allopurinol

allopurinol information and resources from the National Cancer Institute

NCI Thesaurus | allopurinol

A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies. NCI Thesaurus | allopurinol

A structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies.

Zyloprim

Patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who cannot tolerate oral therapy.

GlaxoSmithKline May 17 1996



news articles



I was a middle-aged guinea pig Mar 31, 2006
Fort Wayne News Sentinel, ...held my pills: A red capsule, one a day. Its canister was labeled allopurinol, a prescription drug for chronic gout. A white capsule ...

Clinical trials and studies Mar 26, 2006
Ann Arbor News, ...mild to moderate neuropathy. The three drugs are nicotinamide, allopurinol and alpha-lipoic acid. Patients interested in enrolling ...

Nabi Biopharmaceuticals Announces Completion of Outside Advisory ... Mar 21, 2006
PR Newswire (press release), ...has three products on the market today: PhosLo(R) (calcium acetate), Nabi-HB(R) [Hepatitis B Immune Globulin (Human)], and Aloprim(TM) (allopurinol sodium) for ...

Nabi Biopharmaceuticals Announces US Fast Track Designation for ... Mar 10, 2006
PharmaLive.com (press release), ...has three products on the market today: PhosLo® (calcium acetate), Nabi-HB® [Hepatitis B Immune Globulin (Human)], and Aloprim™ (allopurinol sodium) for ...

Stones in the kidneys Feb 25, 2006
Malaysia Star, There are some medications to prevent formation of calcium and uric acid stones, such as allopurinol, which decreases uric acid crystal formation and certain ...

Nabi Biopharmaceuticals Updates Progress of its Gram-Positive ... 21 Dec 2005
PR Newswire (press release), ...three products on the market today: PhosLo(R) (calcium acetate), Nabi-HB(R) [Hepatitis B Immune Globulin (Human)], and Aloprim(TM) [Allopurinol sodium (for ...

New Gout Drug Does Well in Trial Dec 7, 2005
Forbes Patients who got febuxostat had lower levels of serum uric acid than those getting allopurinol, the standard medication for the painful condition, according to ...

Clinical Trials of New Drug Febuxostat Show Promise in Gout ... Dec 8, 2005
MedIndia, A new drug called febuxostat has been found to reduce plasma levels of uric acid more effectively in Gout than the currently used drug allopurinol. ...

Febuxostat Lowers Urate More Than Aloprim Dec 7, 2005
MedPage Today, ...drug febuxostat reduced serum urate levels significantly compared with the widely prescribed gout medication, Aloprim (allopurinol), researchers here reported. ...

New drugs effective against gout, colitis Dec 7, 2005
MSNBC The gout study involved about 760 patients and compared febuxostat with allopurinol, both of which remove excess urate from the blood. ...

Studies: Drugs Help Against Gout, Colitis Dec 10, 2005
Brocktown News, ...the end. Still, he said febuxostat will be helpful to the many patients who cannot take allopurinol or have weak kidneys. Gout, a ...

Report urges fixing system to ID the dead in disasters Nov 20, 2005
Indianapolis Star, A new drug called febuxostat may give better relief for those suffering from gout than allopurinol -- the current standard gout treatment -- researchers report ...

How the test is performed: Dec 5, 2005
About - News & Issues, Drugs that can decrease uric acid measurements include allopurinol, high-dose aspirin, azathioprine, clofibrate, corticosteroids, estrogens, glucose infusion ...

Rescuing Damaged Nerves Nov 22, 2005
WOWT, ...for diabetic neuropathy. Antioxidants used in the study include alpha lipoic acid, nicotinamide and allopurinol. Type one patients ...

Complications of Diabetes Nov 18, 2005
WSOCtv.com, The researchers are currently looking at three different antioxidants: alpha-lipoic, nicotinamide (vitamin B3) and allopurinol. ...


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