flutamide
information and resources from the National Cancer Institute
flutamide
A toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression. flutamide
A toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression.
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news articles
Medical Hair Restoration Mar 27, 2006
DailyIndia.com, Medical hair restoration with flutamide has shown improvement as hair loss restoration treatment in women with hirsutism. For hyperandrogenic ...
Select AIDS, cancer drugs to become cheaper Mar 2, 2006
Sify, ...drugs expected to see a downward price revision are cisplatin, cytosine arabinoside, danazol, daunorubicin HCL, etoposide, flutamide, ondansetron, pacitaxel ...
Managing Treatment-Resistant OCD Mar 14, 2006
Psychiatric Times, Altemus M, Greenberg BD, Keuler D et al. (1999), An open trial of flutamide in the treatment of obsessive-compulsive disorder. J Clin Psychiatry 60(7):442-445. ...
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