homoharringtonine

homoharringtonine information and resources from the National Cancer Institute

NCI Thesaurus | homoharringtonine

A cytotoxic plant alkaloid isolated from the evergreen tree Cephalotaxus with potential antineoplastic activity. Homoharringtonine binds to the 80S ribosome in eukaryotic cells and inhibits protein synthesis by interfering with chain elongation. This agent also induces differentiation and apoptosis in some cancer cell types.NCI Thesaurus | homoharringtonine

A cytotoxic plant alkaloid isolated from the evergreen tree Cephalotaxus with potential antineoplastic activity. Homoharringtonine binds to the 80S ribosome in eukaryotic cells and inhibits protein synthesis by interfering with chain elongation. This agent also induces differentiation and apoptosis in some cancer cell types.

FDA Orphan Drug Approvals: Ceflatonin, Valortim, TQ-1018 Mar 31, 2006
Medscape (subscription) March 31, 2006 — The US Food and Drug Administration (FDA) has approved orphan drug status for homoharringtonine in the treatment of chronic myeloid leukemia ...

New Preclinical Research Supports Ceflatonin in Treatment of Acute ... Mar 23, 2006
DG News ...announced today the publication of pre-clinical research supporting the expansion of its clinical development of Ceflatonin (homoharringtonine) to include ...

New Preclinical Research Supports Ceflatonin(R) in Treatment of ... Mar 22, 2006
International News Service, ...of Dr Jean-Pierre Marie of the Universite Pierre et Marie Curie in Paris which elaborates on the cellular mode of action of homoharringtonine, or "sHHT ...

New Preclinical Research Supports Ceflatonin in Treatment of Acute ... Mar 23, 2006
PharmaLive.com (press release), ...of Dr Jean-Pierre Marie of the Université Pierre et Marie Curie in Paris which elaborates on the cellular mode of action of homoharringtonine, or "sHHT ...

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