indole-3-carbinol

indole-3-carbinol information and resources from the National Cancer Institute

indole-3-carbinol

A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, a natural compound present in a wide variety of plant food substances including members of the family Cruciferae with antioxidant and potential chemopreventive properties. Indole-3-carbinol scavenges free radicals and induces various hepatic cytochrome P450 monooxygenases. Specifically, this agent induces the hepatic monooxygenase cytochrome P4501A1 (CYP1A1), resulting in increased 2-hydroxylation of estrogens and increased production of the chemoprotective estrogen 2-hydroxyestrone. indole-3-carbinol

A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, a natural compound present in a wide variety of plant food substances including members of the family Cruciferae with antioxidant and potential chemopreventive properties. Indole-3-carbinol scavenges free radicals and induces various hepatic cytochrome P450 monooxygenases. Specifically, this agent induces the hepatic monooxygenase cytochrome P4501A1 (CYP1A1), resulting in increased 2-hydroxylation of estrogens and increased production of the chemoprotective estrogen 2-hydroxyestrone.

news articles



“Pure Prescriptionsâ€? For Health and Vitality Dec 13, 2005
vision magazine, ...cruciferous vegetables like broccoli, Brussels sprouts, cauliflower, cabbage, and kale (which all contain phytonutrients indole-3-carbinol (I3C), diindolyl ...

“Pure Prescriptionsâ€? For Health and Vitality Dec 13, 2005
vision magazine, ...cruciferous vegetables like broccoli, Brussels sprouts, cauliflower, cabbage, and kale (which all contain phytonutrients indole-3-carbinol (I3C), diindolyl ...


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