dacarbazine
information and resources from the National Cancer Institute
NCI Thesaurus | dacarbazine
A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. NCI Thesaurus | dacarbazine
A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.
DTIC-Dome Bayer May 27 1975
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news articles
Sciclone’s Zadaxin Granted Orphan Drug Designation for Malignant ... Mar 20, 2006
PharmaLive.com (press release), ZADAXIN currently is being investigated in combination with dacarbazine (DTIC) chemotherapy with and without low-dose interferon alpha in a large, multi ...
Multiferon(R) Melanoma Article Accepted for Publication in Leading ... Mar 27, 2006
Yahoo! News (press release) The article will report on the use of Multiferon® following dacarbazine (DTIC) in a clinical trial that demonstrated a statistically significant advantage ...
Temodar® and Thalomid® Effective for Metastatic Neuroendocrine ... Mar 21, 2006
Cancer Consultants (press release), ...response rates are low and some of the agents studied include 5-fluorouracil, BiCNU® (carmustine), CeeNU® (lomustine), doxorubicin, dacarbazine and Zanosar. ...
Zacks Analyst Blog Highlights: MedImmune, Inc., Mittal Steel, Cia ... Mar 28, 2006
Business Wire (press release), ...metastatic melanoma. Single therapy Vitaxin offered 0% response rate versus a 13% response rate for Vitaxin + DTIC (dacarbazine). Since ...
Genta Incorporated Announces Fourth Quarter and Year End 2005 ... Mar 10, 2006
PR Newswire (press release), Genta completed submission of its Marketing Authorization Application (MAA) for Genasense plus dacarbazine for treatment of patients with advanced melanoma. ...
Genta Receives Designation as a Small/Medium Enterprise by the ... Mar 16, 2006
PR Newswire (press release), SME designation.". The MAA proposes the use of Genasense plus dacarbazine for treatment of patients with advanced melanoma. Summary ...
FDA orphan status for SciClone skin cancer drug Mar 20, 2006
Pharmaceutical Business Review Zadaxin is currently being investigated in combination with dacarbazine (DTIC) chemotherapy with and without low-dose interferon alpha in a large, multi ...
Genta and Emisphere Technologies Enter into Exclusive Worldwide ... Mar 23, 2006
Yahoo! News (press release) Genta has also completed a Marketing Authorization Application to the European Medicines Agency (EMEA) for use of Genasense plus dacarbazine for treatment of ...
Genta Receives Designation as a Small/Medium Enterprise by the ... Mar 16, 2006
PR Newswire (press release), MAA, and we greatly appreciate the assistance accorded us with the SME designation." The MAA proposes the use of Genasense plus dacarbazine for treatment of ...
International Approvals: Alertec, Multiferon, Alvesco Feb 27, 2006
Medscape (subscription) ...for a natural human alpha-interferon injection, allowing its use for the adjuvant treatment of high-risk melanoma after excision and dacarbazine therapy; and ...
Genta Posts Q4 Loss On Lower Revenues - Update Mar 10, 2006
Trading Markets, In the same month, it submitted a Marketing Authorization Application to the European Medicines Agency for the use of Genasense plus dacarbazine as treatment ...
Neoadjuvant Sarcoma Chemotherapy Results in High Toxicity Levels Mar 1, 2006
Cancerpage.com, The patients received three cycles of neoadjuvant modified mesna, doxorubicin, ifosfamide and dacarbazine (MAID), interdigitated radiotherapy and following ...
Bilateral adrenal masses: phaeochromocytoma or melanoma? Feb 28, 2006
Journal of the Royal Society of Medicine Despite replacement steroids and a course of palliative dacarbazine chemotherapy, the patient died 9 months after first detection of the adrenal masses. ...
Genasense(R) New Drug Application Accepted for Review by FDA Mar 1, 2006
Yahoo! News (press release) Genta has also filed a Marketing Authorization Application to the European Medicines Agency (EMEA) for use of Genasense plus dacarbazine for treatment of ...
Neoadjuvant Chemotherapy and Radiotherapy Promising for Large Soft ... Mar 3, 2006
Cancer Consultants (press release), All were scheduled to receive neoadjuvant concomitant radiotherapy and chemotherapy with MAID (mesna, ifosfamide, doxorubicin and dacarbazine). ...
Viragen to Present Multiferon(R) European Strategy at BioSquare ... Feb 28, 2006
PR Newswire (press release), ...natural human alpha interferon) for the first- line adjuvant treatment of high-risk (Stages IIb-III) malignant melanoma following dacarbazine (DTIC) after ...
Randomized Trial Shows Ganite(R) Effective When Compared with a ... Mar 2, 2006
PR Newswire (press release), Genta has also submitted a Marketing Authorization Application to the European Medicines Agency (EMEA) for use of Genasense plus dacarbazine for treatment of ...
Patients with Unfavorable Risk Hodgkin’s Lymphoma May Not ... 21 Dec 2005
Cancer Consultants (press release), ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is the most commonly used chemotherapy regimen for Hodgkin’s lymphoma. ...
SciClone says drug misses trial targets, shares plunge Dec 14, 2005
Reuters Zadaxin was, however, found effective in the treatment of malignant melanoma when administered in combination with dacarbazine chemotherapy in a mid-stage trial ...
SciClone melanoma drug looks promising Dec 14, 2005
United Press International The companies are testing a new treatment, Zadaxin, in a large phase 2 trial that is evaluating the drug in combination with dacarbazine chemotherapy with and ...
Techs Fall on Apple's Downgrade Dec 14, 2005
123Jump.com, SciClone said it and Sigma-Tau SpA have found from interim results from a Phase 2 trial that Zadaxin with dacarbazine chemotherapy showed a dose-dependent ...
SciClone and Sigma-Tau Report Promising Interim Phase 2 Results in ... Dec 14, 2005
Market Wire (press release) ...announced promising interim results from a large phase 2 clinical trial evaluating ZADAXIN® (thymalfasin) in combination with dacarbazine (DTIC) chemotherapy ...
Viragen Holds Annual Stockholder Meeting: CEO Issues Progress ... Dec 15, 2005
PR Newswire (press release), ...to expand the approval for Multiferon(R) to include the first-line adjuvant treatment of high-risk malignant melanoma, following dacarbazine (DTIC) after ...
PharmaMar Reports Positive Phase II Results on Aplidin(R) in ... Dec 12, 2005
PR Newswire UK (press release), ...of other tumour types, including melanoma, solid tumours and Non-Hodgkin's Lymphoma, both as a single agent and in combination with dacarbazine (DTIC) and ...
Annual Meeting of the American Society of Hematology Highlights ... Dec 6, 2005
PR Newswire (press release), ...intention to submit a Marketing Authorization Application (MAA) to the European Medicines Agency (EMEA) for the use of Genasense plus dacarbazine in patients ...
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