calcitriol
information and resources from the National Cancer Institute
NCI Thesaurus | calcitriol
A synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Calcitriol regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth. A calcitriol receptor-binding protein appears to exist in the mucosa of human intestine. Calcitriol also induces cell cycle arrest at G0/G1 phase of the cell cycle, cell differentiation, and apoptosis, resulting in inhibition of proliferation of some tumor cell types. This agent may be chemopreventive for colon and prostate cancers. NCI Thesaurus | calcitriol
A synthetic physiologically-active analog of vitamin D, specifically the vitamin D3 form. Calcitriol regulates calcium in vivo by promoting absorption in the intestine, reabsorption in the kidneys, and, along with parathyroid hormone, regulation of bone growth. A calcitriol receptor-binding protein appears to exist in the mucosa of human intestine. Calcitriol also induces cell cycle arrest at G0/G1 phase of the cell cycle, cell differentiation, and apoptosis, resulting in inhibition of proliferation of some tumor cell types. This agent may be chemopreventive for colon and prostate cancers.
|
|
|
|
news articles
Treatment “Holidays� Effective in Hormone-Refractory Prostate ... Mar 1, 2006
Cancer Consultants (press release), ...of 45 patients involved in a larger clinical trial referred to as the ASCENT trial in which treatment with Taxotere® (docetaxel) plus Calcitriol (high-dose ...
ASCO Prostate: Intermittent Chemotherapy Controls Androgen ... Feb 28, 2006
MedPage Today, ...who participated in the phase III randomized ASCENT trial, which compared Taxotere (docetaxel) plus a high-dose vitamin D supplement (Calcitriol) to Taxotere ...
Calcitriol and QW-1624-F2-2 are promising for prevention of ... Nov 20, 2005
Xagena.it, Research's 4th annual Frontiers in Cancer Prevention Research meeting in Baltimore, has found that the active metabolite of vitamin D, Calcitriol, and other ...
Sapphire Therapeutics, Inc.'s Oral Ghrelin Mimetic Shows Potential ... Dec 15, 2005
Genetic Engineering News, The second drug, RC-8800, is a small molecule that acts on the vitamin D (calcitriol) metabolic pathway, being developed as a treatment for various cancers ...
Vitamin D May Help Treat Some Asthma Dec 8, 2005
WebMD That limits their treatment options. The form of vitamin D used in this study was calcitriol, or vitamin D-3. It's the form of vitamin D that the body uses. ...
Flip The Switch: Your Year To Get Slim Dec 12, 2005
KIROtv.com, ..."A high-calcium diet suppresses calcitriol, a hormone that signals fat cells to make more fat -- and burn less of it," explains Michael Zemel, Ph.D., director ...
FAMILY DOCTOR: LIchen sclerosis affects sexual function Dec 9, 2005
Canton Repository (subscription), New treatments are under investigation, one of which is calcitriol (a chemical related to vitamin D). Another is the use of pimecrolimus cream. ...
|
|
