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Leukoencephalopathy
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Leukoencephalopathy
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Elan's Tysabri gets fast track licence Nov 17, 2005
...they voluntarily suspended TYSABRI from the US market and all ongoing clinical trials based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- Business World,
Regulators OK fast review of multiple sclerosis drug Nov 20, 2005
...immune systems. Such patients could be more susceptible to contracting a disease called progressive multifocal leukoencephalopathy.
- Ventura County Star (subscription),
Biotechs Busier Than Big Pharma Nov 20, 2005
On Friday, Bear Stearns said while further tests of Tysabri showed no new cases of PML, or progressive multifocal leukoencephalopathy, the larger issue of ...
- Forbes
Tysabri Gets Priority Review Nov 17, 2005
The results yielded no new confirmed cases of the brain disease, progressive multifocal leukoencephalopathy, beyond the three that had been previously reported ...
- TheStreet.com
Tysabri may be useful for some patients with Crohn's disease Nov 5, 2005
In an open-label extension study, a patient treated with Natalizumab died from progressive multifocal leukoencephalopathy, associated with the JC virus, a ...
- Xagena.it,
The Pattern of Cognitive Performance in CADASIL: A Monogenic ... Nov 13, 2005
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic variant of small vessel disease resulting ...
- Am J Psychiatry (subscription)
Biogen Says 3rd-Qtr Profit Fell on Increased Costs (Update1) Oct 26, 2005
The drug was withdrawn in February after three patients developed a rare, often-fatal disorder, called progressive multifocal leukoencephalopathy, and two died ...
- Bloomberg
Glaxo, AstraZenenca earnings increase Oct 27, 2005
28 after two patients using combination therapy contracted the rare and usually fatal brain disease called progressive multifocal leukoencephalopathy, or PML ...
- San Jose Mercury News,
Experimental Crohn's, MS Drug Carries Dangers Nov 2, 2005
...the drug, natalizumab (Tysabri), found that while there was some positive response, one patient died from progressive multifocal leukoencephalopathy (PML), a ...
- Forbes
Biogen Idec's Tysabri May Return To Market In 2006 Oct 31, 2005
..."While PML [progressive multifocal leukoencephalopathy] concerns are legitimate, we believe many neurologists will accept the risk/benefit tradeoff and ...
- Forbes
Biogen reports lower earnings on higher revenue Oct 26, 2005
...in February after two patients who used the drug were diagnosed with a rare but deadly brain disease known as PML, or progressive multifocal leukoencephalopathy ...
- MarketWatch
Elan losses shrink on cost cuts, higher drug revenues UPDATE Oct 27, 2005
...the drug after two patients who were using it were diagnosed with a rare but deadly brain disease known as progressive multifocal leukoencephalopathy (PML). ...
- Forbes
Withdrawn drug may help in Crohn's disease Nov 4, 2005
The drug was withdrawn in February after a multiple sclerosis patient died from a brain disorder known as progressive multifocal leukoencephalopathy. ...
- Reuters.uk,
Many Questions for Biogen Oct 25, 2005
Three patients who took the drug during clinical trials developed progressive multifocal leukoencephalopathy, or PML, a debilitating brain disease. ...
- Smartmoney.com
Biogen Idec Reports Third Quarter 2005 Results Oct 26, 2005
...safety evaluation of TYSABRI in patients with Crohn's disease (CD) and RA resulted in no new confirmed cases of progressive multifocal leukoencephalopathy (PML ...
- Business Wire (press release),
Tysabri, Used to Treat MS and Crohn’s Disease, May Have Serious ... Nov 4, 2005
...of the drug natalizumab (Tysabri) found that while there was some positive response, one patient died from progressive multifocal leukoencephalopathy (PML), a ...
- Newsinferno.com,
Charges take toll on Biogen Idec profit Oct 27, 2005
...reported that a safety study of about 1,300 patients had found no new cases of the disorder, called progressive multifocal leukoencephalopathy, raising hopes ...
- Raleigh Triangle Business Journal,
Elan Reports Third Quarter 2005 Financial Results Oct 26, 2005
Disease (CD) and rheumatoid arthritis has been completedand the findings resulted in no new confirmed cases of progressivemultifocal leukoencephalopathy (PML). ...
- Finanzen.net,
Patients' Right to Choose Brief Analysis Oct 25, 2005
...thousand patients were being treated with Tysabri, three confirmed cases of a rare neurological disorder (progressive multifocal leukoencephalopathy, or PML ...
- National Center for Policy Analysis,
JP Morgan Ups Opinion on Biogen Idec to Overweight Oct 31, 2005
He says that while PML (progressive multifocal leukoencephalopathy) concerns are legitimate, he believes many neurologists will accept the risk/benefit ...
- BusinessWeek
Elan Reports Third Quarter 2005 Financial Results Oct 27, 2005
Disease (CD) and rheumatoid arthritis has been completed and the findings resulted in no new confirmed cases of progressive multifocal leukoencephalopathy (PML ...
- PharmaLive.com (press release),
Diffusion Tensor Imaging in Progressive Multifocal ... Sep 29, 2005
Summary: Progressive multifocal leukoencephalopathy is a severe demyelinating disease of the central nervous system caused by a JC papovavirus infection. ...
- Am J Neuroradiology (subscription)
Resurrecting a miracle drug Sep 30, 2005
The neurological disorder linked to Tysabri, progressive multifocal leukoencephalopathy (PML), is caused by a common virus that the immune system usually keeps ...
- Washington Times,
Biogen, Elan file to have Tysabri put back on market Sep 26, 2005
...reports surfaced that two MS patients taking the drug had contracted a rare, but deadly brain disease called progressive multifocal leukoencephalopathy, or PML ...
- MarketWatch
Eye On Stocks For Tuesday, Sept. 27 Sep 26, 2005
...for marketing, we would expect very limited use until more data is provided regarding the risk management of PML [progressive multifocal leukoencephalopathy].". ...
- Forbes
Biogen, Elan seek return of multiple sclerosis drug Sep 26, 2005
The patient died from a brain disorder known as progressive multifocal leukoencephalopathy (PML) and another patient at the time was suspected of having the ...
- Reuters
Makers of MS drug seek to resume sales with revised label Sep 26, 2005
...who have weak immune systems and therefore could be more susceptible to contracting the disease, called progressive multifocal leukoencephalopathy, or PML. ...
- Boston Globe,
Elan, Biogen resubmit Tysabri with US regulators UPDATE Sep 27, 2005
Crohn's. The people contracted a very rare but often fatal brain disease called progressive multifocal leukoencephalopathy, or PML. ...
- Forbes
Mono-Therapy Will Double Elan Sep 28, 2005
The main risk is that three patients have come down with a potentially fatal complication called progressive multifocal leukoencephalopathy, or PML--two have ...
- Forbes
Biogen Idec and Elan Submit Supplemental Biologics License ... Sep 26, 2005
...they voluntarily suspended TYSABRI from the US market and all ongoing clinical trials based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- CCNMatthews (Communiqués de presse),
Biogen, Elan Again Put Fate Of Tysabri Into FDA's Hands Sep 27, 2005
Still, with the agency's risk-averse nature these days and Tysabri's mysterious connection to progressive multifocal leukoencephalopathy (PML), a rare and ...
- BioWorld Online (subscription),
Promising drug's fate unclear Sep 28, 2005
Further investigation found that a patient taking Tysabri for Crohn's disease formed the same infection, called PML (progressive multifocal leukoencephalopathy ...
- OregonLive.com,
Elan & Biogen submit new licence bid Sep 26, 2005
Last February, Elan's shares collapsed after the two companies withdrew Tysbari following three cases of progressive multifocal leukoencephalopathy (PML) in ...
- Business World,
Biogen, Elan Near Tysabri Filing Sep 20, 2005
28 following a report of a suspected rare brain disease -- progressive multifocal leukoencephalopathy, or PML -- linked to the drug. ...
- TheStreet.com
Elan and Biogen hoping to relaunch MS drug Sep 21, 2005
The patient had died from the potentially fatal brain disease progressive multifocal leukoencephalopathy (PML) and another patient at the time was suspected of ...
- Ireland Online,
Elan and Biogen Idec Provide an Update on TYSABRI(R) Sep 20, 2005
...announced the completion of the safety evaluation of TYSABRI in MS, which resulted in no new confirmed cases of progressive multifocal leukoencephalopathy (PML ...
- Genetic Engineering News,
Biogen Idec, Elan continue work on Tysabri Sep 21, 2005
...announced the completion of the safety evaluation of Tysabri in MS, which resulted in no new confirmed cases of progressive multifocal leukoencephalopathy. ...
- Boston Mass High Tech,
Biogen Idec to cut 17 pct. of work force Sep 8, 2005
...just three months after it reached the market amid fears that it could leave patients susceptible to progressive multifocal leukoencephalopathy, or PML, a rare ...
- BusinessWeek
Mullen's Biogen Idec Cuts Jobs To Save Drugs Sep 9, 2005
...for the drug from the US Food and Drug Administration three months earlier, but pulled it after reports of progressive multifocal leukoencephalopathy, a rare ...
- Forbes
Health Highlights: Sept. 1, 2005 Sep 1, 2005
Cammbridge, Mass., company will recommend that the drug, Tysabri, include warnings about three cases of progressive multifocal leukoencephalopathy (PML), that ...
- Atlanta Journal Constitution (subscription),
Business Development Commitment Increased to $200 Million Annually Sep 8, 2005
...voluntarily suspended the marketing and clinical dosing of TYSABRI on February 28, 2005 based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- Genetic Engineering News,
Biogen Idec Cuts 140 Local Jobs Sep 8, 2005
The company made the decision based on reports of progressive multifocal leukoencephalopathy in patients who took Tysabri in clinical trials. ...
- San Diego Business Journal (subscription),
Biogen Idec lays off 650, 140 in San Diego Sep 8, 2005
The drug was withdrawn after it was linked to two cases of a brain disease called progressive multifocal leukoencephalopathy, or PML. ...
- North County Times,
160 to lose jobs at Biogen in RTP Sep 9, 2005
...sales of Tysabri after it was linked to a rare, often-fatal disease of the central nervous system known as PML, or progressive multifocal leukoencephalopathy. ...
- News & Observer,
Despite Benefits, Genzyme Suspends Campath MS Trial Sep 16, 2005
...plc, was pulled from the market in February - just three months after FDA approval - when two patients came down with progressive multifocal leukoencephalopathy ...
- BioWorld Online (subscription),
MS drug's predicted sales are lowered Aug 30, 2005
In a call to investors this month, Biogen Idec officials said they hadn't found any additional cases of PML, or progressive multifocal leukoencephalopathy. ...
- Boston Globe,
Multiple Sclerosis - 2 Year Sentinel Data Evaluating Tysabri® In ...31 Jul 2005
...they voluntarily suspended TYSABRI from the US market and all ongoing clinical trials based on reports of progressive multifocal leukoencephalopathy ( PML ), a ...
- I-Newswire.com
Progressive Multifocal Leukoencephalopathy after Natalizumab ...Jul 27, 2005
...treated with natalizumab, a monoclonal antibody against 4 integrins, was reclassified as JC virus–related progressive multifocal leukoencephalopathy (PML). ...
- New England Journal of Medicine (subscription)
Progressive Multifocal Leukoencephalopathy in a Patient Treated ...Jul 27, 2005
We describe the clinical course of a patient with multiple sclerosis in whom progressive multifocal leukoencephalopathy (PML), an opportunistic viral infection ...
- New England Journal of Medicine (subscription)
HOME | SEARCH | CURRENT ISSUE | PAST ISSUES | COLLECTIONS | HELPJul 27, 2005
A 46-year-old woman with relapsing–remitting multiple sclerosis died from progressive multifocal leukoencephalopathy (PML) after having received 37 doses of ...
- New England Journal of Medicine (subscription)
Elan Reports Second Quarter 2005 Financial ResultsJul 27, 2005
Idec) voluntarily suspended Tysabri from the US market and all ongoing clinical trials based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- Business Wire
Gurus Buy Biotech And Software, Trim Health CareJul 26, 2005
...other cases, too, of patents taking Tysabri coming down with the rare and usually fatal brain disease called progressive multifocal leukoencephalopathy (PML). ...
- Forbes
Biogen Says 2nd-Quarter Profit Rose on Avonex Sales (Update1)Jul 26, 2005
The companies halted sales after the drug was linked to two cases of an often-fatal nervous-system disorder called progressive multifocal leukoencephalopathy. ...
- Bloomberg
Elan reports positive new Tysabri testsJul 19, 2005
...of Tysabri in February this year from the US market and all ongoing clinical trials, based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- Business World
Biogen says Avonex, Tysabri combination met primary endpointJul 18, 2005
Biogen and Elan have reported three confirmed cases of progressive multifocal leukoencephalopathy, or PML, a rare and potentially fatal disease of the central ...
- MarketWatch
Colorado widower sues Elan and BiogenJul 21, 2005
Since then, the companies have attributed a second death to the disease, progressive multifocal leukoencephalopathy, but have declined to comment on additional ...
- Boston Globe
Financials and Elan boost ISEQJul 19, 2005
Idec and Elan suspended Tysabri from the US market and all on-going clinical trials based on reports of progressive multifocal leukoencephalopathy (PML), a ...
- Ireland Online
Biogen, Elan Face Wrongful Death SuitJul 22, 2005
Smith's wife, Anita, 46, died of the rare brain disease progressive multifocal leukoencephalopathy after taking part in a clinical trial of the drug, Tysabri. ...
- Los Angeles Times
Earnings OutlookJul 21, 2005
...of more than 3,000 former Tysabri users to see if they have been stricken with a brain infection known as progressive multifocal leukoencephalopathy, or PML. ...
- MarketWatch
Biogen, Elan hit with lawsuit over TysabriJul 22, 2005
Anita Smith died of progressive multifocal leukoencephalopathy, or PML, a rare and potentially fatal nervous-system disorder the lawsuit alleges has been ...
- Science Daily
Business DigestJul 22, 2005
Smith’s wife, Anita, 46, died of the rare brain disease progressive multifocal leukoencephalopathy after taking part in a clinical trial of the drug, Tysabri ...
- Worcester Telegram (subscription)
Massachusetts Action Commenced Against Biogen and Elan for Tysabri ...Jul 21, 2005
Tysabri and Avonex in the clinical trial, Anita Smith and others developed opportunistic infections including Progressive Multifocal Leukoencephalopathy (“PML ...
- Newsinferno.com
Parker & Waichman, LLP Files Suit Against Biogen Idec, Inc. and ...Jul 21, 2005
Mrs. Smith died of Progressive Multifocal Leukoencephalopathy, or PML, a fatal disorder of the nervous system that has been linked to monotherapy with Tysabri ...
- ArriveNet
Diagnostic Imaging: BrainJul 21, 2005
...you considering a diagnosis of Citrobacter meningitis, remote cerebellar hemorrhage, encephalocraniocutaneous lipomatosis, or van der Knapp leukoencephalopathy ...
- Am J Roentgenology (subscription)
Elan's Tysabri Link to Death May Be From `Overdosing' (Update2)Jul 6, 2005
Tysabri was recalled Feb. 28 after being linked to progressive multifocal leukoencephalopathy, a rare neurological disease in two patients. ...
- Bloomberg
Elan's Tysabri Link to Death May Be From `Overdosing' (Update4)Jul 6, 2005
Tysabri was withdrawn after being linked to progressive multifocal leukoencephalopathy, a rare neurological disease, in two patients, both of whom were taking ...
- Bloomberg
Tysabri deaths may be due to drug interactionJul 6, 2005
Tysabri, jointly developed by Biogen Idec and Dublin-based Elan, was withdrawn after being linked to progressive multifocal leukoencephalopathy, a rare ...
- Boston Herald
With Reports of Death, FDA Warns Multiple Sclerosis (MS) Patients ...Jul 1, 2005
In several cases, the patient or corpse was diagnosed with Progressive Multifocal Leukoencephalopathy (PML), a rare brain infection that directly affects the ...
- Drug Newswire
Warning Issued by FDA on consumption of the drug Tysabri used to ...Jul 3, 2005
A single fatality and one possible case of progressive Multifocal leukoencephalopathy (PML) have been reported in patients receiving Tysabri for MS. ...
- MedIndia
FDA Issues Public Health Advisory on Tysabri, a New Drug for MSJul 3, 2005
...report from Biogen Idec, the manufacturer of Tysabri, of one confirmed fatal case and one possible case of progressive multifocal leukoencephalopathy (PML) in ...
- MedIndia
TYSABRI: THE DRUG THAT REFUSES TO DIEJul 1, 2005
...month, the FDA was informed by Biogen that a fifth person had developed a rare brain disease known as progressive multifocal leukoencephalopathy (PML) after ...
- Newsinferno.com
Biogen, Elan sued for allegedly concealing MS drug risksJul 1, 2005
ELN) pulled the drug after at least one MS patient using it died from a rare nervous system disorder known as progressive multifocal leukoencephalopathy, or PML ...
- Boston Business Journal
Controversial Crohn's Disease Drug Does Well in TrialsJul 1, 2005
...in the United States, but was withdrawn in February after being linked to a rare but deadly brain disease called progressive multifocal leukoencephalopathy (PML ...
- HealthCentral.com
Today's MarketsJul 1, 2005
28 after being linked to two patients who contracted a rare and usually fatal brain disease called progressive multifocal leukoencephalopathy, or PML. ...
- Portsmouth Herald News
This Week in HealthJul 1, 2005
...was withdrawn from the US market earlier this year after it was linked to a rare and deadly brain disease called progressive multifocal leukoencephalopathy. ...
- Intelihealth.com
Crohn’s disease, Tysabri Phase III trial meets primary endpointJul 4, 2005
This decision was based on reports of progressive multifocal leukoencephalopathy ( PML ), a rare and potentially fatal, demyelinating disease of the central ...
- Xagena.it
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Leukoencephalopathy
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