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dihydrosphingosine
dihydrosphingosine
information and resources from the National Cancer Institute
dihydrosphingosine
A saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), dihydrosphingosine competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo.
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dihydrosphingosine
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