atrasentan

atrasentan information and resources from the National Cancer Institute

atrasentan

An orally available pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, thereby inhibiting tumor cell proliferation and tumor-associated angiogenesis. atrasentan

An orally available pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, thereby inhibiting tumor cell proliferation and tumor-associated angiogenesis.

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