|
alanosine
alanosine
information and resources from the National Cancer Institute
alanosine
An amino acid analog derived from Streptomyces alanosinicus, a purine antagonist, and an adenylosuccinate synthetase inhibitor with antineoplastic properties. L-alanosine deprives MTAP-deficient (salvage pathway) tumor cells of de novo synthesized adenosine and is probably responsible for diminished DNA synthesis. The clinical use of L-alanosine may be narrow due to its toxicity profile. alanosine
An amino acid analog derived from Streptomyces alanosinicus, a purine antagonist, and an adenylosuccinate synthetase inhibitor with antineoplastic properties. L-alanosine deprives MTAP-deficient (salvage pathway) tumor cells of de novo synthesized adenosine and is probably responsible for diminished DNA synthesis. The clinical use of L-alanosine may be narrow due to its toxicity profile.
|
|
|
|
|
|
alanosine
-->
|
