infliximab

infliximab information and resources from the National Cancer Institute

NCI Thesaurus | infliximab

A recombinant chimeric, mouse-human monoclonal antibody directed against tumor necrosis factor alpha (TNF-alpha), a protein involved in inflammation, cell survival, and apoptosis. Infliximab may be pro- apoptotic or anti-apoptotic, depending on cell type. NCI Thesaurus | infliximab

A recombinant chimeric, mouse-human monoclonal antibody directed against tumor necrosis factor alpha (TNF-alpha), a protein involved in inflammation, cell survival, and apoptosis. Infliximab may be pro- apoptotic or anti-apoptotic, depending on cell type.



news articles



Remicade (infliximab) gains Australian approval for treatment of ... Mar 23, 2006
News-Medical.net, ...that the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of Remicade (infliximab) to include ...

Moderate To Severe Psoriasis - Remicade® (infliximab) Phase 3 ... Mar 5, 2006
Medical News Today (press release), Phase 3 data show treatment with REMICADE® (infliximab) resulted in rapid, significant improvement and long-term response in patients with moderate to severe ...

International Approvals: Femara and Remicade Mar 27, 2006
Medscape (subscription) Australia's Therapeutic Goods Administration has approved an expanded indication for infliximab, allowing its use with methotrexate for the first-line ...

Use of the Existing Cytokine Therapeutics in Inflammatory ... Mar 31, 2006
Genetic Engineering News, ...disease (CD). Nearly all sales were generated by the three available anti-TNF-a agents: etanercept, infliximab, and adalimumab. Twenty ...

Remicade(R) Approved In Australia For Treatment Of Early ... Mar 24, 2006
Medical News Today (press release), ...the Therapeutic Goods Administration of the Department of Health and Ageing in Australia has revised the indication of REMICADE (R) (infliximab) to include the ...

Drug approved for arthritis treatment Mar 29, 2006
Ninemsn, ...erosion of the joints.". Remicade is a biological treatment whose active ingredient is the human-mouse protein infliximab. It is not ...

First Biologic Therapy Approved in Canada for Painful Inflammatory ... Mar 30, 2006
DG News MONTREAL, CANADA -- March 30, 2006 -- Remicade® (infliximab) is the first biologic approved to treat Canadians living with the debilitating effects of ...

Analysis: Remicade works for psorasis Mar 6, 2006
United Press International SAN FRANCISCO, March 6 (UPI) -- Remicade (infliximab) -- a drug already approved by the Food and Drug Administration for the treatment of rheumatoid arthritis ...

REMICADE(R) Phase 3 Data Show Rapid and Significant Improvement ... Mar 7, 2006
Webbolt Business News (subscription), SAN FRANCISCO -- Phase 3 data show treatment with REMICADE(R) (infliximab) resulted in rapid, significant improvement and long- term response in patients with ...

REMICADE(R) Phase 3 Data Show Rapid and Significant Improvement ... Mar 3, 2006
PR Newswire (press release), SAN FRANCISCO, March 3 /PRNewswire/ -- Phase 3 data show treatment with REMICADE(R) (infliximab) resulted in rapid, significant improvement and long- term ...

REMICADE(R) Phase 3 Data Show Rapid and Significant Improvement ... Mar 3, 2006
PR Newswire (press release), Level, Sustained Response with Maintenance Therapy SAN FRANCISCO, March 3 /PRNewswire/ -- Phase 3 data show treatment with REMICADE(R) (infliximab) resulted in ...

FDA Approves Rituxan for Refractory Rheumatoid Arthritis Mar 1, 2006
MedPage Today, ...in combination with methotrexate in patients with moderate-to-severe RA that has been refractory to treatment with Enbrel (etanercept) or Remicade (infliximab ...

REMICADE(R) Is First Biologic Approved In European Union To Treat ... Mar 9, 2006
Finanzen.net, ...and Schering-Plough Corporation today announced the European Commission has granted approval of REMICADE(R) (infliximab) for the treatment of moderately to ...

Genentech/Biogen Idec: Rituxan further expands its options Mar 2, 2006
Pharmaceutical Business Review ...treatments (DMARDs), followed by the more expensive biologics such as Amgen's Enbrel (etanercept) or Johnson & Johnson's Remicade (infliximab), which are both ...

Business news in brief Mar 10, 2006
Philadelphia Inquirer, Remicade, known by the chemical name infliximab, is the first biologic drug approved in Europe for ulcerative colitis, the companies said. ...

Treating Crohn's Disease Mar 10, 2006
WSOCtv.com, A newer drug, called infliximab (Remicade®) is used to prevent inflammation in patients with moderate to severe Crohn's disease. ...

FDA clears Rituxan for rheumatoid arthritis Mar 1, 2006
Pharma Times (subscription), ...in patients who have not responded to biologic therapy based on tumour necrosis factor blockers, namely Centocor's Remicade (infliximab), Amgen/Wyeth's Enbrel ...

REMICADE(R) Is First Biologic Approved In European Union To Treat ... Mar 9, 2006
Medical News Today (press release), ...and Schering-Plough Corporation (NYSE: SGP) today announced the European Commission has granted approval of REMICADE(R) (infliximab) for the treatment of ...

Genentech, Biogen Idec Gain Approval Of Rituxan In RA Mar 1, 2006
BioWorld Online (subscription), TNF antagonist therapies such as Enbrel (etanercept, from Amgen Inc.), Humira (adalimumab, from Abbott Laboratories) and Remicade (infliximab, from Johnson & ...

Centocor's Remicade achieves rapid results in psoriasis Mar 7, 2006
Pharmaceutical Business Review Findings from the trial, named EXPRESS II, showed that Remicade (infliximab) maintenance therapy every eight weeks resulted in greater long-term skin clearance ...

BAMBOO SPINE, A SPECIAL KIND OF ARTHRITIS Feb 25, 2006
Charlotte Sun-Herald, Pamidronate, a medicine used for osteoporosis, has also been found effective for AS; so have two newer drugs, infliximab and etanercept. DEAR DR. ...

New Drugs Offer More Choices for Psoriasis 21 Dec 2005
Spartanburg Herald Journal (subscription), In late 2002, her longtime dermatologist, Dr. Terry Hadley of Concord, Mass., started her on infusions of infliximab, sold as Remicade, a new so-called ...

Juvenile Arthritis - A Niche In The Market 21 Dec 2005
Pharmaceutical Business Review Juvenile arthritis is the next indication due for approval for blockbuster biologic therapies Remicade (infliximab) and Humira (adalimumab). ...

Infliximab induces remission of ulcerative colitis Dec 7, 2005
Reuters.uk, Reuters Health) - Treatment of moderate-to-severe active ulcerative colitis, a severe inflammatory disease of the colon, with the drug infliximab is associated ...

Landmark Trials Demonstrate Benefits of Remicade (Infliximab) in ... Dec 8, 2005
DG News 2005 -- Landmark studies published today in The New England Journal of Medicine demonstrate the benefits of treatment with Remicade(R) (infliximab) in patients ...

Inquirer Visayas : ‘I am overwhelmed with gratitude’ Dec 16, 2005
INQ7.net, A recently discovered treatment for Ankylosing Spondylitis called Infliximab, can stop the progression of the disease. ... She vowed I’d get Infliximab. ...

IBD: Current and Future Trends Dec 1, 2005
EndoNurse, In 16 of 27 (59 percent) there was no attempt to start steroid sparing medications such as 6-mercaptopurine (6MP), azathioprine, or infliximab. ...

New drugs effective against gout, colitis Dec 8, 2005
Miami Herald, Two new studies showed that the drugs febuxostat and infliximab can help treat gout and colitis. BY LINDA A. JOHNSON. Two novel drug ...

Crohn's Drug Fights Ulcerative Colitis Dec 7, 2005
Forbes ...colitis who are not helped with medications such as cortisone, 5-ASA or azathioprine have a good chance of responding to Remicade [infliximab] and, in that ...

Remicade Effective for Ulcerative Colitis Dec 8, 2005
MedPage Today, 7 - Remicade (infliximab) appears to be an effective option for patients with ulcerative colitis not responding to conventional treatment, according to a pair ...

Study: Remicade eases arthritis pain Nov 17, 2005
myDNA.com, ...two-year treatment duration, show a significantly higher proportion of patients with active psoriatic arthritis receiving Remicade (infliximab) achieved and ...

New drugs effective against gout, colitis Dec 7, 2005
MSNBC Infliximab, sold under the brand name Remicade for arthritis and Crohn’s disease, was shown to sharply reduce bloody diarrhea, abdominal cramps and other ...

Landmark Trials Published in New England Journal of Medicine ... Dec 7, 2005
PR Newswire (press release), Landmark studies published today in The New England Journal of Medicine demonstrate the benefits of treatment with REMICADE(R) (infliximab) in patients with ...

Studies: Drugs Help Against Gout, Colitis Dec 10, 2005
Brocktown News, Infliximab, sold under the brand name Remicade for arthritis and Crohn‘s disease, was shown to sharply reduce bloody diarrhea, abdominal cramps and other ...

Active psoriatic arthritis patients on REMICADE® achieve major ... Nov 19, 2005
Medical News Today (press release), ...two-year treatment duration, show a significantly higher proportion of patients with active psoriatic arthritis receiving REMICADE® (infliximab) achieved and ...

Trials Published in NEJM Demonstrate Benefits of REMICADE® in ... Dec 7, 2005
EndoNurse, NJ -- Landmark studies published today in The New England Journal of Medicine demonstrate the benefits of treatment with REMICADE® (infliximab) in patients ...

Anti-TNF Drugs Cut Mortality Rates among Rheumatoid Arthritis ... Nov 18, 2005
DG News Suppression of TNF proteins with infliximab (Remicade), etanercept (Enbrel) and adalimumab (Humira), and ensuing reductions of joint inflammation has made ...

ACR Rituxan Shows Durable Response for Refractory RA Nov 18, 2005
MedPage Today, ...trial. He added that infusion reactions were slightly less with Rituxan than what has been observed for Remicade (infliximab). Using ...

ACR: CNTO-148 Demonstrates Efficacy for RA Nov 18, 2005
MedPage Today, That positive finding from a dose-finding study suggests that the drug may be a good alternative to Remicade (infliximab), which is made by Johnson & Johnson ...


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