benzoylphenylurea

benzoylphenylurea information and resources from the National Cancer Institute

NCI Thesaurus | benzoylphenylurea

A low molecular weight agent with antineoplastic activity. Benzoylphenylurea binds to the colchicine binding site on tubulin, thereby blocking tubulin polymerization and disrupting mitotic function. This agent also inhibits DNA polymerase, and has been shown to arrest leukemia cells in the G1-S transition phase of the cell cycle.NCI Thesaurus | benzoylphenylurea

A low molecular weight agent with antineoplastic activity. Benzoylphenylurea binds to the colchicine binding site on tubulin, thereby blocking tubulin polymerization and disrupting mitotic function. This agent also inhibits DNA polymerase, and has been shown to arrest leukemia cells in the G1-S transition phase of the cell cycle.



news articles



Recycled Or Revamped Therapeutics Find Novel Anti-cancer ... Nov 20, 2005
Science Daily (press release) According to their results, analogs for the would-be insecticide benzoylphenylurea (BPU), and analogs with improved activity under clinical development at ...

Recycled Or Revamped Therapeutics Find Novel Anti-cancer ... Nov 20, 2005
Science Daily (press release) According to their results, analogs for the would-be insecticide benzoylphenylurea (BPU), and analogs with improved activity under clinical development at ...


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