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    Soft-Tissue Sarcomas





    Skeletons in the p53 tumor suppressor closet: genetic evidence ... 14 Mar 2006
    Journal of Cell Biology A substantial percentage of human soft tissue sarcomas and other tumor types harbor wild-type p53 alleles that are inactive because of the amplification and ...

    Cytogenetics Help Predict Outcomes of Soft Tissue Sarcomas Mar 7, 2006
    Cancer Consultants (press release), Researchers from Sweden have reported that cytogenetic examination of soft tissue sarcomas (STS) helps predict the development of metastatic disease in adult ...

    Neoadjuvant Chemotherapy and Radiotherapy Promising for Large Soft ... Mar 3, 2006
    Cancer Consultants (press release), Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, soft tissue sarcomas of the extremities and body wall ...

    PET/CT with Diagnostic CT in the Evaluation of Childhood Sarcoma Feb 14, 2006
    Am J Roentgenology (subscription) Because 18 F-FDG PET is not adequate to exclude pulmonary metastases in bone and soft-tissue sarcomas [4, 5], we suggest that a diagnostic chest CT examination ...

    Neoadjuvant Sarcoma Chemotherapy Results in High Toxicity Levels Mar 1, 2006
    Cancerpage.com, NEW YORK FEB 28, 2006 (Reuters Health) - Combined-modality treatment of high-risk, high-grade soft tissue sarcomas of the extremity and body wall leads to ...

    Sandwich study: Why and how? Feb 11, 2006
    Cape Cod Times, ...diagnosed with leukemia, three children were diagnosed with a central nervous system tumor, two children were diagnosed with soft tissue sarcomas, one child ...

    Carolina Regional Cancer Center announces clinical affiliation ... Feb 16, 2006
    Carolina Newswire (press release), Stephen R. Andrews, DO, has been published for his research on prostate cancer and soft tissue sarcomas. He also has a particular interest in breast cancer. ...

    Douglas High School student battles tumor, disease, state Jan 22, 2006
    The Record-Courier, James has rhabdomyosarcoma, a fast-growing, highly malignant tumor that accounts for over half of the soft tissue sarcomas in children, according to ...

    A War's Unwelcome Vestiges Jan 17, 2006
    TheDay (subscription), ...is on the VA's list, as is chronic lymphocytic leukemia, multiple myeloma, Hodgkin's disease, respiratory cancers, prostate cancer, soft-tissue sarcomas and a ...

    Europe: European stocks rise as dollar strengthens 21 Dec 2005
    International Herald Tribune, It said it would not file for approval for its Yondelis treatment for soft-tissue sarcomas by year's end, missing its own goal, as it and partner Johnson & ...

    New Cancer Treatment System by BSD Medical Acquired to Pioneer ... Dec 13, 2005
    PR Newswire (press release), ...comparing the results of dual treatments with chemotherapy and the BSD-2000 system versus chemotherapy alone for patients with high-risk soft-tissue sarcomas. ...

    Twenty-Seven Percent Of Advanced Sarcoma Patients Experience ... Nov 18, 2005
    DG News The primary objective of the trial is to asses efficacy and safety in four subgroups: bone sarcomas, leiomyosarcoma, liposarcoma and other soft tissue sarcomas ...

    PharmaMar presents pharmacogenomic data on Yondelis® at CTOS Nov 22, 2005
    Biotech Intelligence (press release), ...with Johnson & Johnson Pharmaceutical Research & Development) in Phase III clinical trials; it is also designated Orphan Drug for Soft Tissue Sarcomas and for ...

    Conference considers ultrasound for cancer treatment, noninvasive ... Nov 30, 2005
    uwnews.org, ...four years of clinical use of high-intensity focused ultrasound for liver cancer, malignant bone tumors, breast cancer, soft tissue sarcomas, kidney cancer ...

    Pediatric treatment helps young adults with cancer Nov 24, 2005
    Palm Beach Post, Lauderdale. Cancers common in pediatrics — bone tumors, lymphomas, soft tissue sarcomas — can strike someone into their 20s. ...

    Addition of Avastin® to Chemotherapy May Slow Disease Progression ... Oct 14, 2005
    Cancer Consultants (press release), ...of Avastin® (bevacizumab) to the chemotherapy agent Adriamycin® (doxorubicin) may slow cancer progression in patients with metastatic soft-tissue sarcomas. ...

    Equine Cancer Nov 1, 2005
    TheHorse.com, A two-year followup in the wake of surgery on the horses revealed a tumor control rate of 89% for squamous cell carcinomas and 94% for soft tissue sarcomas. ...

    Sunitinib Prolongs Survival In GIST Patients After Imatinib ... Nov 4, 2005
    DG News ...to the anus. Gastrointestinal stromal tumours (GISTs) belong to a group of cancers called soft tissue sarcomas. They are cancers ...

    Why We Can't Prevent Cancer Nov 4, 2005
    CounterPunch, ...which we have data (1992-2001), liver cancer increased by 39%, thyroid cancer increased by 36%, melanoma increased by 26%, soft tissue sarcomas (including heart ...

    Gene arrangements cause most cases of prostate cancer Oct 29, 2005
    Food Consumer, Although genetic rearrangements were known to occur in leukemia, lymphoma, and soft tissue sarcomas, the gene fusion involved in the prostate cancer is most ...

    Researchers Use New Method to Discover Gene Rearrangements That ... Oct 27, 2005
    National Institutes of Health (press release) Previously, non-random recurrent genetic rearrangements were known to occur only in leukemia, lymphoma, and soft tissue sarcomas. ...

    Prostate cancer tied to genes Oct 28, 2005
    Fort Lauderdale Sun Sentinel, ...one "fused" gene. Similar genes are associated with cancers such as leukemia, lymphoma and soft tissue sarcomas. But the findings ...

    Kids and cancer Oct 23, 2005
    Sun-Sentinel.com, Leukemias, brain and other nervous system tumors, lymphomas, bone cancers, soft-tissue sarcomas, kidney cancers, eye cancers and adrenal gland cancers are the ...




    Malignant (cancerous) tumors that develop in soft tissue are called sarcomas, a term that comes from a Greek word meaning "fleshy growth."

    In this context, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body. Soft tissue includes muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues (tissues around joints).

    There are many different kinds of soft tissue sarcomas. They are grouped together because they share certain microscopic characteristics, produce similar symptoms, and are generally treated in similar ways. (Bone tumors, also known as osteosarcomas, are also called sarcomas, but are in a separate category because they have different clinical and microscopic characteristics and are treated differently.)

    Sarcomas can invade surrounding tissue and can metastasize (spread) to other organs of the body, forming secondary tumors. The cells of secondary tumors are similar to those of the primary (original) cancer. Secondary tumors are referred to as "metastatic soft tissue sarcoma" because they are part of the same cancer and are not a new disease.

    Some tumors of the soft tissue are benign (noncancerous). These tumors do not spread and are rarely life-threatening. However, benign tumors can crowd nearby organs and cause symptoms or interfere with normal body functions.

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