doxorubicin
information and resources from the National Cancer Institute
doxorubicin
An anthracycline antineoplastic antibiotic isolated from the fungus Streptococcus peucetius var. caesius. Doxorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. The hydrochloride salt doxorubicin hydrochloride is the therapeutic form of doxorubicin.
Adriamycin, Rubex Pharmacia & Upjohn Company Aug 07 1974
Adriamycin PFS Injectionintravenous injection
Antibiotic, antitumor agent.
Pharmacia & Upjohn Company Dec 23 1987
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news articles
Genentech and Biogen seek wider Rituxan use 01 Apr 2006
Pharmaceutical Business Review Rituxan in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) or other anthracycline-based chemotherapy was approved in February ...
Flavonoid research may aid citrus growers Mar 31, 2006
Capital Press (subscription), India indicates that the flavonoid naringenin, which is found in all citrus fruits, may reduce the toxicity of treatments which use the antibiotic doxorubicin. ...
ICE Plus CAV Intensification Promising for High Risk Ewing’s ... Mar 31, 2006
Cancer Consultants (press release), ...that an induction regimen of ifosfamide, carboplatin and etoposide (ICE) followed by intensification with cyclophosphamide, doxorubicin, and vincristine ...
BioAlliance Pharma Announces 2005 Financial Results Mar 31, 2006
Business Wire (press release), The first company product utilizing Transdrug technology, doxorubicin Transdrug, uses doxorubicin, a powerful chemotherapeutic agent indicated for many types ...
Patients with NHL Treated with Anthracyclines at Long-Term Risk ... Mar 27, 2006
Cancer Consultants (press release), ...for Research on Treatment of Cancer (EORTC) have reported that patients with non-Hodgkin lymphoma (NHL) who receive six cycles of doxorubicin have an increased ...
Arsenic Trioxide Effective as Single Agent in Newly Diagnosed APL Mar 31, 2006
Cancer Consultants (press release), Standard initial treatment for APL consists of chemotherapy, including an anthracycline (doxorubicin, epirubicin, mitoxantrone, idarubicin) and the agent all ...
Ecopia Presents Data Highlighting the Potential of Decipher'R' ... Mar 29, 2006
CCNMatthews (press release), The source is soil-dwelling microorganisms that have produced several potent anticancer agents such as doxorubicin, bleomycin and mitomycin. ...
Pixantrone Combination Regimen Produces High Rates of Complete ... Mar 22, 2006
PR Newswire (press release), ...to determine the maximum tolerated dose and evaluate the drug's effectiveness in a combination known as CPOP, in which pixantrone replaces doxorubicin in the ...
Cancer Cells Lose Drug Resistance Following Electrical Stimulation ... Mar 17, 2006
Science Daily (press release) Cancer reveals that treating drug-resistant tumour cells with electric pulses in vitro restores the cells' ability to take up the anti-cancer drug doxorubicin. ...
Patients with NHL Treated with Anthracyclines at Long-Term Risk ... Mar 23, 2006
Cancer Consultants (press release), ...article recently published in the journal Blood, patients with aggressive non-Hodgkin’s lymphoma who receive six cycles of Adriamycin® (doxorubicin) have an ...
Pro-Pharmaceuticals Completes Patient Enrollment in Stage 1 of ... Mar 30, 2006
Genetic Engineering News, ...and pre-clinical studies with its lead product candidate, DAVANAT(R), in combination with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel ...
Rapid Nano Molding Mar 28, 2006
MIT Technology Review, Researchers led by DeSimone created the nanoparticles out of a polymer and a cancer drug such as doxorubicin, forming 200 nanometer-sized particles -- about ...
Genentech applies for new Rituxan use Mar 30, 2006
BusinessWeek Additionally, the application covers the use of Rituxan along with the chemotherapy combination cyclophosphamide, doxorubicin, vincristine and prednisone in ...
Electrical Stimulation Reverses Drug Resistance in Cancer Cells Mar 22, 2006
Cancerpage.com, ...from the Cleveland Clinic Lerner College of Medicine, tested the ability of electrical stimulation to improve the response to doxorubicin in several tumor cell ...
Matrix Metalloproteinase Inhibitor Effective for Kaposi’s ... Mar 22, 2006
Cancer Consultants (press release), Patients with AIDS-related Kaposi’s sarcoma are initially treated with Doxil (liposomal doxorubicin) or combination chemotherapy with doxorubicin, bleomycin ...
Cell Therapeutics shows pixantrone data Mar 22, 2006
BusinessWeek The CHOP regimen uses the drugs cyclophosphamide, vincristine, prednisone and doxorubicin. Cell Therapeutics replaced doxorubicin ...
Neoadjuvant Aromatase Inhibitors May Be as Effective as ... Mar 27, 2006
DG News In the chemotherapy group, 118 patients received 60 mg/m 2 of doxorubicin and 200 mg/m 2 of paclitaxel every 3 weeks for 4 cycles. ...
Electricity Shocks Drug-Resistant Tumor Cells into Sensitivity Mar 17, 2006
MedPage Today, ...stimulation was applied to cancer cell lines that overexpress the MDR1 gene, which makes them resistant to drugs such as Adriamycin (doxorubicin), Dr. Janigro ...
Single-Agent Arsenic Trioxide Very Effective for Treatment of APL Mar 27, 2006
Cancer Consultants (press release), Consolidation in all arms was doxorubicin, cytarabine, and homoharrington administered sequentially followed by ATRA maintenance. ...
FDA Approvals: Aranesp, Taxotere, Leukine Mar 28, 2006
Medscape (subscription) ...the treatment of locally advanced or metastatic breast cancer after failure of prior chemotherapy, and for adjuvant use with doxorubicin and cyclophosphamide ...
Committee for Medicinal Products for Human Use Post-authorisation ... Mar 24, 2006
PharmaLive.com (press release), Taxotere (docetaxel) in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with operable node- positive ...
Alfacell achieves full patient enrollment for Onconase phase IIIb ... Mar 28, 2006
Therapeutics Daily (subscription) (press release), ...in the Onconase UMM study, including newly-diagnosed and refractory patients treated with Onconase as a single agent and in combination with doxorubicin. ...
Doxil® in the VAD Regimen for Myeloma Confirmed Less Toxic Than ... Feb 28, 2006
Cancer Consultants (press release), A US multicenter trial has reported that a regimen of Doxil (pegylated liposomal doxorubicin), vincristine and dexamethasone is associated with less toxicity ...
Hong Kong firm makes new bid for Onyx Software Mar 23, 2006
Seattle Times, Cell Therapeutics replaced doxorubicin with the investigational drug pixantrone and found that up to 77 percent of patients responded to the treatment. ...
Wielding heat as a weapon Mar 19, 2006
Los Angeles Times, Mixed in with the water is a chemotherapy drug, doxorubicin. The liposome is designed to be stable at body temperature but to burst when heated. ...
Pro-Pharmaceuticals' Abstract Accepted for Publication in ASCO ... Mar 17, 2006
International News Service, The Company has been conducting clinical and pre-clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ...
Electrical Stimulation may Improve Cancer Treatment Mar 19, 2006
Ivanhoe, ...out using samples of both rat and human tumor cells that were over-expressing a certain protein that was making them fight off the chemotherapy drug doxorubicin ...
Callisto Pharma Expands Research Trial Of Cancer Drug L-Annamycin ... Mar 21, 2006
Trading Markets, ...drugs in clinical use today. Compounds in this class include doxorubicin, daunorubicin and epirubicin. These drugs are all close ...
Neoadjuvant Sarcoma Chemotherapy Results in High Toxicity Levels Mar 1, 2006
Cancerpage.com, The patients received three cycles of neoadjuvant modified mesna, doxorubicin, ifosfamide and dacarbazine (MAID), interdigitated radiotherapy and following ...
Interlocutory Injunctions for Pharmaceutical Patent Infringement Mar 15, 2006
Mondaq News Alerts, Under that licence, Pfizer manufactures and sells ready-to-use solutions of doxorubicin hydrochloride and epirubicin hydrochloride. ...
TAXOTERE(R) Receives US FDA Approval For Use In Advanced Stomach ... Mar 23, 2006
Yahoo! News (press release) ...locally advanced or metastatic breast cancer after failure of prior chemotherapy, * TAXOTERE® is approved in combination with doxorubicin and cyclophosphamide ...
Taxotere®/Platinol®/Herceptin® Effective in Locally Advanced ... Mar 22, 2006
Cancer Consultants (press release), ...were treated with initial Taxotere/cisplatin/Herceptin followed by surgery, followed by subsequent chemotherapy including Adriamycin® (doxorubicin) and Cytoxan ...
Temodar® and Thalomid® Effective for Metastatic Neuroendocrine ... Mar 21, 2006
Cancer Consultants (press release), ...response rates are low and some of the agents studied include 5-fluorouracil, BiCNU® (carmustine), CeeNU® (lomustine), doxorubicin, dacarbazine and Zanosar. ...
AIDS-related Lymphoma Outcome Improved By Combination Therapy Mar 2, 2006
Medical News Today (press release), They are treated with chemotherapy, often consisting of a multi-drug regimen using cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP). ...
CHOP Plus HAART Safe and Effective for AIDS-Related Lymphomas Mar 13, 2006
Cancer Consultants (press release), 2001. Patients were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in addition to concomitant HAART. ...
Alfacell Achieves Full Patient Enrollment Milestone for the ... Feb 27, 2006
PR Newswire (press release), ...in the ONCONASE UMM study, including newly-diagnosed and refractory patients treated with ONCONASE as a single agent and in combination with doxorubicin. ...
NCCN: Cancer Network Develops Guidelines for Breast Cancer in ... Mar 13, 2006
CNN During pregnancy, patients have usually been treated with combinations of Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), and fluorouracil. ...
FDA Approves Rituxan (Rituximab), the First Targeted B-Cell ... Mar 1, 2006
DG News In addition, Rituxan received FDA approval in February 2006 for the treatment of DLBCL in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ...
Sachs Associates 5th Annual North American Forum: Investing & ... Mar 9, 2006
TMCnet In addition to HyCAMP(TM), Meditech has taken the anti-cancer products HyDOX(TM) (doxorubicin and hyaluronic acid) and HyFIVE(TM) (5-fluorouracil and ...
Analysis:Pregnancy and breast cancer Mar 10, 2006
United Press International During pregnancy, patients have usually been treated with combinations of doxorubicin, cyclophosphamide and fluorouracil - potent anti-cancer drugs.
Q&A: Breast Cancer During Pregnancy Mar 6, 2006
CancerWise The treatment is called FAC chemotherapy (5-flurouracil, doxorubicin, and cyclophosphamide). The chemotherapy was given during the second and third trimesters. ...
First Guidelines for Treatment of Breast Cancer During Pregnancy ... Mar 13, 2006
DG News ...offered. During pregnancy, patients have usually been treated with combinations of doxorubicin, cyclophosphamide and 5-fluorouracil. ...
Simultaneous HIV therapy and chemotherapy for lymphoma effective ... Feb 28, 2006
Aidsmap, German doctors wished to assess the safety and efficacy of using combined chemotherapy consisting of cyclophosamide, doxorubicin, vincristine and prednisone at ...
International Approvals: Rotarix, Hycamtin, Pulmicort HFA Mar 6, 2006
Medscape (subscription) Results of the first study showed topotecan to be similarly effective to a 3-drug regimen (cyclophosphamide, doxorubicin, and vincristine [CAV]) with respect ...
ImClone’s Erbitux Receives FDA Label In Head And Neck Cancer Mar 2, 2006
BioWorld Online (subscription), ...backed away from its takeover of Indianapolis-based device maker Guidant Corp., and might be looking for an oncology drug to market with its Doxil (doxorubicin ...
Less Toxic Chemotherapy Regimen for Metastatic Urothelial Cancer ... Mar 15, 2006
Cancer Consultants (press release), ...chemotherapy drugs. One commonly used chemotherapy regimen is M-VAC (methotrexate, vinblastine, doxorubicin, and cisplatin). Though ...
Neoadjuvant Chemotherapy and Radiotherapy Promising for Large Soft ... Mar 3, 2006
Cancer Consultants (press release), All were scheduled to receive neoadjuvant concomitant radiotherapy and chemotherapy with MAID (mesna, ifosfamide, doxorubicin and dacarbazine). ...
Avastin® Adriamycin Combination for Soft Tissue Sarcoma Mar 8, 2006
Cancer Consultants (press release), A multicenter trial has suggested that the addition of Avastin (bevacizumab) to Adriamycin (doxorubicin) improves outcomes of patients with metastatic soft ...
Genentech, Biogen Idec Gain Approval Of Rituxan In RA Mar 1, 2006
BioWorld Online (subscription), ...combination agent in diffuse large B-cell, CD20-positive, non-Hodgkin’s lymphoma in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ...
Combo Therapy Fights AIDS-Linked Lymphoma Feb 27, 2006
Forbes ...study included 72 HIV patients with AIDS-related lymphoma treated with a multi-drug chemotherapy called CHOP (cylcophosphamide, doxorubicin, vincristine, and ...
Celsion Announces 1-for-15 Reverse Stock Split; Stockholder ... Feb 27, 2006
Genetic Engineering News, We have demonstrated our ability to initiate and execute a development program for our heat activated liposomal doxorubicin drug, ThermoDox(TM), including ...
CHOP Plus HAART Improves Outcome of AIDS-Related Lymphoma Feb 28, 2006
Cancerpage.com, NEW YORK FEB 27, 2006 (Reuters Health) - In patients with AIDS-related lymphoma, combined treatment with cyclophosphamide, doxorubicin, vincristine, and ...
Patients with Unfavorable Risk Hodgkin’s Lymphoma May Not ... 21 Dec 2005
Cancer Consultants (press release), ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is the most commonly used chemotherapy regimen for Hodgkin’s lymphoma. ...
Dose-Dense Chemotherapy Safe and Effective; Particularly for ... 21 Dec 2005
Cancer Consultants (press release), Patients received the study drugs Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide), either concurrently, or sequentially in ...
Silent Night, holy night, all is calm, all is bright… 21 Dec 2005
HoweStreet.com, The researchers are currently working to conjugate two other drugs, paclitaxol and doxorubicin, but they also plan to use proapoptotic peptides and other small ...
Neoadjuvant Docetaxel, Doxorubicin and Capecitabine Used in Women ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- The neoadjuvant combination of docetaxel (T), doxorubicin (A) and capecitabine (X) has demonstrated an encouraging ...
Dose Dense Doxorubicin-Docetaxel Combination Comparable to ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- The pre-operative sequential combination of doxorubicin plus cyclophosphamide administered over four cycles followed by ...
Patients With Unfavorable Risk Hodgkin’s Lymphoma May Not ... Dec 19, 2005
Cancer Consultants (press release), ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine) is the most commonly used chemotherapy regimen. BEACOPP (bleomycin, etoposide ...
Interim Analysis of Phase 3 Study Shows Taxotere (docetaxel)-Based ... Dec 16, 2005
DG News ...in the adjuvant setting with the addition of Herceptin(R) to either of two Taxotere(R)- containing chemotherapy regimens, with or without doxorubicin, in this ...
Breast Cancer Treatment Dec 16, 2005
Food Consumer, 3. Paik S, Bryant J, Park C, et al.: erbB-2 and response to doxorubicin in patients with axillary lymph node-positive, hormone receptor-negative breast cancer. ...
Pilot Study Shows Abraxane Safe and Effective in Sequence with ... Dec 13, 2005
DG News In the study, treatment consisted of dose-dense doxorubicin and cyclophosphamide (AC) every 2 weeks over 4 cycles, followed by Abraxane 260 mg/m 2 every 2 ...
Source: sanofi-aventis Dec 8, 2005
Yahoo! News (press release) ...in the adjuvant setting with the addition of HERCEPTIN® to either of two TAXOTERE®- containing chemotherapy regimens, with or without doxorubicin, in this ...
Rituxan® and CHOP for Elderly Patients with Diffuse Large B-Cell ... Dec 19, 2005
Cancer Consultants (press release), Researchers in Germany have reported that six cycles of Rituxan® (rituximab) and CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), given ...
Little Difference between Docetaxel and Paclitaxel in Treating ... Dec 14, 2005
DG News Never before released data show that there is virtually no difference in disease-free survival when a regimen comprising doxorubicin and cyclophosphamide is ...
(PRN) New Study Demonstrates Nonanthracycline Adjuvant Regimen TC ... Dec 11, 2005
Houston Chronicle, TC (Docetaxel/Cyclophosphamide, 4 cycles) produced a superior disease-free survival compared to four cycles of standard AC (Doxorubicin/Cyclophosphamide) in ...
Adjuvant Therapy with Taxotere® and Cytoxan® Improves Breast ... Dec 13, 2005
Cancer Consultants (press release), Compared to the standard chemotherapy combination of Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide), adjuvant therapy with Taxotere® (docetaxel ...
C-myc Gene Influences Response to Herceptin® Dec 14, 2005
Cancer Consultants (press release), The researchers evaluated patients in the NSABP B-31 clinical trial, which compared treatment with AC-T (doxorubicin,cyclophosphamide,paclitaxel) to treatment ...
First Line Treatment with Herceptin Improves Outcomes in Early ... Dec 9, 2005
DG News ..."At 23 month median follow-up, doxorubicin plus cyclophosphamide and docetaxel and trastuzumab and the regimen of trastuzumab, carboplatin and docetaxel ...
Chemo After Surgery Extends Life in Advanced Endometrial Cancer Dec 9, 2005
Cancerpage.com, NEW YORK DEC 09, 2005(Reuters Health) - For women with advanced endometrial cancer, the combination of doxorubicin and cisplatin after surgery significantly ...
Dose-Dense Chemotherapy Safe and Effective—Particularly for ... Dec 13, 2005
Cancer Consultants (press release), Patients were first randomly assigned to receive concurrent Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide) or concurrent ...
Taxotere® Vs. Taxol® in Adjuvant Treatment of Breast Cancer Dec 14, 2005
Cancer Consultants (press release), Taxotere® (docetaxel) and Taxol® (paclitaxel) produce similar outcomes when given after Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide) in the ...
Chemotherapy after surgery extends survival for patients with ... Dec 5, 2005
EurekAlert (press release), ...rate of recurrence and overall survival between 194 women with advanced endometrial cancer who received chemotherapy with the drugs doxorubicin and cisplatin ...
Taxane-Based Breast Cancer Treatment Cost-Effective Compared to 5 ... Dec 13, 2005
DG News TX -- December 13, 2005 -- Despite higher drug costs and more adverse effects, researchers say a combination of docetaxel, doxorubicin and cyclophosphamide (TAC ...
Taxotere/Cyclophosphamide Offers Greater Disease-Free Survival for ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- The combination of docetaxel (Taxotere) and cyclophosphamide should replace doxorubicin (Adriamycin)/cyclophosphamide ...
cMyc Amplification Confers Increased Activity with the Addition of ... Dec 13, 2005
Cancer Consultants (press release), The researchers evaluated patients enrolled in the NSABP B-13 trial in which AC-T (doxorubicin, cyclophosphamide, paclitaxel) was compared with AC-TH ...
Chemotherapy Extends Survival for Endometrial Cancer Patients Dec 7, 2005
Ivanhoe, A new study reveals the drugs doxorubicin and cisplatin reduce the risk of recurrence by 29 percent and extend survival by 32 percent compared to women who had ...
Non-Anthracycline Chemotherapy Regimen Plus Herceptin®: Effective ... Dec 13, 2005
Cancer Consultants (press release), Phase III Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed by Docetaxel (AC-T) with Doxorubicin and Cyclophosphamide Followed by Docetaxel ...
Immunomedics Reports Preclinical Results on New Therapeutic Dec 15, 2005
Yahoo! News (press release) ...anti-CD74 antibody has shown therapeutic activity in lymphoma and myeloma transplants as a naked (unconjugated) antibody, conjugated with doxorubicin, and now ...
Taxotere®/Cytoxan® Superior to Standard Adriamycin®/Cytoxan as ... Dec 14, 2005
Cancer Consultants (press release), ...combination Taxotere (docetaxel) plus Cytoxan (cyclophosphamide) provides superior results to the standard Adriamycin (doxorubicin)/ Cytoxan regimen as ...
Researchers study breast cancer therapy Dec 15, 2005
myDNA.com, Taxotere (docetaxel) and Cytoxan (cyclophosphamide) improves disease-free survival rates by 33 percent over therapy using Adriamycin (doxorubicin) and Cytoxan. ...
Professor Peter van Brummelen and Dr. Annick Schwebig Join the ... Dec 14, 2005
PR Newswire UK (press release), The company's therapeutic candidates DTS-301, a novel paclitaxel formulation and DTS-201, a doxorubicin prodrug, respectively entered Phase II and Phase I ...
Zevalin Used in Abbreviated Chemotherapy Regimen Shows Efficacy ... Dec 16, 2005
DG News CHOP-R comprises a combination of rituximab (Mabthera(R)), cyclophosphamide, doxorubicin, (Adriamycin(R)), vincristine (Oncovin(R)) and prednisolone. ...
2005 Annual Radiological Society of North America Meeting Nov 30, 2005
Business Wire (press release), ...first study to be presented by Victor Frenkel, PhD of the National Institutes of Health (NIH), ThermoDox (heat sensitive liposomal doxorubicin) administered in ...
Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast Cancer ... Dec 9, 2005
PR Newswire (press release), Pilot Study of Dose-Dense Doxorubicin plus Cyclophosphamide Followed by ABI-007 (ABRAXANE) in Patients with Early-Stage Breast Cancer Nicholas Robert, MD, US ...
Studies favor breast-cancer drug Dec 9, 2005
Seattle Times, Women got one of three regimens: standard treatment with Adriamycin (an anthracycline also known as doxorubicin) and carboplatin followed by Taxotere; standard ...
(PRN) Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast ... Dec 9, 2005
Houston Chronicle, Preliminary results from a phase II trial showed that dose-dense therapy with doxorubicin (Adriamycin(R)) (A) plus cyclophosphamide (Cytoxan(R)) (C) followed ...
Two Drugs Boost Endometrial Cancer Survival Dec 6, 2005
ABC News 6 (HealthDay News) — The use of two drugs, doxorubicin and cisplatin, given after surgery, may help women battling advanced endometrial cancer, new research ...
Chemo after surgery extends life in endometrial cancer Dec 9, 2005
Reuters.uk, ...the study investigators compared recurrence rates and overall survival between 194 women randomized to 5 months of chemotherapy with doxorubicin and cisplatin ...
Innovative Research Set To Push Boundaries Of Cancer Care Nov 23, 2005
Science Daily (press release) Both of these compounds resemble the well-known anticancer chemotherapy drug doxorubicin, but have properties that are also unique, according to Priebe. ...
Cephalon, Inc. Announces Agreement to Acquire Zeneus Holdings ... Dec 5, 2005
PR Newswire UK (press release), ...will accelerate Cephalon's entry into the European oncology market with several commercialized products, including Myocet(R) (liposomal doxorubicin), a cardio ...
FDA Grants Priority Review to Taxotere for the Supplemental New ... Dec 2, 2005
PharmaLive.com (press release), ...locally advanced or metastatic breast cancer after failure of prior chemotherapy, and it is also approved in combination with doxorubicin and cyclophosphamide ...
Herceptin OK as upfront cancer drug Dec 9, 2005
Monsters and Critics.com, Cancer Center, Los Angeles, said there was a repetition of previous observations that the combination of Herceptin and doxorubicin (Adriamycin) could cause ...
Human Genome Sciences Reports Results of Phase 2 Clinical Trial of ... Dec 12, 2005
Yahoo! News (press release) The preclinical data also demonstrate that HGS-ETR1 enhances the tumor-killing activity of bortezomib and doxorubicin.(2) Further study of HGS-ETR1 in ...
Rituximab maintenance therapy dramatically improves survival in ... Dec 13, 2005
RxPG NEWS, ...trial, 465 patients with relapsed and refractory indolent NHL were randomised to receive either 3-weekly cyclophosphamide, doxorubicin, vincristine, and ...
Ritalin Conjugate Used to Treat "Chemo-Brain" in Breast Cancer ... Dec 13, 2005
DG News The most commonly used regimens were cyclophosphamide, doxorubicin, paclitaxel, 5-fluorouracil, methotrexate, docetaxel and carboplatin. ...
(PRN) - Telik's TELINTRA Demonstrates Positive, Clinically ... Dec 11, 2005
Bolsamania.com, New Study Demonstrates Nonanthracycline Adjuvant Regimen TC (Docetaxel and Cyclophosphamide) Is Superior to Standard AC (Doxorubicin/Cyclophosphamide) for ...
Trastuzumab Used as First Line Therapy in Women Whose Cancer Has ... Dec 12, 2005
DG News ...real-life" study. Such agents included paclitaxel and docetaxel, vinorelbine, capecitabine cisplatin and doxorubicin. lead author ...
SABCS: Taxotere-Cytoxan Combo Shows Survival Advantage in Breast ... Dec 12, 2005
MedPage Today, Taxotere (docetaxel) and Cytoxan (cyclophosphamide) delivers 33% better disease-free survival than the standard regimen of Adriamycin (doxorubicin) and Cytoxan ...
VELCADE(R) (bortezomib) for Injection Continues to Show Impressive ... Dec 12, 2005
PR Newswire (press release), ...with CHOP Plus Rituximab (abstract #491) Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and ...
Pro-Pharmaceuticals Announces Two International Clinical Sites in ... Dec 13, 2005
Genetic Engineering News, The Company has been conducting pre-clinical and clinical studies with 5-FU, leucovorin, irinotecan, doxorubicin, oxaliplatin, paclitaxel, cisplatin, and ...
SABCS: No Differences Found In Taxane Treatment Results Dec 9, 2005
MedPage Today, ...disease. All patients received four cycles of Adriamycin (doxorubicin) and Cytoxan (cyclophosphamide) before the taxane therapy. ...
VELCADE (bortezomib) for Injection Continues to Show Impressive ... Dec 13, 2005
PharmaLive.com (press release), Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) plus rituximab for the ...
Maintenance therapy with RITUXAN(R) dramatically improves survival Dec 12, 2005
CNW Telbec (Communiqués de presse), ...trial, 465 patients with relapsed and refractory indolent NHL were randomised to receive either three- weekly cyclophosphamide, doxorubicin, vincristine, and ...
Chemotherapy Lengthens Survival in Advanced Endometrial Carcinoma Dec 6, 2005
MedPage Today, 6 - For women with advanced endometrial carcinoma, Adriamycin (doxorubicin) and Platinol (cisplatin) improves survival more than whole-abdominal radiation ...
SABCS: Dose-Dense Chemotherapy Called Safe and Effective Dec 12, 2005
MedPage Today, ...to be answered. The study drugs were Adriamycin (doxorubicin), Taxol (paclitaxel), and Cytoxan (cyclophosphamide). In the sequential ...
Ecopia Obtains Patent Protection on ECO-4601 from the USPTO Dec 7, 2005
CCNMatthews (Communiqués de presse), Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ...
Eyesight, toxin connection Dec 12, 2005
San Bernardino Sun, ...treatment of dystonias. Also doxorubicin injections are being used to specifically treat blepharospasm. No definitive conclusions ...
Hycamtin® receives positive opinion in Europe for treatment of ... Nov 28, 2005
Medical News Today (press release), The first Study (protocol 090) compared the safety and efficacy of HYCAMTIN to the triple combination cyclophosphomide, doxorubicin and vincristine (CAV) in ...
Biocompatible Polymer Vesicles Dec 6, 2005
Chemical & Engineering News The team also showed that the water-soluble anticancer drug doxorubicin can be encapsulated in the vesicles and released slowly over a period of several hours. ...
Early Use of Herceptin Cost-Effective if Survival Really Improves ... Dec 1, 2005
Cancerpage.com, Treatment costs were 45,000 euros (doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab) or 47,800 euros (docetaxel, carboplatin and ...
Accentia Biopharmaceuticals announces that follow-up data Dec 2, 2005
EurekAlert (press release), ...with follicular B-cell non-Hodgkin's lymphoma are being treated with BiovaxID immunotherapy following PACE [Prednisone, Doxorubicin, Cyclophosphamide, and ...
R-CHOP Improves Outcomes as Initial Therapy in Follicular Lymphoma Nov 28, 2005
Cancer Consultants (press release), Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves outcome ...
DPPE Added to Chemo Relieves Pain in Advanced Prostate Cancer Dec 2, 2005
Cancerpage.com, Reuters Health has previously reported results of a phase III trial in which DPPE increased survival when added to doxorubicin for treatment of breast cancer. ...
Conforma Therapeutics Names Thomas M. Estok as Chief Commercial ... Nov 29, 2005
Business Wire (press release), During his tenure at Schering-Plough, Mr. Estok led the oncology marketing efforts on multiple products including temozolomide, liposomal doxorubicin, and alpha ...
BioAlliance Pharma Files For EUR30M IPO On Euronext In Paris Nov 29, 2005
BioWorld Online (subscription), BioAlliance's third most advanced product is doxorubicin Transdrug, which is undergoing a Phase I/II clinical trial in Europe in the indication of primary ...
Neulasta® and Aranesp® Prevent Adverse Effects of Dose-Dense ... Nov 28, 2005
Cancer Consultants (press release), The women received a chemotherapy regimen consisting of doxorubicin and cyclophosphamide every two weeks for four cycles, followed by paclitaxel every two ...
Long-term remission after autologous peripheral blood stem cell ... Nov 24, 2005
Nature.com (subscription), She achieved a complete remission (CR) after five courses of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) therapy. ...
Neulasta® and Aranesp® Provide Effective Hematopoietic Support ... Nov 21, 2005
Cancer Consultants (press release), A total of 135 patients received 4 cycles of Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide) followed by 4 cycles of Taxol® (paclitaxel). ...
Rituxan® Plus CHOP Improves Outcomes of Patients with Follicular ... Nov 22, 2005
Cancer Consultants (press release), Researchers from Germany have reported that adding Rituxan (rituximab) to CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) improves outcomes of ...
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