cyclophosphamide
information and resources from the National Cancer Institute
cyclophosphamide
A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
Cytoxan Injection Bristol-Myers Squibb Nov 16 1959
Cytoxan Injection Bristol-Myers Squibb Apr 29 1987
Cytoxan Tablet Bristol-Myers Squibb Apr 29 1987
Cytoxan, Neosar Bristol-Myers Squibb Nov 16 1959
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news articles
Pentostatin, Cyclophosphamide, Rituxan® Active in Chronic ... Mar 10, 2006
Cancer Consultants (press release), Clinic recently conducted a clinical trial evaluating the treatment combination consisting of chemotherapy agents pentostatin and cyclophosphamide and the ...
ICE Plus CAV Intensification Promising for High Risk Ewing’s ... Mar 31, 2006
Cancer Consultants (press release), ...have reported that an induction regimen of ifosfamide, carboplatin and etoposide (ICE) followed by intensification with cyclophosphamide, doxorubicin, and ...
Genentech and Biogen File Rituxan with FDA for Non-Hodgkin's ... Mar 31, 2006
Cancerpage.com, In a joint statement, the companies said Rituxan would be used with CVP (cyclophosphamide, vincristine and prednisone) or CHOP (cyclophosphamide, doxorubicin ...
La Jolla Pharmaceutical Company Presents at National Autoimmune ... Mar 29, 2006
International News Service, ...to its primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide. ...
Supergen Announces Results from Combination Study in Cll Published ... Mar 14, 2006
PharmaLive.com (press release), NASDAQ:SUPG) announced today that an article entitled, "Pentostatin, Cyclophosphamide, and Rituximab Is an Active, Well-Tolerated Regimen for Patients With ...
TAXOTERE(R) Receives US FDA Approval For Use In Advanced Stomach ... Mar 23, 2006
Yahoo! News (press release) ...or metastatic breast cancer after failure of prior chemotherapy, * TAXOTERE® is approved in combination with doxorubicin and cyclophosphamide (TAC regimen ...
Taxotere®/Platinol®/Herceptin® Effective in Locally Advanced ... Mar 22, 2006
Cancer Consultants (press release), Herceptin followed by surgery, followed by subsequent chemotherapy including Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide), radiation therapy and ...
FDA Approvals: Aranesp, Taxotere, Leukine Mar 28, 2006
Medscape (subscription) ...of locally advanced or metastatic breast cancer after failure of prior chemotherapy, and for adjuvant use with doxorubicin and cyclophosphamide in the ...
Ziopharm presents preclinical kidney toxicity data on metabolite ... Mar 23, 2006
Therapeutics Daily (subscription) (press release), ZIO-201, the active metabolite of ifosfamide, may be less likely to kill normal kidney cells than the other metabolites of both cyclophosphamide and ifosfamide ...
FDA APPROVES TAXOTERE(R) FOR THE TREATMENT OF PATIENTS WITH ... Mar 24, 2006
PR Newswire (press release), Treatment-related acute myeloid leukemia (AML) has occurred in patients given anthracyclines and/or cyclophosphamide, including use with TAXOTERE(R) in ...
Adjuvant High-Dose Chemotherapy Improves Outcomes of HER2/neu ... Mar 7, 2006
Cancer Consultants (press release), ...have reported that patients with high-risk localized breast cancer receiving high-dose chemotherapy with Cytoxan® (cyclophosphamide), Thiplex® (thiotepa ...
Cell Therapeutics shows pixantrone data Mar 22, 2006
BusinessWeek ...the CHOP regimen. The CHOP regimen uses the drugs cyclophosphamide, vincristine, prednisone and doxorubicin. Cell Therapeutics replaced ...
Dr. Joseph Burchenal, 93; Chemotherapy Pioneer Mar 19, 2006
Los Angeles Times, Burchenal and Dr. Herbert F. Oettgen of Sloan-Kettering developed a regimen that included the anti-cancer drug cyclophosphamide and several others to combat ...
Dr. Joseph H. Burchenal, 93, Who Devised Cancer-Drug Therapy, Dies Mar 16, 2006
Haber Sa?l?k, F. Oettgen, an oncologist and immunologist at Sloan-Kettering, collaborated with Dr. Burchenal in testing several drugs, including cyclophosphamide, to combat ...
Immune system attacks body in lupus Mar 23, 2006
The Daily Athenaeum Interactive, ...include high dose prednisone (steroids), or other drugs that suppress the overactive immune system such as cyclophosphamide, methotrexate, hydroxychloroquine ...
US Study Fails to Confirm Benefits of Autologous Stem Cell ... Mar 14, 2006
Cancer Consultants (press release), This study called for VAD (vincristine, Adriamycin and dexamethasone) induction and cyclophosphamide/Neupogen® mobilization of peripheral blood stem cells in ...
Genasense(R) New Drug Application Accepted for Review by FDA Mar 1, 2006
Yahoo! News (press release) The NDA proposes the use of Genasense plus fludarabine and cyclophosphamide for the treatment of patients with relapsed or refractory chronic lymphocytic ...
Genta Incorporated Announces Fourth Quarter and Year End 2005 ... Mar 10, 2006
PR Newswire (press release), ...submitted a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for the use of Genasense plus fludarabine and cyclophosphamide as treatment ...
Pixantrone Combination Regimen Produces High Rates of Complete ... Mar 22, 2006
PR Newswire (press release), ...potentially curative bone marrow transplants." About the CHOP Regimen The CHOP chemotherapy regimen (a combination of cyclophosphamide, vincristine, prednisone ...
AIDS-related Lymphoma Outcome Improved By Combination Therapy Mar 2, 2006
Medical News Today (press release), They are treated with chemotherapy, often consisting of a multi-drug regimen using cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP). ...
Pixantrone Combination Regimen Produces High Rates of Complete ... Mar 22, 2006
PharmaLive.com (press release), The CHOP chemotherapy regimen (a combination of cyclophosphamide, vincristine, prednisone and doxorubicin) is the standard-of-care treatment for newly ...
CHOP Plus HAART Safe and Effective for AIDS-Related Lymphomas Mar 13, 2006
Cancer Consultants (press release), 2001. Patients were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in addition to concomitant HAART. ...
Committee for Medicinal Products for Human Use Post-authorisation ... Mar 24, 2006
PharmaLive.com (press release), Taxotere (docetaxel) in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with operable node- positive ...
Genta and Emisphere Technologies Enter into Exclusive Worldwide ... Mar 23, 2006
Yahoo! News (press release) ...has submitted a New Drug Application (NDA) to the US Food and Drug Administration for the use of Genasense plus fludarabine and cyclophosphamide for treatment ...
NCCN: Cancer Network Develops Guidelines for Breast Cancer in ... Mar 13, 2006
CNN During pregnancy, patients have usually been treated with combinations of Adriamycin (doxorubicin), Cytoxan (cyclophosphamide), and fluorouracil. ...
FDA accepts Genta's application Mar 1, 2006
MarketWatch Genasense would be used in combination with the chemotherapy drugs fludarabine and cyclophosphamide. Genta filed the application with the FDA in late December. ...
Today's Early Winners and Losers Mar 1, 2006
TheStreet.com The company wants to use Genasense, which has had a rocky history, along with fludarabine and cyclophosphamide for treating patients with relapsed or ...
FDA Approves Rituxan (Rituximab), the First Targeted B-Cell ... Mar 1, 2006
DG News In addition, Rituxan received FDA approval in February 2006 for the treatment of DLBCL in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and ...
FDA Approves Rituxan for Refractory Rheumatoid Arthritis Mar 1, 2006
MedPage Today, ...in the New England Journal of Medicine in 2004, a single course of two infusions of Rituxan, alone or in combination with either cyclophosphamide or continued ...
FDA to review Genta drug in leukemia indication Mar 2, 2006
Pharmaceutical Business Review The company is seeking approval for the use of Genasense plus fludarabine and cyclophosphamide for the treatment of patients with relapsed or refractory ...
Analysis:Pregnancy and breast cancer Mar 10, 2006
United Press International During pregnancy, patients have usually been treated with combinations of doxorubicin, cyclophosphamide and fluorouracil - potent anti-cancer drugs.
Q&A: Breast Cancer During Pregnancy Mar 6, 2006
CancerWise The treatment is called FAC chemotherapy (5-flurouracil, doxorubicin, and cyclophosphamide). The chemotherapy was given during the second and third trimesters. ...
Genta Posts Q4 Loss On Lower Revenues - Update Mar 10, 2006
Trading Markets, 2005, it submitted a New Drug Application to the US Food and Drug Administration for the use of Genasense plus fludarabine and cyclophosphamide as treatment ...
First Guidelines for Treatment of Breast Cancer During Pregnancy ... Mar 13, 2006
DG News ...offered. During pregnancy, patients have usually been treated with combinations of doxorubicin, cyclophosphamide and 5-fluorouracil. ...
High-Dose Therapy Does Not Improve Multiple Myeloma Outcome Mar 9, 2006
Cancerpage.com, ...received melphalan and total-body irradiation and allotransplantation or standard chemotherapy with vincristine, carmustine, cyclophosphamide, melphalan and ...
Genta leukemia drug accepted for review Mar 1, 2006
United Press International ...is seeking approval of the injectable treatment from the Food and Drug Administration for use with chemotherapy agents fludarabine and cyclophosphamide for the ...
Various Forms of Life in Antineutrophil Cytoplasmic Antibody ... Mar 6, 2006
Annals of Internal Medicine ...our previously cited data support the notion that relapses can be diminished with more prolonged therapy and that such therapy need not include cyclophosphamide ...
SuperGen Reports Results From Combination Study In CLL Published ... Mar 14, 2006
Trading Markets, Oncology showed higher response rates and similar or less toxicity using a three-drug combination therapy of pentostatin, cyclophosphamide and rituximab for ...
International Approvals: Rotarix, Hycamtin, Pulmicort HFA Mar 6, 2006
Medscape (subscription) Results of the first study showed topotecan to be similarly effective to a 3-drug regimen (cyclophosphamide, doxorubicin, and vincristine [CAV]) with respect ...
Cancer not stopping student Mar 9, 2006
Tiffin Advertiser Tribune, He's taken weekly doses of vincristine and dactinomycin, plus cyclophosphamide every third Friday when he stays overnight in Toledo. ...
Adjuvant Taxotere® and Herceptin® Effective for Breast Cancer ... Mar 6, 2006
Cancer Consultants (press release), ...have reported that Taxotere® (docetaxel) is superior to Navelbine® (vinorelbine) when given in addition to 5-FU, epirubicin and cyclophosphamide (FEC) for ...
Genentech, Biogen Idec Gain Approval Of Rituxan In RA Mar 1, 2006
BioWorld Online (subscription), ...line combination agent in diffuse large B-cell, CD20-positive, non-Hodgkin’s lymphoma in combination with CHOP (cyclophosphamide, doxorubicin, vincristine ...
High-Dose Chemotherapy Improves Outcomes of HER2/neu Negative ... Mar 13, 2006
Cancer Consultants (press release), ...cancer). They were treated with a standard chemotherapy regimen referred to as FEC (5-fluorouracil, epirubicin, cyclophosphamide). ...
Genta to have Genasense decision by fall Mar 1, 2006
BusinessWeek ...its marketing application for Genasense to treat chronic lymphocytic leukemia in conjunction with two chemotherapy drugs fludarabine and cyclophosphamide. ...
The antioxidant herb Feb 25, 2006
Malaysia Star, 8. Haque R, Bin-Hafeez B, Ahmad I, Parvez S, Pandey S, Raisuddin S. Protective effects of Emblica officinalis Gaertn. in cyclophosphamide-treated mice. ...
CHOP Plus HAART Improves Outcome of AIDS-Related Lymphoma Feb 28, 2006
Cancerpage.com, NEW YORK FEB 27, 2006 (Reuters Health) - In patients with AIDS-related lymphoma, combined treatment with cyclophosphamide, doxorubicin, vincristine, and ...
Simultaneous HIV therapy and chemotherapy for lymphoma effective ... Feb 28, 2006
Aidsmap, Acquired immune deficiency syndrome-related lymphoma: simultaneous treatment with combined cyclophosphamide, doxorubicin, vincristine and prednisone ...
PDL's Potent Pick-Me-Up Feb 27, 2006
BusinessWeek IV Busulfex is approved as a conditioning agent to be used in combination with cyclophosphamide prior to blood or marrow transplant in patients with chronic ...
Patients with Unfavorable Risk Hodgkin’s Lymphoma May Not ... 21 Dec 2005
Cancer Consultants (press release), BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone) is a more intensive regimen that has also been ...
Dose-Dense Chemotherapy Safe and Effective; Particularly for ... 21 Dec 2005
Cancer Consultants (press release), Patients received the study drugs Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide), either concurrently, or sequentially in ...
Herceptin, new breast cancer medication 21 Dec 2005
Auburn Citizen, In the trials, patients who were taking Herceptin with other chemotherapy drugs (anthracyclines and cyclophosphamide) experienced heart problems. ...
Taxotere/Cyclophosphamide Offers Greater Disease-Free Survival for ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- The combination of docetaxel (Taxotere) and cyclophosphamide should replace doxorubicin (Adriamycin)/cyclophosphamide ...
Dose Dense Doxorubicin-Docetaxel Combination Comparable to ... Dec 13, 2005
DG News SAN ANTONIO, TX -- December 13, 2005 -- The pre-operative sequential combination of doxorubicin plus cyclophosphamide administered over four cycles followed by ...
New Study Demonstrates Nonanthracycline Adjuvant Regimen TC ... Dec 11, 2005
PR Newswire (press release), 11 /PRNewswire/ -- The final analysis of an AC/TC adjuvant chemotherapy trial showed that TC (Docetaxel/Cyclophosphamide, 4 cycles) produced a superior disease ...
New Study Demonstrates Nonanthracycline Adjuvant Regimen TC ... Dec 12, 2005
PharmaLive.com (press release), HOUSTON, December 11, 2005 /PRNewswire/ -- The final analysis of an AC/TC adjuvant chemotherapy trial showed that TC (Docetaxel/Cyclophosphamide, 4 cycles ...
Breast Cancer Treatment Dec 16, 2005
Food Consumer, 90. Pritchard KI, Paterson AH, Fine S, et al.: Randomized trial of cyclophosphamide, methotrexate, and fluorouracil chemotherapy added to tamoxifen as adjuvant ...
Pilot Study Shows Abraxane Safe and Effective in Sequence with ... Dec 13, 2005
DG News In the study, treatment consisted of dose-dense doxorubicin and cyclophosphamide (AC) every 2 weeks over 4 cycles, followed by Abraxane 260 mg/m 2 every 2 ...
Rituxan® and CHOP for Elderly Patients with Diffuse Large B-Cell ... Dec 19, 2005
Cancer Consultants (press release), Researchers in Germany have reported that six cycles of Rituxan® (rituximab) and CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), given ...
Dose-Dense Chemotherapy Found More Effective than Standard ... Dec 13, 2005
DG News In one arm of the study patients received doxorubicin 60 mg/m 2 every 2 weeks over a 22-week period, cyclophosphamide over a 14 week period, and paclitaxel ...
Little Difference between Docetaxel and Paclitaxel in Treating ... Dec 14, 2005
DG News ...before released data show that there is virtually no difference in disease-free survival when a regimen comprising doxorubicin and cyclophosphamide is followed ...
Adjuvant Therapy with Taxotere® and Cytoxan® Improves Breast ... Dec 13, 2005
Cancer Consultants (press release), Compared to the standard chemotherapy combination of Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide), adjuvant therapy with Taxotere® (docetaxel ...
C-myc Gene Influences Response to Herceptin® Dec 14, 2005
Cancer Consultants (press release), The researchers evaluated patients in the NSABP B-31 clinical trial, which compared treatment with AC-T (doxorubicin,cyclophosphamide,paclitaxel) to treatment ...
New Treatment Regimen May Improve Mantle Cell Lymphoma: Presented ... Dec 14, 2005
DG News ...antibody with an attached radioactive substance (yttrium), along with standard chemotherapy for MCL including fludarabine, cyclophosphamide, and mitoxantrone ...
Adding Radioimmunotherapy To Chemotherapy Reduces Relapse Risk In ... Dec 17, 2005
Medical News Today (press release), ...blood stem cells were collected, after which they received a high dose of Zevalin followed by the chemotherapeutic drug cyclophosphamide and etoposide. ...
SUPG: Nipent Studies Presented at ASH Dec 9, 2005
PharmaLive.com (press release), A combination regimen of pentostatin, cyclophosphamide and rituximab (PCR) is suggested to have comparable activity to fludarabine, cyclophosphamide, and ...
Source: sanofi-aventis Dec 8, 2005
Yahoo! News (press release) A standard treatment of 4 cycles of doxorubicin and cyclophosphamide followed by TAXOTERE®-- for 4 cycles (AC --> T), * An experimental arm of the above ...
Taxane-Based Breast Cancer Treatment Cost-Effective Compared to 5 ... Dec 13, 2005
DG News December 13, 2005 -- Despite higher drug costs and more adverse effects, researchers say a combination of docetaxel, doxorubicin and cyclophosphamide (TAC) is ...
First Line Treatment with Herceptin Improves Outcomes in Early ... Dec 9, 2005
DG News ..."At 23 month median follow-up, doxorubicin plus cyclophosphamide and docetaxel and trastuzumab and the regimen of trastuzumab, carboplatin and docetaxel ...
Tandem High-Dose Chemotherapy Superior to Dose-Dense Chemotherapy ... Dec 5, 2005
Cancer Consultants (press release), All patients received 2 courses of chemotherapy with epirubicin and cyclophosphamide (EC) at 2 week intervals supported by Neupogen. ...
(PRN) US Oncology Research Network Presenting Numerous Studies at ... Dec 11, 2005
Houston Chronicle, Dr. Jones presented the final analysis of an AC/TC adjuvant chemotherapy trial showed that TC (Docetaxel/Cyclophosphamide, 4 cycles) produced a superior disease ...
Lupus nephritis, Mycophenolate Mofetil may be more effective in ... Dec 1, 2005
Xagena.it, ...inflammation Mycophenolate Mofetil ( CellCept ) may be more effective in inducing remission than standard regimen of intravenous Cyclophosphamide ( Cytoxan ). ...
The Pill Called Okay After All for Women With Stable Lupus Dec 14, 2005
MedPage Today, ...oral contraceptives could help to preserve ovarian function and reduce the likelihood of infertility from treatment with Cytoxan (cyclophosphamide), and they ...
Dose-Dense Chemotherapy Safe and Effective—Particularly for ... Dec 13, 2005
Cancer Consultants (press release), Patients were first randomly assigned to receive concurrent Adriamycin® (doxorubicin), Taxol® (paclitaxel), and Cytoxan® (cyclophosphamide) or concurrent ...
Taxotere® Vs. Taxol® in Adjuvant Treatment of Breast Cancer Dec 14, 2005
Cancer Consultants (press release), Taxotere® (docetaxel) and Taxol® (paclitaxel) produce similar outcomes when given after Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide) in the ...
Short Course of Herceptin® in Patients with Breast Cancer Dec 9, 2005
Cancer Consultants (press release), In breast cancer patients treated with docetaxel or vinorelbine followed by FEC (5-fluorouracil, epirubicin, cyclophosphamide), a nine-week course of Herceptin ...
cMyc Amplification Confers Increased Activity with the Addition of ... Dec 13, 2005
Cancer Consultants (press release), The researchers evaluated patients enrolled in the NSABP B-13 trial in which AC-T (doxorubicin, cyclophosphamide, paclitaxel) was compared with AC-TH ...
Metronomic Therapy Appears Useful in Advanced Breast Cancer ... Dec 8, 2005
DG News ...he said, noting that in a second arm of the randomized study, only 2 (9.5%) of 21 patients responded to metronomic doses of cyclophosphamide and methotrexate. ...
(PRN) - Telik's TELINTRA Demonstrates Positive, Clinically ... Dec 11, 2005
Bolsamania.com, ...[+]. (PRN) - New Study Demonstrates Nonanthracycline Adjuvant Regimen TC (Docetaxel and Cyclophosphamide) Is Superior to Standard AC (Doxorubicin ...
Non-Anthracycline Chemotherapy Regimen Plus Herceptin®: Effective ... Dec 13, 2005
Cancer Consultants (press release), Phase III Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed by Docetaxel (AC-T) with Doxorubicin and Cyclophosphamide Followed by Docetaxel ...
Pilot Clinical Study of Genasense(R) Plus Rituxan(R) and ... Dec 12, 2005
PR Newswire (press release), A randomized Phase 3 trial of 241 patients who received fludarabine plus cyclophosphamide (Flu/Cy) with or without Genasense showed that the addition of ...
Taxotere®/Cytoxan® Superior to Standard Adriamycin®/Cytoxan as ... Dec 14, 2005
Cancer Consultants (press release), ...from the US Oncology Research in Houston reported that the chemotherapy combination Taxotere (docetaxel) plus Cytoxan (cyclophosphamide) provides superior ...
ATLANTA -- Abstracts Presented at 2005 ASH Annual Meeting Reveal ... Dec 14, 2005
dBusinessNews Atlanta (press release), ASCT trials. The first was a phase I/II dose escalation trial of high-dose ZEVALIN plus cyclophosphamide and etoposide. The second ...
AnorMED announces 73 percent of cancer patients who failed prior ... Dec 12, 2005
PR Newswire (press release), Prior mobilization regimens included: 33 using G-CSF alone; 17 using cyclophosphamide (chemotherapy) plus G-CSF; 37 using cyclophosphamide plus G-CSF plus ...
Researchers study breast cancer therapy Dec 15, 2005
myDNA.com, It found that adjuvant chemotherapy with the drugs Taxotere (docetaxel) and Cytoxan (cyclophosphamide) improves disease-free survival rates by 33 percent over ...
La Jolla Pharmaceutical Data Published in Peer Reviewed Journals ... Dec 14, 2005
PR Newswire (press release), ...to its primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide. ...
Chemotherapy Consolidation with Zevalin(R) (90Y-Ibritumomab ... Dec 12, 2005
PR Newswire UK (press release), ...nodes or measurable masses on CT scans following treatment with Zevalin after fludarabine-based chemotherapy (fludarabine, cyclophosphamide and mitroxatone (FCM ...
Results of Investigator Initiated Trial of CellCept in Lupus ... Nov 25, 2005
Yahoo! News (press release) M. Ginzler's investigator initiated trial (IIT) comparing orally administered mycophenolate mofetil (CellCept®) to intravenous cyclophosphamide as induction ...
Worrying Too Much Dec 15, 2005
Monitor, Then there’s the cyclophosphamide, an agent so toxic to cells that it’s normally used for fighting cancer and could make it impossible for Abby to ever ...
Organ rejection drug may treat lupus side effect Dec 13, 2005
NorthJersey.com, They were randomly given monthly injections of the chemotherapy drug Cytoxan (cyclophosphamide) or daily oral doses of CellCept (micophenolate mofetil). ...
Zevalin Used in Abbreviated Chemotherapy Regimen Shows Efficacy ... Dec 16, 2005
DG News CHOP-R comprises a combination of rituximab (Mabthera(R)), cyclophosphamide, doxorubicin, (Adriamycin(R)), vincristine (Oncovin(R)) and prednisolone. ...
High-dose Chemotherapy Plus Growth Factor Helps in Locally ... Dec 2, 2005
MedPage Today, The high-dose regimen (201 patients) consisted of two cycles of epirubicin and cyclophosphamide followed by tandem epirubicin and cyclophosphamide plus ...
Interim Analysis of Phase III Study Shows TAXOTERE-Based Regimens ... Dec 8, 2005
PharmaLive.com (press release), ...or metastatic breast cancer after failure of prior chemotherapy, and it is also approved in combination with doxorubicin and cyclophosphamide (TAC regimen) for ...
Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast Cancer ... Dec 9, 2005
PR Newswire (press release), Pilot Study of Dose-Dense Doxorubicin plus Cyclophosphamide Followed by ABI-007 (ABRAXANE) in Patients with Early-Stage Breast Cancer Nicholas Robert, MD, US ...
Long-term remission after autologous peripheral blood stem cell ... Nov 24, 2005
Nature.com (subscription), She achieved a complete remission (CR) after five courses of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) therapy. ...
Drug helps treat kidney issues in lupus patients Nov 23, 2005
MSNBC ...saw their kidney problems go into complete remission after six months, compared with just 6 percent of those who received the older treatment, cyclophosphamide ...
(PRN) Positive ABRAXANE(R) Data in Early-Stage (Adjuvant) Breast ... Dec 9, 2005
Houston Chronicle, Preliminary results from a phase II trial showed that dose-dense therapy with doxorubicin (Adriamycin(R)) (A) plus cyclophosphamide (Cytoxan(R)) (C) followed ...
Dose-dense Chemotherapy For Early Breast Cancer Found Safe ... Dec 7, 2005
Science Daily (press release) ...of 1214 women with early-stage breast cancer were randomly assigned to receive six courses of 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) either ...
Genta study sees Genasense combo benefit Dec 12, 2005
BusinessWeek ...researchers found that the addition of Genasense to a treatment regimen using the anticancer drugs fludarabine and cyclophosphamide, significantly increased ...
Clinical Trial Supports Better Treatment For Lupus Patients ... Nov 24, 2005
Science Daily (press release) ...as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a ...
Research Published in The New England Journal of Medicine ... Nov 23, 2005
Yahoo! News (press release) ...clinical response and did not experience many of the severe side effects associated with the current standard-of-care, intravenous cyclophosphamide (IVC), a ...
Low-dose chemotherapy plus antiangiogenesis drug has activity in ... Dec 8, 2005
EurekAlert (press release), In the Dana-Farber study, the chemotherapy drugs cyclophosphamide and methotrexate were given in a metronomic regimen to 21 patients with advanced, metastatic ...
SABCS: Low-dose Frequent Chemotherapy Plus Avastin Shows Activity ... Dec 9, 2005
MedPage Today, By itself, however, the so-called metronomic therapy with Cytoxan (cyclophosphamide) and methotrexate was ineffective, reported Harold Burstein, MD, Ph.D., of ...
Study: Drug Shows Promise In Lupus Patients Nov 23, 2005
WBAL Channel.com, The current standard of care is intravenous cyclophosphamide, a form of chemotherapy that has been used to treat patients with lupus kidney disease since the ...
Low-Dose Chemotherapy Plus Antiangiogenesis Slows Advanced Cancer Dec 8, 2005
Ivanhoe, In the new study, a group of patients received the chemotherapy drugs cyclophosphamide and methotrexate in low, frequent doses referred to as metronomic, as a ...
Herceptin OK as upfront cancer drug Dec 9, 2005
Monsters and Critics.com, In Slamon`s study, patients were treated with three different regimens: One contained Adriamycin, cyclophosphamide and docetaxel (Taxotere); the same ...
Rituximab maintenance therapy dramatically improves survival in ... Dec 13, 2005
RxPG NEWS, ...of Cancer) trial, 465 patients with relapsed and refractory indolent NHL were randomised to receive either 3-weekly cyclophosphamide, doxorubicin, vincristine ...
Ritalin Conjugate Used to Treat "Chemo-Brain" in Breast Cancer ... Dec 13, 2005
DG News The most commonly used regimens were cyclophosphamide, doxorubicin, paclitaxel, 5-fluorouracil, methotrexate, docetaxel and carboplatin. ...
Benefit of Dose-Dense Chemotherapy for Early Breast Cancer Still ... Dec 7, 2005
Cancer Consultants (press release), Women were randomly assigned to receive 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) every three weeks or every two weeks, for a total of six cycles. ...
SABCS: Taxotere-Cytoxan Combo Shows Survival Advantage in Breast ... Dec 12, 2005
MedPage Today, 12 - Adjuvant chemotherapy with Taxotere (docetaxel) and Cytoxan (cyclophosphamide) delivers 33% better disease-free survival than the standard regimen of ...
VELCADE(R) (bortezomib) for Injection Continues to Show Impressive ... Dec 12, 2005
PR Newswire (press release), ...with CHOP Plus Rituximab (abstract #491) Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and ...
SABCS: No Differences Found In Taxane Treatment Results Dec 9, 2005
MedPage Today, ...disease. All patients received four cycles of Adriamycin (doxorubicin) and Cytoxan (cyclophosphamide) before the taxane therapy. ...
VELCADE (bortezomib) for Injection Continues to Show Impressive ... Dec 13, 2005
PharmaLive.com (press release), Results from a phase I/II study of VELCADE in combination with standard cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) plus rituximab for the ...
Long-Term Safety of Dose-Dense Adjuvant Chemotherapy for Breast ... Dec 8, 2005
Cancer Consultants (press release), Oncologico Nord Ovest-Mammella Inter Gruppo (GONO-MIG) has reported that a dose-dense regimen of fluorouracil, epirubicin, and cyclophosphamide (FEC) given ...
Maintenance therapy with RITUXAN(R) dramatically improves survival Dec 12, 2005
CNW Telbec (Communiqués de presse), In the trial, 465 patients with relapsed and refractory indolent NHL were randomised to receive either three- weekly cyclophosphamide, doxorubicin, vincristine ...
Treatment of Breast Cancer with Herceptin for Nine Weeks Dec 10, 2005
MedIndia, The women included in the study received docetaxel or vinorelbine and then FEC (5-fluorouracil, epirubicin, cyclophosphamide).Those whose HER-2 protein were ...
Ascenta AT-101 Data Presented at the American Society of ... Dec 12, 2005
PharmaLive.com (press release), Their data demonstrated significant improvement in therapeutic efficacy when AT-101 was added to a regimen of cyclophosphamide and rituximab versus treatment ...
SABCS: Shorter Chemotherapy Regimen Plus Taxol Reduces Breast ... Dec 12, 2005
MedPage Today, ...late 1990s, used a regimen commonly used in Europe -- six cycles of 5-fluorouracil, Ellence (epirubicin), and Cytoxan (and cyclophosphamide), often referred to ...
SABCS: Dose-Dense Chemotherapy Called Safe and Effective Dec 12, 2005
MedPage Today, ...to be answered. The study drugs were Adriamycin (doxorubicin), Taxol (paclitaxel), and Cytoxan (cyclophosphamide). In the sequential ...
Annual Meeting of the American Society of Hematology Highlights ... Dec 6, 2005
PR Newswire (press release), ...has initiated a "rolling" New Drug Application to the Food and Drug Administration for the use of Genasense plus fludarabine and cyclophosphamide in patients ...
Phase II Clinical Results Indicate That MyVax(R) Personalized ... Dec 12, 2005
PR Newswire (press release), ...or circumstances after the date hereof. (1) Chemotherapy regimen containing cyclophosphamide, adriamycin, vincristine, prednisone.
DNA Structure May Signal Prostate Cancer Dec 12, 2005
PR Newswire (press release), Encouragingly, the researchers were able to virtually eliminate this phenotype through intervention with a drug (cyclophosphamide) that also substantially ...
New Data Demonstrate ZEVALIN(R) Radioimmunotherapy May Play ... Dec 13, 2005
Finanzen.net, ZEVALINASCT trials. The first was a phase I/II dose escalation trial ofhigh-dose ZEVALIN plus cyclophosphamide and etoposide. The ...
Rituxan® Plus CHOP Improves Outcomes of Patients with Follicular ... Nov 22, 2005
Cancer Consultants (press release), Researchers from Germany have reported that adding Rituxan (rituximab) to CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) improves outcomes of ... |
