven years of ... Mar 1, 2006
Aidsmap, ...treatment centre, demonstrated that daily injections with recombinant human growth hormone could increase HIV-specific CD4 and interferon-gamma producing CD8 ...
Let's drink to that: Innsbruck beer research Mar 3, 2006
Science Business (subscription), In research published this week Professor Dietmar Fuchs and his team show that beer extracts block the inflammatory cascade initiated by interferon gamma. ...
Advanced Biotherapy Appoints Daniel Levitt, MD, Ph.D., Former ... Dec 20, 2005
Genetic Engineering News, ...senior level management experience in biotech and pharma drug development, and his knowledge of the mechanism of action of interferon-gamma and other cytokine ...
Advanced Biotherapy Issues Stockholders Newsletter Nov 29, 2005
Business Wire (press release), ..."We are also encouraged by recent, publicly disclosed collaborative relationships targeting the use of antibodies to interferon-gamma to treat certain ...
Roche and Maxygen to Co-Develop Recombinant Factor VIIa ... Dec 14, 2005
Yahoo! News (press release) ...into clinical development in 2006, a novel G-CSF that Maxygen is advancing into clinical development in 2006 and a novel interferon gamma that InterMune is ...
Transgene releases positive Phase I/II data of TG1042 (Ad-IFNg) ... Dec 11, 2005
Canada NewsWire (press release), ...relapsing CBCL. About TG1042: ---- TG1042 uses Transgene's adenovirus vector carrying the human interferon gamma gene. About ...
Transgene Releases Positive Phase I/II Data of TG1042 (Ad-IFNg) ... Dec 11, 2005
Biotech Intelligence (press release), ...treatment of relapsing CBCL. TG1042 uses Transgene's adenovirus vector carrying the human interferon gamma gene. The poster presentation ...
SOCIETY: Wanted: Someone who's driven to help Nov 28, 2005
Peterborough Evening Telegraph, ...in the UK. It appears to be caused by a chemical found naturally in the body called interferon gamma. Under normal circumstances ...
InterMune Divesting Infergen For $135.5M, Cuts Work Force Nov 29, 2005
BioWorld Online (subscription), ...the firm reduces money put into awareness programs related to idiopathic pulmonary fibrosis (IPF), for which InterMune has Actimmune (interferon gamma-1b) in ...
InterMune Sharpens Focus on Key Development Programs and ... Nov 28, 2005
Yahoo! News (press release) InterMune will continue to support the supply and reimbursement of Actimmune® (interferon gamma-1b) for its labeled indications, chronic granulomatous disease ...
(Euronext Paris) - Transgene : Clinical Pipeline Update Nov 29, 2005
Euronext, ...significantly impaired by the treatment. TG1042 uses Transgene’s adenovirus vector carrying the interferon gamma gene. TG4001 uses the MVA ...
RESEARCHERS GET $1.4 GRANT FOR WORK AT UT HEALTH CENTER Nov 23, 2005
Tyler Morning Telegraph, ...at UTHCT's Center for Pulmonary and Infectious Disease Control, will use the National Institutes of Health grant to study how interferon-gamma, a protein that ...
A novel type of T helper cells found to be a key to inflammatory ... Nov 22, 2005
Xagena.it, Although TH1 and TH2 are known to produce powerful cytokines - such as interferon-gamma ( IFN-g ) and allergy-associated interleukin 4 ( IL-4 ), respectively ...
InterMune Elects David S. Kabakoff, Ph.D. To Board Of Directors Dec 1, 2005
PR Newswire (press release), HCV) infections. The pulmonology portfolio includes Actimmune(R) (interferon gamma-1b), pirfenidone and research programs. Actimmune ...
Transgene: Clinical Pipeline Update Nov 29, 2005
PR Newswire (press release), ...by the treatment. About TG1042: TG1042 uses Transgene's adenovirus vector carrying the interferon gamma gene. About TG4001: TG4001 ...
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