PR1 leukemia peptide vaccine

PR1 leukemia peptide vaccine information and resources from the National Cancer Institute

NCI Thesaurus | PR1 leukemia peptide vaccine

A cancer vaccine consisting of PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3. Vaccination with PR1 leukemia peptide vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Proteinase 3 is often overexpressed in leukemic cells.NCI Thesaurus | PR1 leukemia peptide vaccine

A cancer vaccine consisting of PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3. Vaccination with PR1 leukemia peptide vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Proteinase 3 is often overexpressed in leukemic cells.

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