etoposide phosphate

etoposide phosphate information and resources from the National Cancer Institute

NCI Thesaurus | etoposide phosphate

A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent. NCI Thesaurus | etoposide phosphate

A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent.

Etopophos

Management of refractory testicular tumors and small cell lung cancer.

Bristol-Myers Squibb Feb 27 1998

Etopophos

Management of refractory testicular tumors, in combination with other approved chemotherapeutic agents.

Bristol-Myers Squibb May 17 1996

Etopophos

Management of small cell lung cancer, first-line, in combination with other approved chemotherapeutic agents.

Bristol-Myers Squibb May 17 1996

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