bleomycin
information and resources from the National Cancer Institute
NCI Thesaurus | bleomycin
A mixture of glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. NCI Thesaurus | bleomycin
A mixture of glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.
Blenoxane Bristol-Myers Squibb Jul 31 1973
Blenoxane
Sclerosing agent for the treatment of malignant pleural effusion (MPE) and prevention of recurrent pleural effusions.
Bristol-Myers Squibb Feb 20 1996
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news articles
Thrombin-Activatable Fibrinolysis Inhibitor Deficiency Attenuates ... Mar 24, 2006
Am J Pathology (subscription) Therefore, we compared bleomycin-induced lung fibrosis in TAFI-deficient, heterozygous, and wild-type mice. The animals were sacrificed ...
Ecopia Presents Data Highlighting the Potential of Decipher'R' ... Mar 29, 2006
CCNMatthews (press release), The source is soil-dwelling microorganisms that have produced several potent anticancer agents such as doxorubicin, bleomycin and mitomycin. ...
Matrix Metalloproteinase Inhibitor Effective for Kaposi’s ... Mar 22, 2006
Cancer Consultants (press release), AIDS-related Kaposi’s sarcoma are initially treated with Doxil (liposomal doxorubicin) or combination chemotherapy with doxorubicin, bleomycin and vincristine ...
Alveolar fluid transport: a changing paradigm Mar 10, 2006
AJP-Lung Physiology ...and Matthay MA. Upregulation of alveolar epithelial fluid transport after subacute lung injury in rats from bleomycin. Am J Physiol ...
Patients with Unfavorable Risk Hodgkin’s Lymphoma May Not ... 21 Dec 2005
Cancer Consultants (press release), ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is the most commonly used chemotherapy regimen for Hodgkin’s lymphoma. ...
Benefits of Inovio's Selective Electrochemical Tumor Ablation ... Nov 20, 2005
Medical News Today (press release), ...today that the European Journal of Surgical Oncology published an article, entitled "The role of intratumour therapy with electroporation and bleomycin in the ...
Intensive Chemotherapy Regimen Shows Promise for Germ Cell Tumors Dec 5, 2005
Cancer Consultants (press release), This regimen consisted of cycles of cisplatin, vincristine, bleomycin, and carboplatin, followed by one cycle of vincristin and bleomycin and three cycles of ...
Role of Eotaxin-1 (CCL11) and CC Chemokine Receptor 3 (CCR3) in ... Dec 9, 2005
Am J Pathology (subscription) The present study examined the pulmonary expression of CCL11 and CCR3 during bleomycin (blm)-induced lung injury and determined their importance in the ...
PhotoCure ASA - PCI technology enhances effect of anti-cancer drug Dec 5, 2005
Biotech Intelligence (press release), ...journal Clinical Cancer Research, it is now demonstrated that PCI can significantly improve the curative effect of the anti-cancer drug bleomycin in animal ...
Journal of the American Podiatric Medical Association Nov 29, 2005
Journal of the American Podiatric Medical Association 73% of cases. Agents such as vinblastine, vincristine, and bleomycin are prescribed because of their limited toxicity. 3. A 73-year ...
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