anti-CD3 x anti-HER-2-neu bispecific monoclonal antibody

anti-CD3 x anti-HER-2-neu bispecific monoclonal antibody information and resources from the National Cancer Institute

NCI Thesaurus | anti-CD3 x anti-HER-2-neu bispecific monoclonal antibody

A murine monoclonal antibody with two antigen-recognition sites: one for CD3, an antigen expressed on mature T cells, and one for HER-2-neu, a tumor-associated antigen that promotes tumor growth. This agent attaches to CD3-expressing T cells and HER-2-neu-expressing tumor cells, selectively cross-linking tumor and immunologic cells which results in the recruitment of cytotoxic T cells to the T cell/tumor cell aggregate. NCI Thesaurus | anti-CD3 x anti-HER-2-neu bispecific monoclonal antibody

A murine monoclonal antibody with two antigen-recognition sites: one for CD3, an antigen expressed on mature T cells, and one for HER-2-neu, a tumor-associated antigen that promotes tumor growth. This agent attaches to CD3-expressing T cells and HER-2-neu-expressing tumor cells, selectively cross-linking tumor and immunologic cells which results in the recruitment of cytotoxic T cells to the T cell/tumor cell aggregate.

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