VEGF Trap
information and resources from the National Cancer Institute
NCI Thesaurus | VEGF Trap
A protein comprised of segments of the extracellular domains of human vascular endothelial growth factor receptors 1 (VEGFR1) and 2 (VEGFR2) fused to the constant region (Fc) of human IgG1. VEGF trap binds to vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby preventing VEGF from binding to its cell receptors. Disruption of this cell receptor binding results in the inhibition of angiogenesis and metastasis, and tumor regression.NCI Thesaurus | VEGF Trap
A protein comprised of segments of the extracellular domains of human vascular endothelial growth factor receptors 1 (VEGFR1) and 2 (VEGFR2) fused to the constant region (Fc) of human IgG1. VEGF trap binds to vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby preventing VEGF from binding to its cell receptors. Disruption of this cell receptor binding results in the inhibition of angiogenesis and metastasis, and tumor regression.
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news articles
*vwd/BUSINESS WIRE: Regeneron legt Finanzergebnisse und operative ... Nov 3, 2005
Vereinigte Wirtschaftsdienste, The Vascular Endothelial Growth Factor (VEGF) Trap oncology program, which is being conducted in collaboration with the sanofi-aventis Group, continued to ...
Regeneron still plans layoffs at plant Nov 5, 2005
Albany Times Union, The company is embarking on a number of clinical trials for its vascular endothelial growth factor trap, or VEGF Trap, which it is developing with the Sanofi ...
Regeneron rises after analyst upgrade Oct 24, 2005
BusinessWeek ...jumped to a new 52-week high Monday, after investment firm Morgan Stanley upgraded the biotech company on confidence that its VEGF Trap is positioned to become ...
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