estramustine

estramustine information and resources from the National Cancer Institute

NCI Thesaurus | estramustine

A synthetic molecule combining estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects. NCI Thesaurus | estramustine

A synthetic molecule combining estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects.

Emcyt

palliation of prostate cancer

Pharmacia & Upjohn Company Dec 24 1981

Positive Findings From Clinical Studies of QUADRAMET(R) in ... Feb 27, 2006
International News Service, ...with castration-refractory bone metastases from prostate cancer with response or stabilization after induction docetaxel-estramustine: Preliminary results.". ...

Positive Findings from Clinical Studies of Quadramet in Prostate ... Feb 27, 2006
DG News With Castration-Refractory Bone Metastases From Prostate Cancer With Response or Stabilization After Induction Docetaxel-Estramustine: Preliminary Results. ...

Taxol® and Paraplatin® Superior to Novantrone® for Hormone ... Mar 10, 2006
Cancer Consultants (press release), ...cancer. However, until recently Novantrone was the drug of choice. The new standard may be Taxotere and Emcyt® (estramustine). The ...

Positive Findings from Clinical Studies of QUADRAMET in Prostate ... Feb 27, 2006
PharmaLive.com (press release), ...in patients with progressive hormone refractory prostate cancer with response or stabilization after induction therapy with docetaxel plus estramustine. ...

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