clodronate

clodronate information and resources from the National Cancer Institute

clodronate

A nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate disodium binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. clodronate

A nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate disodium binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain.

news articles



Clodronate® in Early Breast Cancer May Reduce Risk of Developing ... Mar 21, 2006
Cancer Consultants (press release), Bisphosphonates, such as Clodronate, have been beneficial in patients with cancer that has already spread to the bone and have effectively reduced fractures ...

New Study Shows Reduction in Bone Metastases for Patients Taking ... Mar 26, 2006
PR Newswire UK (press release), According to recent trial findings, Bonefos(R) (oral clodronate) plus standard adjuvant therapy in primary breast cancer is associated with both reduced bone ...

(PRN) - Innovative Technologies to Promote Enhanced Productivity ... Mar 26, 2006
Bolsamania.com, China ... [+. PRN) - New Study Shows Reduction in Bone Metastases for Patients Taking Oral Clodronate (BONEFOS(R)) ... PRN ...

Patients with Breast Cancer Bone Metastasis Failing Clodronate or ... Dec 16, 2005
Cancer Consultants (press release), ...significantly improved pain control in women with progressive bone metastasis from breast cancer who had progression while receiving clodronate or pamidronate. ...

Switching Bisphosphonates Improves Pain Control in Breast Cancer ... Dec 14, 2005
Cancer Consultants (press release), The women were originally taking the bisphosphonate drugs clodronate or pamidronate. They were switched to Zometa® (zoledronic acid). ...


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