adenovirus

adenovirus information and resources from the National Cancer Institute

NCI Thesaurus | adenovirus

One of a number of genetically-engineered adenoviruses designed to insert a gene of interest into a eukaryotic cell where the gene of interest is subsequently expressed. Unlike most other vectors, adenovirus vectors have the ability to infect post-mitotic cells. Thus, these agents are especially useful for gene transfer into neuronal cells. NCI Thesaurus | adenovirus

One of a number of genetically-engineered adenoviruses designed to insert a gene of interest into a eukaryotic cell where the gene of interest is subsequently expressed. Unlike most other vectors, adenovirus vectors have the ability to infect post-mitotic cells. Thus, these agents are especially useful for gene transfer into neuronal cells.



news articles



Adenovirus-alphavirus hybrid vector increases liver cancer ... Mar 30, 2006
Therapeutics Daily (subscription) (press release), 2006 MAR 30 - (NewsRx.com) -- According to recent research from Spain published in the journal Cancer Research, adenovirus-alphavirus hybrid vector increases ...

Researchers' findings advance HIV/AIDS vaccines research Mar 30, 2006
Therapeutics Daily (subscription) (press release), 1: Cytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA ...

Researchers' findings advance vaccines vector research Mar 9, 2006
TMCnet Study 1: Scientists examine the osmolality effect of two different serum-free media upon human 293 cell growth and adenovirus production in a recent issue of ...

Studies describe new findings in vaccines vector research Mar 9, 2006
TMCnet Study 1: Membrane-based technology reduces the time needed for the purification of adenovirus and adeno-associated virus. "Adenovirus ...

Contagious Obesity Mar 28, 2006
ScienCentral News, He noticed that people who had been exposed to a chicken adenovirus called SMAM-1 were consistently fatter than those who had had no exposure. ...

Experts Publish "State of the Science" Review of Genetic Medicine Mar 30, 2006
Newswise (press release) ...piggybacked genes. "Trouble is, host immune responses have limited the expression of adenovirus-delivered genes," Dr. O'Connor explains. So ...

Vaccines against Avian Influenza — A Race against Time Mar 29, 2006
New England Journal of Medicine (subscription), Other approaches to vaccine development involve DNA, adenovirus vectors, 13 and cell-culture manufacturing techniques to increase the speed and capacity of ...

Wave Bioreactor(R) Used In New Vaccine Production Facility Mar 28, 2006
PR Newswire (press release), ...the Wave Bioreactor(R) are in use worldwide, utilizing a wide variety of cells including CHO, NS0, hybridomas, HEK293, insect/baculovirus, adenovirus, T-cells ...

New Ideas Fuel Next Generation Gene Therapy Research Mar 7, 2006
eMaxHealth.com, It uses an adenovirus, the microbe that causes the common cold, as a "vector" - a sort of taxicab - that carries genetic material directly into cancer cells. ...

Three Cases of Dog Flu Confirmed Mar 25, 2006
YubaNet, ...influenza virus A, this PCR test also is used to detect other infectious diseases in dogs, including Bordetella bronchiseptica, distemper, adenovirus type 2 ...

Obesity Virus Mar 28, 2006
KEYT, A nutrition researcher infected chickens with different strains of the adenovirus, then compared their body fat with uninfected birds on the same diet. ...

Adenoviral vectors encoding TNF-a and FASL induce apoptosis of ... Mar 24, 2006
Journal of Endocrinology The infection of GH3 cells with adenovirus encoding TNF-a or FasL increased the percentages of hypodiploid and TUNEL positive cells. ...

Risks prompt new look at vaccination schedules Mar 24, 2006
Atlanta Journal Constitution (subscription), Hospital Association, which earlier this month released guidelines saying most dogs should receive core vaccinations — distemper, adenovirus, parvovirus and ...

Weight gain may be linked to Ad-3 virus Mar 17, 2006
Monsters and Critics.com, Atkinson research has shown that chickens, mice and marmosets become fatter after becoming infected with Ad-36, a human adenovirus that usually causes colds ...

Fat Virus, Ad-36 Blamed For Obesity Epidemic In Australians Mar 17, 2006
MedIndia, Ad-36, belongs to a class of viruses referred to as adenovirus. The virus is known to be associated with eye infections, diarrhea and common cold, in humans. ...

Research Suggest Virus Could Be Making People Fat Mar 20, 2006
CBS4Boston, ...contagious. Dr. Nikhil Dhurandhar discovered a human virus called adenovirus-36 made animals gain weight – a lot of weight. “We ...

Loose dog brought to animal shelter; owner sought Mar 17, 2006
The Eureka Reporter, ...the dog being placed in a hold kennel, it is given a seven-way vaccine for parvo, distemper, perainfluenza, Bordetella, the Corona virus and Adenovirus Type 2. ...

Separase: a universal trigger for sister chromatid disjunction but ... Mar 13, 2006
Journal of Cell Biology Abbreviations used in this paper: AdCre, adenovirus expressing Cre recombinase; AdGFP, adenovirus expressing GFP; APC/C, anaphase promoting complex or cyclosome ...

Biotechs wage genetic war on blindness Mar 17, 2006
Business Gazette, The vector used by GenVec is a disarmed version of an adenovirus, a family of viruses that in virulent forms cause a number of human maladies from eye ...

Advexin® Promising for Inoperable, Refractory Esophageal Cancer Mar 20, 2006
Cancer Consultants (press release), To produce Advexin, the p53 gene is inserted into a common virus (adenovirus) that has been rendered unable to produce illness in humans. ...

Gene therapy: Solving delivery problems Mar 7, 2006
Scripps Howard News Service, ...associated virus. Adeno-associated virus is a parasite that lives off adenovirus, the bug that causes colds and sore throats. "There ...

'Jumping Genes': New Target For Body's Innate Immune Protection ... Mar 9, 2006
Science Daily (press release) Landau. The tiny Adeno-associated virus depends on the help of the larger Adenovirus to multiply and does no harm in humans. "We ...

Avian Flu Researchers Make Strides Mar 7, 2006
Journal of American Medical Association (subscription), Various research teams are also working to develop a protective vaccine, and two groups recently found that adenovirus-based immunization strategies may have ...

New findings in the area of vector development detailed Mar 9, 2006
TMCnet Keywords: Ibaraki, Japan, Vector Development, Vaccine Vector, DNA Vaccine, Adenovirus Vector, Vaccine Development, Immunology, Immunotherapy, Proteomics ...

Cure for red eye Mar 1, 2006
Solomon Star, Epidemic keratoconjunctivitis is caused by a virus called adenovirus. It occurs invariably yearly or every two years in most populations in its epidemic form. ...

Alveolar fluid transport: a changing paradigm Mar 10, 2006
AJP-Lung Physiology Adenovirus-mediated transfer of an Na + /K + -ATPase 1 subunit gene improves alveolar fluid clearance and survival in hyperoxic rats. ...

Couple creates Web site for families facing aplastic anemia Feb 26, 2006
Beckley Register-Herald (subscription), ...short-lived. Less than a month later, Stephanie developed another virus, Adenovirus, which ended her life in May 2004. They found ...

Introgen Reports Advances in the Development of Oncolytic Viruses ... 21 Dec 2005
PharmaLive.com (press release), This portfolio includes a series of replication competent adenovirus vectors that over-express an adenoviral gene (ADP gene), a gene that causes rapid ...

Gene-Coated Stents May Boost Healing Dec 19, 2005
Forbes ...thick. The compound holds and gradually releases adenovirus particles (the gene vector), which then deliver the therapeutic genes. ...

Cidofovir an Option for Viral Infections in Pediatric Bone Marrow ... Dec 15, 2005
Cancerpage.com, NEW YORK DEC 14, 2005 (Reuters Health) - Results of a retrospective study support the efficacy of the antiviral cidofovir for adenovirus infections in ...

Tier doctors develop test for 'pink eye' Dec 14, 2005
Press & Sun-Bulletin, Dr. Jose Sambursky and his sons, Dr. Dan Sambursky and Dr. Rob Sambursky, created the Adenovirus Detector, which was recently cleared for use by the US Food ...

NYU med school testing HIV vaccine in experiment Dec 7, 2005
Daily Colonial, To make the vaccine, scientists combined a weakened version of the adenovirus, which causes the common cold, with lab-generated copies of genes from the outer ...

Transgene releases positive Phase I/II data of TG1042 (Ad-IFNg) ... Dec 11, 2005
Canada NewsWire (press release), About TG1042: ---- TG1042 uses Transgene's adenovirus vector carrying the human interferon gamma gene. About the presentation ...

Transgene Releases Positive Phase I/II Data of TG1042 (Ad-IFNg) ... Dec 11, 2005
Biotech Intelligence (press release), TG1042 uses Transgene's adenovirus vector carrying the human interferon gamma gene. The poster presentation is entitled "Adenovirus ...

Purdue researchers investigate alternate ways to protect humans ... Dec 8, 2005
Newstarget.com, Purdue molecular virologist Suresh Mittal and his colleagues are researching the use of a harmless adenovirus as a means of transmitting vaccine that will ...

International Approvals: Procoralan, H101, AP2573 Nov 21, 2005
Medscape (subscription) ...rhythm who have a contraindication or intolerance to beta-blockers; the Chinese State Food and Drug Administration has approved an oncolytic adenovirus for use ...

Cell Genesys San Diego Manufacturing Operation Acquired by Genzyme Nov 22, 2005
Yahoo! News (press release) ...new facilities to support its ongoing research and clinical trials, and to broaden the company's manufacturing capabilities related to both Adenovirus and Adeno ...

Drug firm to adapt measles shot to fight HIV Nov 28, 2005
MSNBC ...signed a collaboration with the International AIDS Vaccine Initiative to develop a vaccine using an adapted chimpanzee virus, known as an adenovirus, to carry ...

Past yields few clues for predicting flu Nov 20, 2005
USA Today Suresh Mittal looks over a cell infected with adenovirus carrying a bird flu gene in his research lab at Purdue University in West Lafayette, Ind. ...

US think tank details steps to contain bird flu Nov 20, 2005
USA Today Suresh Mittal examines a cell infected with adenovirus carrying a bird flu gene at Purdue University in West Lafayette, Ind. By Jeff Haynes, AFP/Getty Images. ...

Report id’s medico-ethical issues restrict gene therapy growth Nov 25, 2005
In-PharmaTechnologist.com, ...world approved for marketing. The treatment consists of an adenovirus designed to insert a gene called p53. This gene codes for ...

Wyeth awarded $32 M for HIV vaccine Dec 1, 2005
Science Daily (press release) ...but I think it is safe to say the field is increasingly excited about a number of candidates using an adenovirus vaccine vector," including Merck's, Warren said ...

Jefferson Scientists Uncover More Evidence For Protein's Role In ... Nov 28, 2005
Science Daily (press release) ...proliferation continued. They turned to gene therapy and an adenovirus, which enabled them to express GRK5 in any cell. When they ...

St. Louis U. expands HIV vaccine study Dec 2, 2005
Belleville News-Democrat, AIDS.". The vaccine consists of man-made copies of three HIV genes inserted into an adenovirus, which causes the common cold. The ...

EVMS researchers work to find quick way to develop flu vaccine Nov 22, 2005
WVEC.com (subscription), It could make culturing vaccine in eggs obsolete. "We already have quite a bit of knowledge about how to grow up adenovirus in cell culture and that same ...

Focusing on the Flu Nov 23, 2005
TheHorse.com, ...a litany of equine respiratory illnesses referred to as "the flu" includes infection with equine herpesvirus (rhinopneumonitis), adenovirus, equine viral ...

(Euronext Paris) - Transgene : Clinical Pipeline Update Nov 29, 2005
Euronext, ...significantly impaired by the treatment. TG1042 uses Transgene’s adenovirus vector carrying the interferon gamma gene. TG4001 uses the MVA ...

Transgene: Clinical Pipeline Update Nov 29, 2005
PR Newswire (press release), ...by the treatment. About TG1042: TG1042 uses Transgene's adenovirus vector carrying the interferon gamma gene. About TG4001: TG4001 ...

Mild bronchiolitis can become more serious Nov 23, 2005
Daily News - Galveston County, ...is caused by a viral infection, most commonly respiratory syncytial virus (RSV), but it can also develop with other viruses, such as influenza and adenovirus. ...

Treatment of pancreatic carcinoma by adenoviral mediated gene ... Nov 20, 2005
Xagena.it, The protein gene was incorporated into a virus ( adenovirus ), so that it would be able to penetrate the cells, acting as a vector. ...

Efficient myocyte gene delivery with complete cardiac surgical ... Nov 29, 2005
The Journal of Thoracic and Cardiovascular Surgery Crystalloid cardioplegia at 4°C containing 10 13 particles of adenovirus encoding LacZ and 15 µg of vascular endothelial growth factor was infused retrograde ...

Health Ministry to Source Local Volunteers for Int'l HIV Vaccine ... Nov 18, 2005
Government of Jamaica, Jamaica Information Service, He explained that the vaccine being used is called the adenovirus five, and "acts as a vector, which is like a suitcase, to carry the HIV gene insert, which ...

32 J'cans to participate in HIV vaccine tests Nov 18, 2005
Jamaica Observer, It is made up of a weakened form of cold virus called adenovirus 5 that has been crippled so that it cannot grow or spread to other people and it cannot cause ...

Transgene and the International AIDS Vaccine Initiative (IAVI) ... Nov 17, 2005
PR Newswire (press release), ...in clinical trials. The vaccine candidate uses the Adenovirus-35 vector technology and expresses HIV-1 antigens. Building on Transgene's ...


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